Research Article
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Determination of Biological Activity of Some Macro/Micro Algae

Year 2024, , 1 - 6, 28.06.2024
https://doi.org/10.55385/kastamonujes.1424276

Abstract

Algae are primary producers in the aquatic environment and from an important part of the food chain. Algae have secondary metabolites with high biological activity, which are especially important in the creation of novel pharmaceutical agents. Main purpose of the research was to ascertain antioxidant, anti-alzheimer, anti-diabetic and tyrosinase inhibitory activities of ethanol, hexane and water extracts of some macro/micro algae. Maceration was used as the sample prepatation method. Antioxidant activity of algea for different radical and compound was assessed. Anti-Alzheimer activity of the obtained calluses were determined using Ellman method which is a spectrophotometric method. Anti-diabetic activities were determined using the α-glucosidase inhibition method. It was discovered that the water extract contained more antioxidant phytochemicals, including phenolic (587.54±2.12 mg PEs/g DW) and flavonoids (618.39±2.47 mg QEs/g DW). This study confirmed that the water extract contained high levels of biological acitivty. This extract may be utilized as a possible source of beneficial nutrients or antioxidants.

References

  • Chapman, R.L., Buchheim, M.A. (2001). Green algae and the evolution of land plants: inferences from nuclear-encoded rRNA gene sequences. Biosystems. 28(1-3): 127-137.
  • Barbier, P., Guise, S., Huitorel, P., Amade, P., Pesando, D., Briand, C., Peyrot, V. (1992). Caulerpenyne from Caulerpa taxifolia has an antiproliferative activity on tumor cell line SK-N-SH and modifies the microtubule network. Life science. 70(4): 415-429
  • Belton, G.S., Draisma, S., Van Reine, W.F.P., Huisman, J.M., Gurgel, C.F.D. (2019). A taxonomic reassessment of Caulerpa (Chlorophyta, Caulerpaceae) in southern Australia, based on tufA and rbcL sequence data. Pyhcologica. 58(3): 234-253
  • Ceylan B., Yeşiloğlu, Y. (2022). Investigation of antioxidant activity of Sorbus domestica L. extracts and determination of phenolic contents by LC-MS/MS. Revue Roumaine de Chimie. 67(6-7): 343-351
  • Ertaş, A., Gören, A.C., Boğa, M., Yeşil, Y., Kolak, U. (2014). Essential oil compositions and anticholinesterase activities of two edible plants Tragopogon latifolius var. angustifolius and Lycopsis orientalis. Natural Product Research. 28(17): 1405-1408
  • Thilagam, E., Parimaladevi, B., Kumarappan, C., Mandal, S.C. (2013). α-glucosidase and α-amylase inhibitory activity of Senna surattensis. Journal of Acupuncture and Meridian Studies. 6(1): 24-30
  • Moreno, M.I.N., Isla, M.I., Sampietro, A.R., Vattuone, M.A. (2000). Comparasion of the free radical-scavenging activity of propolis from several regions of Argentina. Journal of Ethnopharmacology. 71(1-2): 109-114
  • Slinkard, K., Singleton V. (1977). Total Phenol Analysis: Automation and Comparasion with Manual Methods. American Journal of Enology and Viticulture. 28: 49-55.
  • Ellman, G.L., Courtney, K.D., Andress, V.J., Feather-Stone, R.M. (1961). A new rapid colorimetric determination of acetylcholinesterase activity. Biochemistry Pharmacology. 7: 88-95
  • Tsujii, E., Muroi, M., Shiragami, N., Takatsuki, A. (1996). Nectrisine is a potent inhibitor of alpha-glucosidases, demonstrating activities similarly at enzyme and cellular levels. Biochemical and Biophysical Research Communications. 220(2): 459-466
  • Keramane, B., Sanchez-Camargo, A.P., Montero, L., Laincer, F., Bedjou, F., Ibanez, E. (2023). Pressurized liquid extraction of bioactive extracts with antioxidant and antibacterial activity from green, red and Brown Algerian algae. Algal Research 76: 103293.12. Ellman GL, Courtney KD, Andress VJ, Feather-Stone RM. A new and rapid colorimetric determination of acetylcholinesterase activity, Biochem. Pharmacology. 7: 88-95
  • Zaid, A. A. A., Hammad, D. M., & Sharaf, E. M. (2015). Antioxidant and anticancer activity of Spirulina platensis water extracts, 11(7): 846-851.
  • Trigui M., Gasmi L., Zouari I., Tounsi S. (2013). Seasonal variation in phenolic composition, antibacterial and antioxidant activities of Ulva rigida (Chlorophyta) and assessment of antiacetylcholinesterase potential. J. Appl. Phycol. 25: 319-328.
Year 2024, , 1 - 6, 28.06.2024
https://doi.org/10.55385/kastamonujes.1424276

Abstract

References

  • Chapman, R.L., Buchheim, M.A. (2001). Green algae and the evolution of land plants: inferences from nuclear-encoded rRNA gene sequences. Biosystems. 28(1-3): 127-137.
  • Barbier, P., Guise, S., Huitorel, P., Amade, P., Pesando, D., Briand, C., Peyrot, V. (1992). Caulerpenyne from Caulerpa taxifolia has an antiproliferative activity on tumor cell line SK-N-SH and modifies the microtubule network. Life science. 70(4): 415-429
  • Belton, G.S., Draisma, S., Van Reine, W.F.P., Huisman, J.M., Gurgel, C.F.D. (2019). A taxonomic reassessment of Caulerpa (Chlorophyta, Caulerpaceae) in southern Australia, based on tufA and rbcL sequence data. Pyhcologica. 58(3): 234-253
  • Ceylan B., Yeşiloğlu, Y. (2022). Investigation of antioxidant activity of Sorbus domestica L. extracts and determination of phenolic contents by LC-MS/MS. Revue Roumaine de Chimie. 67(6-7): 343-351
  • Ertaş, A., Gören, A.C., Boğa, M., Yeşil, Y., Kolak, U. (2014). Essential oil compositions and anticholinesterase activities of two edible plants Tragopogon latifolius var. angustifolius and Lycopsis orientalis. Natural Product Research. 28(17): 1405-1408
  • Thilagam, E., Parimaladevi, B., Kumarappan, C., Mandal, S.C. (2013). α-glucosidase and α-amylase inhibitory activity of Senna surattensis. Journal of Acupuncture and Meridian Studies. 6(1): 24-30
  • Moreno, M.I.N., Isla, M.I., Sampietro, A.R., Vattuone, M.A. (2000). Comparasion of the free radical-scavenging activity of propolis from several regions of Argentina. Journal of Ethnopharmacology. 71(1-2): 109-114
  • Slinkard, K., Singleton V. (1977). Total Phenol Analysis: Automation and Comparasion with Manual Methods. American Journal of Enology and Viticulture. 28: 49-55.
  • Ellman, G.L., Courtney, K.D., Andress, V.J., Feather-Stone, R.M. (1961). A new rapid colorimetric determination of acetylcholinesterase activity. Biochemistry Pharmacology. 7: 88-95
  • Tsujii, E., Muroi, M., Shiragami, N., Takatsuki, A. (1996). Nectrisine is a potent inhibitor of alpha-glucosidases, demonstrating activities similarly at enzyme and cellular levels. Biochemical and Biophysical Research Communications. 220(2): 459-466
  • Keramane, B., Sanchez-Camargo, A.P., Montero, L., Laincer, F., Bedjou, F., Ibanez, E. (2023). Pressurized liquid extraction of bioactive extracts with antioxidant and antibacterial activity from green, red and Brown Algerian algae. Algal Research 76: 103293.12. Ellman GL, Courtney KD, Andress VJ, Feather-Stone RM. A new and rapid colorimetric determination of acetylcholinesterase activity, Biochem. Pharmacology. 7: 88-95
  • Zaid, A. A. A., Hammad, D. M., & Sharaf, E. M. (2015). Antioxidant and anticancer activity of Spirulina platensis water extracts, 11(7): 846-851.
  • Trigui M., Gasmi L., Zouari I., Tounsi S. (2013). Seasonal variation in phenolic composition, antibacterial and antioxidant activities of Ulva rigida (Chlorophyta) and assessment of antiacetylcholinesterase potential. J. Appl. Phycol. 25: 319-328.
There are 13 citations in total.

Details

Primary Language English
Subjects Instrumental Methods
Journal Section Research Article
Authors

Burhan Ceylan 0000-0003-3666-8187

Göksal Sezen 0000-0001-9054-851X

Publication Date June 28, 2024
Submission Date January 23, 2024
Acceptance Date June 8, 2024
Published in Issue Year 2024

Cite

APA Ceylan, B., & Sezen, G. (2024). Determination of Biological Activity of Some Macro/Micro Algae. Kastamonu University Journal of Engineering and Sciences, 10(1), 1-6. https://doi.org/10.55385/kastamonujes.1424276
AMA Ceylan B, Sezen G. Determination of Biological Activity of Some Macro/Micro Algae. KUJES. June 2024;10(1):1-6. doi:10.55385/kastamonujes.1424276
Chicago Ceylan, Burhan, and Göksal Sezen. “Determination of Biological Activity of Some Macro/Micro Algae”. Kastamonu University Journal of Engineering and Sciences 10, no. 1 (June 2024): 1-6. https://doi.org/10.55385/kastamonujes.1424276.
EndNote Ceylan B, Sezen G (June 1, 2024) Determination of Biological Activity of Some Macro/Micro Algae. Kastamonu University Journal of Engineering and Sciences 10 1 1–6.
IEEE B. Ceylan and G. Sezen, “Determination of Biological Activity of Some Macro/Micro Algae”, KUJES, vol. 10, no. 1, pp. 1–6, 2024, doi: 10.55385/kastamonujes.1424276.
ISNAD Ceylan, Burhan - Sezen, Göksal. “Determination of Biological Activity of Some Macro/Micro Algae”. Kastamonu University Journal of Engineering and Sciences 10/1 (June 2024), 1-6. https://doi.org/10.55385/kastamonujes.1424276.
JAMA Ceylan B, Sezen G. Determination of Biological Activity of Some Macro/Micro Algae. KUJES. 2024;10:1–6.
MLA Ceylan, Burhan and Göksal Sezen. “Determination of Biological Activity of Some Macro/Micro Algae”. Kastamonu University Journal of Engineering and Sciences, vol. 10, no. 1, 2024, pp. 1-6, doi:10.55385/kastamonujes.1424276.
Vancouver Ceylan B, Sezen G. Determination of Biological Activity of Some Macro/Micro Algae. KUJES. 2024;10(1):1-6.