Yeni Tanı Almış Kovid-19 Hastalarında Tedavi Öncesi Nazal Mukosiliyer Temizliğin Değerlendirilmesi

Abstract

Amaç: Çalışmamızın amacı yeni tanı almış ve henüz tedavi başlanmamış COVİD 19 hastalarında nasal mucocilier klirensi (NMC) değerlendirerek covid 19 un NMC yi nasıl etkilediğini araştırmaktır. Gereç ve Yöntem: Çalışmamıza Düzce Atatürk Devlet Hastanesine 2020 yılı eylülkasım ayları arasında başvuran toplam 120 kişi alındı. Bunların 60 tanesi covid 19 tanısı almış hastalardı. 60 tanesi de kontrol grubuydu. Yaş aralığı 18-66 ydı. Çalışmamıza covid 19 tanısı almış ve tedavi başlanmamış 60 kişi alındı. Tat bozukluğu olanlar çalışmaya alınmadı. Kontrol grubu olarak ta 60 sağlıklı gönüllü alındı. NMC sakkarin test ile değerlendirildi. Sonuçlar Statistical Package for Social Sciences (SPSS) te karşılaştırıldı. Bulgular: Çalışmamızda 60 Covid 19 tanısı alan ve tedavi başlanmamış çalışma grubu ve 60 sağlıklı kontrol grubu değerlendirildi. Yaş ortalaması çalışma grubunda 40,72±12,96 kontrol grubunda 39,16 idi Ortalama NMC çalışma grubunda 15,95±3,37idi, kontrol grubunda ise 8,38±1,03 idi. İstatiksel olarak değerlendirildiğinde çalışma grubunda daha yüksek bulundu (p<0,001). Sonuç: Sonuç olarak NMC Covid 19+ hastalarında uzamaktadır

Keywords

• Kovid 19
• Nazal Mukosiliyer Klirens
• Koku Bozuklukları

Evaluation of Nasal Mucociliary Clearance in Recently Diagnosed Covid-19 Patients Before Treatment

Abstract

Objective: Our study aims to evaluate the nasal mucociliary clearance (NMC) in Covid-19 patients who have been recently diagnosed and not been treated yet and investigate how Covid-19 affects NMC. Methods: A total of 120 participants, who applied to Düzce Atatürk State Hospital between September and November 2020, were included in our study. 60 of them were the participants, diagnosed with Covid-19. And 60 of them were the control group. The age range was 18 to 66. 60 participants, diagnosed with Covid-19 and not yet treated, were included in our study. Those with taste disorders were excluded from the study. The control group consisted of 60 healthy volunteers. NMC was evaluated using a saccharin test. The results were compared in the Statistical Package for Social Sciences (SPSS). Results: The study group, which consisted of 60 Covid-19 participants of whom treatment was not yet started, and the 60-participant healthy control group were evaluated in our study. The average age of the study group was 40,72±12,96 and 39,16 in the control group. The average NMC was 15,95±3,37 in the study group, and 8,38±1,03 in the control group. When evaluated statistically, it was found higher in the study group (p<0,001). Conclusions: NMC acts as a barrier for inhaled foreign bodies. It is a non-specific protection system against airborne pathogens. Consequently, NMC extends in Covid- 19 patients.

Keywords

• Covid 19
• Smell Disorders
• Nasal Mucociliary Clearence

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