FIRST CASE OF ENZOOTIC NASAL ADENOCARCINOMA (ENA) IN A SHEEP IN TURKEY

Year 2016, Volume: 1 Issue: 1, 87 - 90, 23.06.2016

Özlem Özmen , Nilay Serpin

https://doi.org/10.24880/maeuvfd.260794

Cited By: 3

Abstract

Abstract: A 2-year-old sheep presented with complains of nasal discharge and respiratory distress from a flock consisting 125 animals. Owner stated that the ewe started having clear nasal discharge more than three months and 15 sheep died with similar clinical symptoms in 3 years of period. During the clinical examination, depression and inappetence were observed to the sheep. Because of poor prognosis the ewe was euthanatized. At necropsy, bilateral tumors were seen in nasal cavity. Masses were soft, pinkish color, covered by mucinous exudate and completely filled the nasal cavity, invasion to the nasal sinuses were observed. The tumors localized in the right and left side of nasal cavity were 4,5x4x2 cm and 9,5x10x4 cm in diameters respectively. At the histopathological examination, the mass consisted of well-differentiated cuboidal to columnar cells with moderate amount of eosinophilic cytoplasm and round to oval nuclei. According to clinical and pathological findings the mass diagnosed as Enzootic Nasal Adenocarcinoma. This is the first Enzootic Nasal Adenocarcinoma report in a sheep in Turkey.

Keywords

Enzootik Nasal Adenokarcinom, Koyun, Patoloji

References

• References
• De las Heras M, Garcia de Jalon JA, Balaguer L, Badiola JJ. Pathology of enzootic nasal tumor in thirty-eight goats. Vet Pathol. 1991; 28: 474-481.
• Jones TC, Hunt RD, King NW. Nasal passages and paranasal sinuses neoplasms. In: Veterinary Pathology, 6th ed. Blackwell Publishing. Iowa. 2006
• De las Heras M, Minguijon E, Ferrer LM, Ortin A, Dewar P, Cebrian LM, Pascual Z, Garcia L, Garcia de Jalon J, Sharp JM. Naturally occurring enzootic nasal tumor of sheep in Spain: pathology and associated retrovirus. Eur J Vet Pathol. 1998;4: 11–16.
• Lopez A. Respiratory system. In: Carlton WW, McGavin MD, Zachary JF (Eds.) Thomson’s Special Pathology, 3rd ed, Mosby-Year Book Inc, Missouri. 2001
• De las Heras M, Ortin A, Cousens C, Minguijon E, Sharp JM. Enzootic nasal adenocarcinoma of sheep and goats. Curr Top Microbiol Immunol. 2003; 275: 201–223.
• McKinnon AO, Thorsen J, Hayes MA, Misener CR. Enzootic nasal adenocarcinoma of sheep in Canada. Can Vet J. 1982; 23: 88–94.
• Duncan JR, Tayler DE, Van der Maaten MJ, Andersen JR. Enzootic nasal adenocarcinoma in sheep. JAVMA. 1967; 151,732-734.
• Svara T, Gombac M, Vrecl M, Jntes P, Kostanjsek R, Pogacnic R, Pogacnik M. Enzootic nasal adenocarcinoma of sheep in Slovenia. J Vet Med A. 2006; 53: 26-29.
• Ozmen O, Sahinduran S, Haligur M, Demir N. Clinical, pathological, immunohistochemical and ultrastructural observations on Enzootic Nasal Adenocarcinoma in five goats. Kafkas Univ Vet Fak Derg. 2010; 16(4): 633-639.
• Palmarini M, Mughetti L, Tollis M, Alunni L, Vitellozzi G. Il tumore intranasale enzootico della capra. Summa. 1994; 3: 49–53.
• Wilson DW, Dungworth DL. Tumors of the respiratory tract. In: Meuten DJ (Ed), Tumors in the Domestic Animals, 4th ed. Iowa State Press, Iowa. 2002