Cilt Kanserlerinin 20 Yıllık Retrospektif Analizi: Birinci 10 Yıl İle İkinci 10 Yılın Karşılaştırılması

Year 2020, Volume: 12 Issue: 3, 463 - 472, 20.10.2020

Handan Derebaşınlıoğlu , Sanem Nemmezi Karaca

https://doi.org/10.18521/ktd.708364

Abstract

Amaç: Çevresel faktörlere bağlı olarak cilt kanserlerinin insidansı gün geçtikçe artmaktadır. Gelişen tanısal ve patolojik metotlar kanserlerin daha doğru tiplendirilmesine yardımcı olmaktadır.

Yöntem: Çalışmamızda cilt kanserleri ve in situ karsinom nedeniyle 1 Ocak 2000-31 Aralık 2019 tarihleri arasında kliniğimizde tedavi amacıyla başvuran ve tedavisi planlanan hastalar dahil edildi. Hastalar ilk on yıl ikinci on yıl olarak iki gruba ayrıldı. Gruplar; kanser tipi, yaş, cinsiyet ve lokalizasyon açısından karşılaştırıldı.

Bulgular: 619 vakaya ait 652 cilt kanseri ve insitu karsinom tespit edildi. Gruplar karşılaştırıldığında ikinci on yılda malign melanoma, Bowen hastalığında ve nadir gözlenen Non Melanositik Cilt Kanseri (NMCK)’nin alt tiplerinde anlamlı bir artış olduğu gözlendi (p<0,001). NMCK ve Melanositik Cilt Kanseri (MCK) karşılaştırıldığında MCK insidansının son 10 yılda %5.2 den % 10 a yükselmesi istatistiksel açıdan anlamlı idi (p<0,05).

Sonuç: Nadir gözlenen NMCK’ler çeşitli tedavi protokolleri olan pek çok karsinom tiplerini içermektedir. Ayrıca bu grubun pek çok üyesinin Bazal Hücreli Kanser ve Skuamöz Hücreli Kanserden daha agresif seyrettikleri bilinmektedir. Özellikle lenf nodlarına karşı yaklaşım hakkında ortak bir konsensüs bulunmamaktadır. Rekürens ve metastazların erken tespit edilebilmesi için yakın takip gereklidir.

Keywords

Deri kanseri, Melanositik deri kanseri, Merkel hücreli karsinom, Malign ekrin poroma, Malign noduler hidradenom

Supporting Institution

yok

A 20-Year Retrospective Analysis of Skin Cancers: Comparison of the First and Second Decades

Abstract

Objective: The incidence of skin cancer increases day by day depending on environmental factors. Developing diagnostic and pathological methods provide correct typing of skin cancers.

Method: This retrospective analysis included patients who presented to and were scheduled for treatment at Sivas Cumhuriyet University Plastic Reconstructive and Aesthetic Surgery Clinic between January 1, 2000 and December 31, 2019 due to skin cancer and carcinoma in situ. The results were divided two groups as first ten years and second ten years. The groups were compared among themself in terms of cancer type, age, gender and localization

Results: 619 cases' 652 skin cancer and in situ carcinoma results were detected. When the groups were compared in terms of tumor types detected, there was a significant increase in MM, Bowen's disease, and rare NMSC subtypes other than SCC and BCC in the second decade (p<0.001). Comparison of NMSC and MSC rates between the groups showed that the incidence of MSC had increased significantly from 5.2% to 10% in the past 10 years (p<0,05)

Conclusion: Rare Non-melanocytic skin cancer group includes many types of carcinoma, there are various treatment protocols. Furthermore, many members of this group are known to be more aggressive than Basal cell carcinoma and squamous cell carcinoma. There are no consesnsus especially for approaches targeting lymph nodes. Closely following is necessary for early detection of recurrences and metastases.

Keywords

Skin cancer, Non-melanocytic skin cancer, melanocytic skin cancer

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