Fibromiyalji Hastalarında D Vitamini Eksikliğinin Fiziksel Semptomlara Etkisinin İncelenmesi

Yıl 2021, Cilt: 16 Sayı: 3, 421 - 431, 01.11.2021

İhsan Karabulut , Deniz Kocamaz , Begümhan Turhan

https://doi.org/10.17517/ksutfd.818963

Öz

Amaç: Amacımız fibromiyalji hastalarında D vitamini eksikliğinin fiziksel semptomlara etkisini inceleyen araştırmaları taramaktır.
Gereç ve Yöntemler: Çalışmada Pubmed ve Google Scholar veri tabanlarında anahtar kelimeler ile uyumlu tüm Türkçe ve İngilizce çalışmalar tarandı. Anahtar kelime olarak İngilizce dilinde ‘fibromyalgia’ ve ‘Vitamin D’ kelimeleri Türkçe dilinde ‘fibromiyalji’ ve ‘D vitamini’ anahtar kelimeleri kullanıldı.
Bulgular: 2 anahtar kelimenin başlıkta yer aldığı ve fiziksel bulguları inceleyen çalışma sayısı 20’dir. Araştırmaya dahil edilen 2230 bireyin yer aldığı çalışmaların dokuzu ulusal, 11’i uluslararası çalışmalardı. 20 çalışmadan sekizi hasta grubundan, 12’si hasta ve kontrol grubundan oluşmaktadır. Altı çalışmada D vitamini replasman tedavisi bulunmaktaydı. Çalışmalarda ağrı, uyku durumu, yorgunluk, fibromiyalji etkinliği, yaşam kalitesi, anksiyete, depresyon, cinsellik, denge parametreleri incelenmiştir. Ağrı, yorgunluk, uyku durumu en fazla incelenen fiziksel bulgulardır.
Sonuç: Fibromiyalji hastalarında D vitamini eksikliğinin ağrıyı ve fibromiyalji belirtilerini arttırdığı, yaşam kalitesini, uyku süresini ve dengeyi azalttığı, yorgunluk düzeyi açısından anlamlı bir farklılık oluşturmadığı gözlenmektedir.

Anahtar Kelimeler

Fibromiyalji, D vitamini, Fiziksel bulgular

Investigation of the Effect of Vitamin D Deficiency on Physical Symptoms in Fibromyalgia Patients: Systematic Review

Öz

Aim: Our aim is to investigate the studies investigating the effect of vitamin D deficiency on physical symptoms in fibromyalgia patients.
Materials and Methods: All studies that were according with keywords in Turkish and English languages which were published in Pubmed and Google Scholar databases were scanned. The keywords 'fibromyalgia' and 'Vitamin D' were used as keywords in the English language, the keywords 'fibromiyalji' and 'D vitamini' were used in the Turkish language.
Results: The number of studies with 2 keywords in the title and examining the physical findings is 20. Of the 2230 individuals included in the study, 9 were national and 11 were international studies. Of the 20 studies, 8 consisted of the patient group and 12 consisted of the patient and control groups. Six studies had vitamin D replacement therapy. In the studies, pain, sleepiness, fatigue, fibromyalgia efficacy, quality of life, anxiety, depression, sexuality, balance parameters were examined. Pain, fatigue, sleep state are the most frequently examined physical findings.
Conclusion: It is observed that vitamin D deficiency in fibromyalgia patients increases pain and fibromyalgia symptoms, decreases quality of life, sleep time and balance, and does not make a significant difference in terms of fatigue level.

Anahtar Kelimeler

fibromyalgia, Vitamin D, Physical findings

Kaynakça

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