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Kikuchi-Fujimoto Disease or Lymphoma?

Year 2022, Volume: 17 Issue: 2, 240 - 243, 15.07.2022
https://doi.org/10.17517/ksutfd.900042

Abstract

Kikuchi-Fujimoto disease is a rare, idiopathic and usually self-limiting disease caused by lymphadenitis. The main symptoms are lymphadenopathy and fever, and less frequent symptoms are night sweats, arthralgia, weight loss and rashes. A case of a 16 years old boy is presented. His complaints were cervical mass presenting for about three weeks, night sweats, weight loss and fatigue. Our aim is that in the differential diagnosis of fever and lymphadenopathy of unknown origin, diseases such as lymphoma and tuberculosis, as well as rare and mostly very benign Kikuchi-Fujimoto disease should be remembered.

References

  • Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytosis. Nippon Ketsueki Gakkai Zasshi. 1972;35:378–380.
  • Fujimoto Y, Kozima Y, Hamaguchi K. Cervical necrotizing lymphadenitis: a new clinicopathological agent. Naika. 1972;20:920– 927.
  • Dumas G, Prendki V, Haroche J, Amoura Z, Cacoub P, Galicier L et al. Kikuchi-Fujimoto disease: retrospective study of 91 cases and review of the literature. Medicine (Baltimore). 2014;93(24):372–382.
  • Perry AM, Choi SM. Kikuchi-Fujimoto Disease: A Review. Arch Pathol Lab Med. 2018;142(11):1341-1346.
  • Singh JM, Shermetaro CB. Kikuchi-Fujimoto disease in Michigan: a rare case report and review of the literatüre. Clin Med Insights: Ear, Nose and Throat. 2019;12:1-5.
  • Jamal AB. Kikuchi-Fujimoto disease. Clin Med Insights Arthritis Musculoskelet Disord. 2012;5:63–6.
  • Lin HC, Su CY, Huang CC, Hwang CF, Chien CY. Kikuchi’s disease: a review and analysis of 61 cases. Otolaryngology. 2003;128(5):650–3.
  • Lelii M, Senatore L, Amodeo I, Pinzani R, Torretta S, Fiori S et al. Kikuchi-Fujimoto disease in children: two case reports and a review of the literature. Ital J Pediatr. 2018;44:83.
  • Kucukardali Y, Solmazgul E, Kunter E, Oncul O, Yildirim S, Kaplan M. Kikuchi-Fujimoto Disease: analysis of 244 cases. Clin Rheumatol. 2007;26(1):50-54.
  • Atwater AR, Longley BJ, Aughenbaugh WD. Kikuchi’s disease: case report and systematic review of cutaneous and histopathologic presentations. J Am Acad Dermatol. 2008;59:130–136.
  • Al Mosawi Z, Ebrahim B, Baik S, Madan W, Aljufairi E. Kikuchi- Fujimoto Disease: Eleven pediatric cases and literature review. Arch Rheumatol. 2020;35(2):303-307.
  • Deaver D, Naghashpour M, Sokol L. Kikuchi-Fujimoto disease in the United States: three case reports and review of the literatüre. Mediterr J Hematol Infect Dis. 2014;6(1):e2014001.
  • Lee BC, Patel R. Kikuchi-Fujimoto Disease: A 15-year analysis at a children’ s hospital in the United States. Clin Pediatr. 2013;52:92-95.
  • Hutchinson CB, Wang E. Kikuchi-fujimoto disease. Arch Pathol Lab Med. 2010;134(2):289–293.
  • Lin YW, Horiuchi H, Ueda I, Nambu M. Recurrent hemophagocytic lymphohistiocytosis accompanied by Kikuchi’s disease. Leuk Lymphoma. 2007;48:2447–2451.
  • Quadir A, Peacock K, Hsu P, Singh-Grewal D, Alexander S. A familial case of Kikuchi-Fujimoto disease in dizygotic twins. Pediatr Rheumatol Online J. 2020;18(1):62.

Kikuchi-Fujimoto Hastalığı mı, Lenfoma mı?

Year 2022, Volume: 17 Issue: 2, 240 - 243, 15.07.2022
https://doi.org/10.17517/ksutfd.900042

Abstract

Özet
Kikuchi-Fujimoto hastalığı kendi kendini sınırlayan bir hastalık olup lenfadenitin oldukça nadir görülen sebeplerinden biridir. Başlıca semptomları lenfadenopati ve ateştir. Daha nadir olarak gece terlemesi, artralji, kilo kaybı ve cilt bulguları görülebilir. Bu yazıda üç haftadır mevcut olan servikal bölgede kitle,
gece terlemesi, kilo kaybı ve yorgunluk şikayetleri olan 16 yaşında erkek hasta sunulmuştur. Yazının amacı, nedeni belirsiz ateş ve lenfadenopatinin ayırıcı tanısında lenfoma ve tüberküloz gibi hastalıkların yanı sıra nadir görülen ve genellikle iyi seyirli olan Kikuchi-Fujimoto hastalığının da akılda tutulmasını
vurgulamaktır.

References

  • Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytosis. Nippon Ketsueki Gakkai Zasshi. 1972;35:378–380.
  • Fujimoto Y, Kozima Y, Hamaguchi K. Cervical necrotizing lymphadenitis: a new clinicopathological agent. Naika. 1972;20:920– 927.
  • Dumas G, Prendki V, Haroche J, Amoura Z, Cacoub P, Galicier L et al. Kikuchi-Fujimoto disease: retrospective study of 91 cases and review of the literature. Medicine (Baltimore). 2014;93(24):372–382.
  • Perry AM, Choi SM. Kikuchi-Fujimoto Disease: A Review. Arch Pathol Lab Med. 2018;142(11):1341-1346.
  • Singh JM, Shermetaro CB. Kikuchi-Fujimoto disease in Michigan: a rare case report and review of the literatüre. Clin Med Insights: Ear, Nose and Throat. 2019;12:1-5.
  • Jamal AB. Kikuchi-Fujimoto disease. Clin Med Insights Arthritis Musculoskelet Disord. 2012;5:63–6.
  • Lin HC, Su CY, Huang CC, Hwang CF, Chien CY. Kikuchi’s disease: a review and analysis of 61 cases. Otolaryngology. 2003;128(5):650–3.
  • Lelii M, Senatore L, Amodeo I, Pinzani R, Torretta S, Fiori S et al. Kikuchi-Fujimoto disease in children: two case reports and a review of the literature. Ital J Pediatr. 2018;44:83.
  • Kucukardali Y, Solmazgul E, Kunter E, Oncul O, Yildirim S, Kaplan M. Kikuchi-Fujimoto Disease: analysis of 244 cases. Clin Rheumatol. 2007;26(1):50-54.
  • Atwater AR, Longley BJ, Aughenbaugh WD. Kikuchi’s disease: case report and systematic review of cutaneous and histopathologic presentations. J Am Acad Dermatol. 2008;59:130–136.
  • Al Mosawi Z, Ebrahim B, Baik S, Madan W, Aljufairi E. Kikuchi- Fujimoto Disease: Eleven pediatric cases and literature review. Arch Rheumatol. 2020;35(2):303-307.
  • Deaver D, Naghashpour M, Sokol L. Kikuchi-Fujimoto disease in the United States: three case reports and review of the literatüre. Mediterr J Hematol Infect Dis. 2014;6(1):e2014001.
  • Lee BC, Patel R. Kikuchi-Fujimoto Disease: A 15-year analysis at a children’ s hospital in the United States. Clin Pediatr. 2013;52:92-95.
  • Hutchinson CB, Wang E. Kikuchi-fujimoto disease. Arch Pathol Lab Med. 2010;134(2):289–293.
  • Lin YW, Horiuchi H, Ueda I, Nambu M. Recurrent hemophagocytic lymphohistiocytosis accompanied by Kikuchi’s disease. Leuk Lymphoma. 2007;48:2447–2451.
  • Quadir A, Peacock K, Hsu P, Singh-Grewal D, Alexander S. A familial case of Kikuchi-Fujimoto disease in dizygotic twins. Pediatr Rheumatol Online J. 2020;18(1):62.
There are 16 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Olgu Sunumları
Authors

Sema Yıldırım 0000-0001-7311-519X

Ayşe Aşık This is me 0000-0003-0973-8098

Bengü Çobanoğlu Şimşek 0000-0003-2639-2017

Ayşe Bozkurt This is me 0000-0002-6671-0596

Early Pub Date July 11, 2022
Publication Date July 15, 2022
Submission Date March 22, 2021
Acceptance Date July 5, 2021
Published in Issue Year 2022 Volume: 17 Issue: 2

Cite

AMA Yıldırım S, Aşık A, Çobanoğlu Şimşek B, Bozkurt A. Kikuchi-Fujimoto Disease or Lymphoma?. KSU Medical Journal. July 2022;17(2):240-243. doi:10.17517/ksutfd.900042