INVESTIGATION OF PLEOMORPHIC ADENOMAS IN SALIVARY GLAND, CORRELATION BETWEEN TISSUE BIOPSY AND FINE NEEDLE ASPIRATION CYTOLOGY

Year 2020, Volume: 21 Issue: 1, 30 - 34, 16.01.2020

Figen Aslan Ülkü Küçük

https://doi.org/10.18229/kocatepetip.482856

Abstract

OBJECTIVE: Pleomorphic adenoma is the most com-mon tumor of the salivary gland but there are very few studies that reflect the characteristics of the tumor. Our aim is to investigate the histopathological and clinico-pathological features of this tumor and to investigate the characteristics of fine needle aspiration cytology and its compatibility with tissue biopsy.

MATERIAL AND METHODS: 85 cases with pleomorphic adenoma were evaluated. The demographic characteris-tics, clinicopathological features and operative data of the patients were recorded retrospectively. The results of fine needle aspiration biopsy (FNAB) before the ope-ration were documented and the compliance of FNAB results with tissue biopsy was evaluated.

RESULTS: The male to female ratio in our patients was 1/1.96 and the mean age was 44.45 (11-87). Most of our cases were in the 40-59 age range (41.57%). The tumor was seen in the parotid gland in the majority (59%) and in the minor salivary glands in the 2nd order (18%). The mean tumor diameter was 3.23 cm (1-9 cm) and the tu-mor diameter was most frequent (57.30%) in the range of 2-4 cm. The classical type was the most common (94.4%) histological type. Recurrence was seen in only 1 (1.40%) of benign cases. Malignant transformation in the tumor was present in 5 (5.61%) cases. The diagnosis of pleo-morphic adenoma was as high as 80.32% with preope-rative FNAB.

CONCLUSIONS: Pleomorphic adenoma is most often seen in the parotid gland and is usually located in the su-perficial lobe. It is more frequent in the 4th to 5th decade and in the female gender. Tumor diameter is more in the range of 2-4 cm. The tumor has a low rate of recurrence and malignant transformation. Preoperative FNAB has a high diagnostic accuracy and FNAB is very important for the correct treatment approach.

Keywords

Pleomorpic adenoma, salivary gland, tu-mor, FNAB

TÜKÜRÜK BEZİNDE PLEOMORFİK ADENOMLARIN İNCELENMESİ, İNCE İĞNE ASPİRASYON SİTOLOJİSİNİN DOKU BİYOPSİSİ İLE KORELASYONU

Abstract

AMAÇ: Pleomorfik adenom, tükürük
bezinin en sık görülen tümörüdür fakat 
tümörün özelliklerini yansıtan çok az sayıda çalışma bulunmaktadır.
Amacımız bu tümörün histopatolojik ve klinikopatolojik özelliklerini incelemek
ayrıca ince iğne aspirasyon sitolojisinin özelliklerini ve doku biopsisi ile
uyumunu araştırmak.

GEREÇ VE
YÖNTEM:
Pleomorfik adenom tanısı alan 85 olgu incelendi. Olguların demografik
özellikleri, klinikopatolojik özellikleri ve operatif verileri retrospektif
olarak kaydedildi. Operasyondan önceki 
İİAB sonuçları dökümante edildi ve İİAB sonuçlarının doku biopsisi ile
uyumu değerlendirildi.

BULGULAR: Olgularımızda erkek-kadın oranı: 1/1.96 ve yaş
ortalaması 44.45 idi (11-87). Olgularımızın çoğu 40-59 yaş aralığındaydı
(%41.57). Tümör en fazla (%59) parotis bezinde, 2. sıklıkta (%18) minör tükürük
bezlerinde görüldü. Ortalama tümör çapı 3.23 cm idi (1-9 cm) ve tümör çapı en
sık (%57.30) 2-4 cm aralığındaydı. Klasik tip en fazla görülen (%94.4) histolojik
tipti. Rekürrens benign olguların sadece 1’inde (%1.40) görüldü. Tümörde
malign transformasyon olgularımızın 5’inde (% 5.61) vardı. Operasyondan önce
yapılan İİAB ile %80.32 gibi yüksek oranda PA tanısı verilmişti.

SONUÇ: Pleomorfik adenom en fazla
parotis bezinde görülür ve burada da çoğunlukla yüzeyel  lobda yerleşir. 4.-5. dekadlarda ve kadın cinsiyette
daha sıktır. Tümör çapı 2-4 cm aralığında daha fazla görülür. Tümörün düşük
oranda nüks ve  malign transformasyon
olasılığı vardır. Preoperatif İİAB’nin tanısal doğruluğu oldukça yüksektir ve
İİAB yapılması doğru tedavi yaklaşımı açısından çok önemlidir.

ANAHTAR
KELİMELER: pleomorfik
adenom, tükürük bezi, tümör, İİAB

 

ABSTRACT

OBJECTIVE: Pleomorphic adenoma is the most
common tumor of the salivary gland but there are very few studies that reflect
the characteristics of the tumor. Our aim is to investigate the histopathological
and clinicopathological features of this tumor and to investigate the
characteristics of fine needle aspiration cytology and its compatibility with
tissue biopsy.

MATERIAL AND
METHODS:
85 cases with pleomorphic adenoma were evaluated. The demographic
characteristics, clinicopathological features and operative data of the
patients were recorded retrospectively. The results of FNAB before the
operation were documented and the compliance of FNAB results with tissue biopsy
was evaluated.

RESULTS: The male to female ratio in our patients was 1/1.96 and the mean age was
44.45 (11-87). Most of our cases were in the 40-59 age range (41.57%). The tumor was seen in the parotid gland in the majority (59%) and in the
minor salivary glands in the 2nd order (18%). The mean tumor diameter was 3.23
cm (1-9 cm) and the tumor diameter was most frequent (57.30%) in the range of
2-4 cm.
The classical type was the most common (94.4%) histological type.
Recurrence was seen in only 1 (1.40%) of benign cases. Malignant transformation
in the tumor was present in 5 (5.61%) cases. The diagnosis of PA was as high as 80.32%
with preoperative FNAB.

CONCLUSIONS: Pleomorphic adenoma is most
often seen in the parotid gland and is usually located in the superficial lobe.
It is more frequent in the 4th to 5th decade and in the female gender. Tumor
diameter is more in the range of 2-4 cm. The tumor has a low rate of recurrence
and malignant transformation. Preoperative FNAB has a high diagnostic accuracy
and FNAB is very important for the correct treatment approach.

KEYWORDS: Pleomorphic adenoma, salivary gland, tumor, FNAB

 

Keywords

pleomorfik adenom, tükürük bezi, tümör

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