BibTex RIS Cite

Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi

Year 2015, , 46 - 50, 05.01.2016
https://doi.org/10.24938/kutfd.124930

Abstract

Tiroid hastalıkları Dünya popülasyonu üzerinde her geçen gün daha sık görülür hale gelmektedir. Her ne kadar klinisyenler tiroid bezinin oto-immün ve malign problemlerine odaklansa da anatomik ve embriyolojik patolojiler de göz önünde bulundurulmalıdır. Tiroid bezinin gelişimsel anomalileri nadirdir ve hemiagenezi yaklaşık %0,05-0,2 sıklıkta ve genellikle sol lobun yokluğuyla görülür. 38 yaşında bayan hasta kliniğimize uzun süredir devam eden, boyunda şişlik ve ağrı şikâyeti ile başvurdu. Muayene ile tiroidin sağ lobunda belirgin büyüme mevcuttu. Tiroid fonksiyon testleri normal olan hastanın radyolojik ve sintigrafik incelemelerinde tiroid bezi sağ lobunda en büyüğü 20 mm olan multiple hipoekoik nodüller tespit edilirken, sol lobu ise tespit edilemedi. İnce iğne aspirasyon biyopsi ile yapılan sitolojik değerlendirme sonucunun kuşkulu olarak bildirilmesi üzerine, hastaya sağ total lobektomi uygulandı. Ameliyat esnasında yapılan değerlendirmede sol lob izlenmedi. Postoperatif histopatolojik değerlendirmesinde sağ lobun tamamında multiple kolloidal benign nodüller saptandı.

Cerrahi girişim planlanan vakalarda diğer lobun durumunu bilmek, yapılacak olan tek taraflı lobektomiler sonrası tiroid bezinin total kaybına neden olmak ve hemiagenezi olan tarafa yapılabilecek gereksiz cerrahi girişimleri ve bu nedenle doğabilecek komplikasyonları önleme açısından önemlidir.

References

  • Brunicandi FC, Billiar TR, Dunn DL, Hunter JG, Matthews JB, Pollock RE. Schwartz’s Principles of Surgery. 10th ed. McGraw-Hill Inc, 2014: 1688-90.
  • Bhartiya S, Verma A, Basu S, Shukla V. Congenital thyroid hemiagenesis with multinodular goiter. Acta Radiologica Short Reports. 2014; 3: 2047981614530286.
  • Ranade A, Rai R, Pai M, Nayak S, Krisnamurthy A, Narayana S. Anatomical variations of the thyroid gland: possible surgical implications. Singapore Medical Journal. 2008; 49(10): 831-4.
  • Velayutham K, Mahadevan S, Velayutham L, Jayapaul M, Appakalai B, Kannan A. A case of hemiagenesis of thyroid with double ectopic thyroid tissue. Indian Journal of Endocrinology and Metabolism. 2013; 17(4): 756-8.
  • Kroeker TR, Stancoven KM, Preskitt JT. Parathyroid adenoma on the ipsilateral side of thyroid hemiagenesis. Proceedings (Baylor University Medical Center). 2011; 24(2): 92-3.
  • Wu Y-HE, Wein RO, Carter B. Thyroid hemiagenesis: a case series and review of the literature. American Journal of Otolaryngology. 2012; 33: 299-302.
  • Chang J, Gerscovich EO, Dublin AB, McGahan JP. Thyroid hemiagenesis: a rare finding. Journal of Ultrasound in Medicine. 2011; 30: 1309-10.
  • Szczepanek-Parulska E, Szaflarski W, Piątek K, Budny B, Jaszczyńska-Nowinka K, Biczysko M. Alternative 3’acceptor site in the exon 2 of human PAX8 gene resulting in the expression of unknown mRNA variant found in thyroid hemiagenesis and some types of cancers. Acta Biochimica Polonica. 2013; 60: 573-8.
  • Oruci M, Ito Y, Buta M, Radisavljevic Z, Pupic G, Djurisic I, et al. Right thyroid hemiagenesis with adenoma and hyperplasia of parathyroid glands-case report. BMC Endocrine Disorders. 2012; 12: 29 doi: 10.1186/1472-6823-12-29.
  • Ruchala M, Szczepanek E, Szaflarski W, Moczko J, Czarnywojtek A, Pietz L. Increased risk of thyroid pathology in patients with thyroid hemiagenesis: results of a large cohort case–control study. European Journal of Endocrinology. 2010; 162: 153-60.
  • Berker D, Ozuguz U, Isik S, Aydin Y, Ates Tutuncu Y, Akbaba G. A report of ten patients with thyroid hemiagenesis: ultrasound screening in patients with thyroid disease. Swiss Medical Weekly. 2010; 140(7): 118-21.
  • Nsame D, Chadli A, Hallab L, El Aziz S, El Ghomari H, Farouqi A. Thyroid Hemiagenesis Associated with Hashimoto’s Thyroiditis. Case Reports in Endocrinology. 2013; 2013: 414506. doi: 10.1155/2013/414506.
  • Wang J, Gao L, Song C. Thyroid hemiagenesis associated with medullary or papillary carcinoma: Report of Cases. Head and Neck. 2014; 36: 106-11.
  • Yeh LS-T, Wang C-Y. Thyroid Hemiagenesis in a Euthyroid man. Journal of Medical Ultrasound. 2010; 18: 79-80.
  • Cakir M, Gonen S, Dikbas O, Ozturk B. Thyroid hemiagenesis with Graves' disease, Graves' ophthalmopathy and multinodular goiter. Internal Medicine. 2009; 48: 1047-9.
  • Vayisoglu Y, Ozcan C, Gen R, Eti CM, Sut H, Gorur K. Thyroid isthmus agenesis associated with thyroid papillary carcinoroid isthmus agenesis associated with thyroid papillary carcinoma. Journal of Craniofacial Surgery. 2013; 24: 428-9.
  • Kocael PÇ, Hepgül GE, Öztürk T, Cihan A. Tiroid cerrahisinde Bağcılar Eğitim Araştırma Hastanesi deneyimimiz. Endokrinolojide Diyalog Dergisi. 2010; 7(2): 63-67.
  • Ferrari CC, Lorenz K, Dionigi G, Dralle H. Surgical strategy for primary hyperparathyreoidism with thyroid hemiagenesis. Langenbeck's Archives of Surgery. 2014; 399: 1077-81.
  • Mydlarz W, Zhang K, Micchelli S, Kim M, Tufano R. Ipsilateral double parathyroid adenoma and thyroid hemiagenesis ORL. 2010; 72: 272-4.
  • Isreb S, Alem F, Smith D. Left thyroid hemiagenesis in a patient with primary hyperparathyroidism. BMJ Case Reports. 2010; 2010: bcr0320102864.
Year 2015, , 46 - 50, 05.01.2016
https://doi.org/10.24938/kutfd.124930

Abstract

References

  • Brunicandi FC, Billiar TR, Dunn DL, Hunter JG, Matthews JB, Pollock RE. Schwartz’s Principles of Surgery. 10th ed. McGraw-Hill Inc, 2014: 1688-90.
  • Bhartiya S, Verma A, Basu S, Shukla V. Congenital thyroid hemiagenesis with multinodular goiter. Acta Radiologica Short Reports. 2014; 3: 2047981614530286.
  • Ranade A, Rai R, Pai M, Nayak S, Krisnamurthy A, Narayana S. Anatomical variations of the thyroid gland: possible surgical implications. Singapore Medical Journal. 2008; 49(10): 831-4.
  • Velayutham K, Mahadevan S, Velayutham L, Jayapaul M, Appakalai B, Kannan A. A case of hemiagenesis of thyroid with double ectopic thyroid tissue. Indian Journal of Endocrinology and Metabolism. 2013; 17(4): 756-8.
  • Kroeker TR, Stancoven KM, Preskitt JT. Parathyroid adenoma on the ipsilateral side of thyroid hemiagenesis. Proceedings (Baylor University Medical Center). 2011; 24(2): 92-3.
  • Wu Y-HE, Wein RO, Carter B. Thyroid hemiagenesis: a case series and review of the literature. American Journal of Otolaryngology. 2012; 33: 299-302.
  • Chang J, Gerscovich EO, Dublin AB, McGahan JP. Thyroid hemiagenesis: a rare finding. Journal of Ultrasound in Medicine. 2011; 30: 1309-10.
  • Szczepanek-Parulska E, Szaflarski W, Piątek K, Budny B, Jaszczyńska-Nowinka K, Biczysko M. Alternative 3’acceptor site in the exon 2 of human PAX8 gene resulting in the expression of unknown mRNA variant found in thyroid hemiagenesis and some types of cancers. Acta Biochimica Polonica. 2013; 60: 573-8.
  • Oruci M, Ito Y, Buta M, Radisavljevic Z, Pupic G, Djurisic I, et al. Right thyroid hemiagenesis with adenoma and hyperplasia of parathyroid glands-case report. BMC Endocrine Disorders. 2012; 12: 29 doi: 10.1186/1472-6823-12-29.
  • Ruchala M, Szczepanek E, Szaflarski W, Moczko J, Czarnywojtek A, Pietz L. Increased risk of thyroid pathology in patients with thyroid hemiagenesis: results of a large cohort case–control study. European Journal of Endocrinology. 2010; 162: 153-60.
  • Berker D, Ozuguz U, Isik S, Aydin Y, Ates Tutuncu Y, Akbaba G. A report of ten patients with thyroid hemiagenesis: ultrasound screening in patients with thyroid disease. Swiss Medical Weekly. 2010; 140(7): 118-21.
  • Nsame D, Chadli A, Hallab L, El Aziz S, El Ghomari H, Farouqi A. Thyroid Hemiagenesis Associated with Hashimoto’s Thyroiditis. Case Reports in Endocrinology. 2013; 2013: 414506. doi: 10.1155/2013/414506.
  • Wang J, Gao L, Song C. Thyroid hemiagenesis associated with medullary or papillary carcinoma: Report of Cases. Head and Neck. 2014; 36: 106-11.
  • Yeh LS-T, Wang C-Y. Thyroid Hemiagenesis in a Euthyroid man. Journal of Medical Ultrasound. 2010; 18: 79-80.
  • Cakir M, Gonen S, Dikbas O, Ozturk B. Thyroid hemiagenesis with Graves' disease, Graves' ophthalmopathy and multinodular goiter. Internal Medicine. 2009; 48: 1047-9.
  • Vayisoglu Y, Ozcan C, Gen R, Eti CM, Sut H, Gorur K. Thyroid isthmus agenesis associated with thyroid papillary carcinoroid isthmus agenesis associated with thyroid papillary carcinoma. Journal of Craniofacial Surgery. 2013; 24: 428-9.
  • Kocael PÇ, Hepgül GE, Öztürk T, Cihan A. Tiroid cerrahisinde Bağcılar Eğitim Araştırma Hastanesi deneyimimiz. Endokrinolojide Diyalog Dergisi. 2010; 7(2): 63-67.
  • Ferrari CC, Lorenz K, Dionigi G, Dralle H. Surgical strategy for primary hyperparathyreoidism with thyroid hemiagenesis. Langenbeck's Archives of Surgery. 2014; 399: 1077-81.
  • Mydlarz W, Zhang K, Micchelli S, Kim M, Tufano R. Ipsilateral double parathyroid adenoma and thyroid hemiagenesis ORL. 2010; 72: 272-4.
  • Isreb S, Alem F, Smith D. Left thyroid hemiagenesis in a patient with primary hyperparathyroidism. BMJ Case Reports. 2010; 2010: bcr0320102864.
There are 20 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Ahmet Kocael

Anıl Orhan This is me

Betül Vatankulu This is me

Gülçin Ercan This is me

Zekeriya Karaduman This is me

Pınar Kocael This is me

Kenan Ulualp This is me

Publication Date January 5, 2016
Submission Date January 5, 2016
Published in Issue Year 2015

Cite

APA Kocael, A., Orhan, A., Vatankulu, B., Ercan, G., et al. (2016). Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi. The Journal of Kırıkkale University Faculty of Medicine, 17(3), 46-50. https://doi.org/10.24938/kutfd.124930
AMA Kocael A, Orhan A, Vatankulu B, Ercan G, Karaduman Z, Kocael P, Ulualp K. Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi. Kırıkkale Üni Tıp Derg. January 2016;17(3):46-50. doi:10.24938/kutfd.124930
Chicago Kocael, Ahmet, Anıl Orhan, Betül Vatankulu, Gülçin Ercan, Zekeriya Karaduman, Pınar Kocael, and Kenan Ulualp. “Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi”. The Journal of Kırıkkale University Faculty of Medicine 17, no. 3 (January 2016): 46-50. https://doi.org/10.24938/kutfd.124930.
EndNote Kocael A, Orhan A, Vatankulu B, Ercan G, Karaduman Z, Kocael P, Ulualp K (January 1, 2016) Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi. The Journal of Kırıkkale University Faculty of Medicine 17 3 46–50.
IEEE A. Kocael, A. Orhan, B. Vatankulu, G. Ercan, Z. Karaduman, P. Kocael, and K. Ulualp, “Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi”, Kırıkkale Üni Tıp Derg, vol. 17, no. 3, pp. 46–50, 2016, doi: 10.24938/kutfd.124930.
ISNAD Kocael, Ahmet et al. “Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi”. The Journal of Kırıkkale University Faculty of Medicine 17/3 (January 2016), 46-50. https://doi.org/10.24938/kutfd.124930.
JAMA Kocael A, Orhan A, Vatankulu B, Ercan G, Karaduman Z, Kocael P, Ulualp K. Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi. Kırıkkale Üni Tıp Derg. 2016;17:46–50.
MLA Kocael, Ahmet et al. “Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi”. The Journal of Kırıkkale University Faculty of Medicine, vol. 17, no. 3, 2016, pp. 46-50, doi:10.24938/kutfd.124930.
Vancouver Kocael A, Orhan A, Vatankulu B, Ercan G, Karaduman Z, Kocael P, Ulualp K. Multinodüler Guatrlı Bir Olguda Tiroid Hemiagenezi. Kırıkkale Üni Tıp Derg. 2016;17(3):46-50.

Bu Dergi, Kırıkkale Üniversitesi Tıp Fakültesi Yayınıdır.