Preoperative Approach to Hereditary Angioedema Patients in Two Cases

Year 2018, , 221 - 225, 31.08.2018

Hülya Nazik , Perihan Öztürk , Mehmet Kamil Mülayim , İnci Dalyan

https://doi.org/10.24938/kutfd.341226

Abstract

Our aim is
to draw attention to the importance of prophylactic treatment in preoperative,
perioperative and postoperative period for hereditary angioedema patients for
whom minor or major surgery is planned. Two patients with a diagnosis of
hereditary angioedema were treated with 1000 IU C1 esterase inhibitor 1-6 hours
before minor surgery. Case 1 did not develop an attack during the procedure and
within postoperative one month. In case 2 with incomplete lupus erythematosus,
angioedema occurred in the lips one hour after the procedure. One more dose of
C1 esterase inhibitor was administered to the patient and angioedema was
delayed within half an hour. In this study, it was aimed to emphasize the
importance of prophylactic treatment to prevent attack development during the
procedure in patients with hereditary angioedema.

Keywords

Hereditary angioedema, prophylaxis, C1 esterase inhibitor

İKİ OLGU İLE HEREDİTER ANJİYOÖDEMLİ HASTALARA PREOPERATİF YAKLAŞIMIN GÖZDEN GEÇİRİLMESİ

Abstract

Küçük veya
büyük cerrahi işlem planlanan herediter anjiyoödem olguları için preoperatif
dönemde proflaktik tedavinin önemi, perioperatif ve postoperatif dönemde
karşılaşılabilecek sorunlar konusuna dikkat çekilmesi amaçlanmıştır. Herediter
anjiyoödem tanısı ile takibi süren 2 olguya minör cerrahi işlemden 1-6 saat
önce 1000 IU C1 esteraz inhibitörü uygulandı. Olgu 1'de işlem sırasında ve
sonraki bir ayda atak gelişmedi. İnkomplet lupus eritematozusu olan olgu 2’de
ise işlemden bir saat sonra dudakta anjiyoödem ortaya çıktı. Hastaya bir doz
daha C1 esteraz inhibitörü verildi ve anjiyoödem yarım saat içinde geriledi. Bu
çalışmada herediter anjiyoödemli hastalarda işlem sırasında atak gelişimine
engel olmak için proflaktik tedavinin önemine dikkat çekilmesi amaçlanmıştır.

Keywords

proflaksi, Herediter anjiyoödem, C1 esteraz inhibitörü

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