Antipsikotikler ve Antidepresanlar Aort Diseksiyonlarının Oluşumunu veya Kronikleşmesini Etkileyebilir mi?

Abstract

Akut Stanford tip-A aort diseksiyonları(STAAD), aort rüptürü, ciddi aort kapak yetmezliği, perikardiyal tamponad ve serebral ve/veya koroner malperfüzyon risklerini ortadan kaldırmak için acil cerrahi gerektiren, hayatı tehdit edici hastalıklardır. Sadece küçük bir hasta alt grubu fark edilmez ve belirsiz mekanizma ile kronikleşir. Bu hastalar genellikle geç semptomlar yüzünden veya tesadüfen teşhis edilir. Kardiyopulmoner bypass ve bazen derin hipotermi ve sikülatuvar arrest gerektiren cerrahi teknikler, önemli mortalite ve komplikasyonları olan ilk basamak tedavilerdir. Burada, antipsikotik ve antidepresan tedavi alan ve total aortik ark replasmanı ile başarıyla onarılan tanısı tesadüfen konulmuş kronik STAAD hastası sunulmuştur

Keywords

• Kronik aort diseksiyonu
• Kan basıncı
• Antipsikotikler
• Antidepresanlar
• Cerrahi

Can Antipsychotics and Antidepressants Affect the Formation or Chronicization of Aortic Dissections?

Abstract

Acute Stanford type-A aortic dissections (STAAD) are life-threatening diseases which require emergency surgery to eliminate risks of aortic rupture, severe aortic valve insufficiency, pericardial tamponade and cerebral and/or coronary malperfusion. Only a small subset of patients go unnoticed and become chronic with unclear mechanism. These patients are usually diagnosed thru late symptoms or incidentally. Surgical techniques requiring cardiopulmonary bypass and sometimes deep hypothermia and circulatory arrest are first-line treatments with considerable mortality and complications. Herein, an incidentally diagnosed chronic STAAD patient who was receiving antipsychotic and antidepressant treatment and successfully repaired with total aortic arch replacement was presented.

Keywords

• Chronic aortic dissection
• Blood pressure
• Antipsychotics
• Antidepressants
• Surgery

References

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