EN
TR
Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-ray Images
Abstract
Pneumonia is one of the major infectious diseases leading to death worldwide and its early detection is crucial for successful treatment. Chest X-ray images are a frequently used method for the detection of pneumonia and often contain complex structures to make an accurate diagnosis. In this study, deep learning based models are used to classify normal and pneumonia labeled data in Chest X-ray images. As a result of the comparisons made on MobileNetV2, ResNet50, VGG19, Xception and ViT models, the VGG19 model achieved the highest success with an accuracy of 88.14%. In addition, the proposed hybrid activation function integrated into the VGG19 model performed the best with 91.67% accuracy and improved the classification success. Performance evaluations with the integration of different loss functions (MSE, MAE, Binary Cross-Entropy and the proposed loss function) also revealed that the Proposed Hybrid loss function achieved the highest performance with 92.63% accuracy. These findings show that hybrid activation and loss functions significantly improve classification accuracy in deep learning-based medical imaging applications.
Keywords
Ethical Statement
All data used in this study are taken from a publicly available and freely accessible dataset. Therefore, there is no requirement for an ethical declaration. The dataset is obtained from open sources provided for research purposes and does not contain any personal data.
References
- [1] Ruuskanen, O., Lahti, E., Jennings, L. C., & Murdoch, D. R. (2011). Viral pneumonia. The Lancet, 377(9773), 1264-1275.
- [2] Hammoudi, K., Benhabiles, H., Melkemi, M., Dornaika, F., Arganda-Carreras, I., Collard, D., & Scherpereel, A. (2021). Deep learning on chest X-ray images to detect and evaluate pneumonia cases at the era of COVID-19. Journal of medical systems, 45(7), 75.
- [3] MacMahon, H. (2003). Digital chest radiography: practical issues. Journal of thoracic imaging, 18(3), 138-147.
- [4] Rajpurkar, P. (2017). CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning. ArXiv abs/1711, 5225.
- [5] Pan, S. J., & Yang, Q. (2009). A survey on transfer learning. IEEE Transactions on knowledge and data engineering, 22(10), 1345-1359.
- [6] Khan, E., Rehman, M. Z. U., Ahmed, F., Alfouzan, F. A., Alzahrani, N. M., & Ahmad, J. (2022). Chest X-ray classification for the detection of COVID-19 using deep learning techniques. Sensors, 22(3), 1211.
- [7] Shelke, A., Inamdar, M., Shah, V., Tiwari, A., Hussain, A., Chafekar, T., & Mehendale, N. (2021). Chest X-ray classification using deep learning for automated COVID-19 screening. SN computer science, 2(4), 300.
- [8] Ibrahim, A. U., Ozsoz, M., Serte, S., Al-Turjman, F., & Yakoi, P. S. (2024). Pneumonia classification using deep learning from chest X-ray images during COVID-19. Cognitive computation, 16(4), 1589-1601.
Details
Primary Language
English
Subjects
Software Engineering (Other)
Journal Section
Research Article
Early Pub Date
June 24, 2025
Publication Date
June 30, 2025
Submission Date
January 22, 2025
Acceptance Date
April 22, 2025
Published in Issue
Year 2025 Volume: 13 Number: 1
APA
Özkan, Y., & Barin Özkan, S. (2025). Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-ray Images. Mus Alparslan University Journal of Science, 13(1), 15-25. https://doi.org/10.18586/msufbd.1625377
AMA
1.Özkan Y, Barin Özkan S. Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-ray Images. Mus Alparslan University Journal of Science. 2025;13(1):15-25. doi:10.18586/msufbd.1625377
Chicago
Özkan, Yasin, and Sibel Barin Özkan. 2025. “Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-Ray Images”. Mus Alparslan University Journal of Science 13 (1): 15-25. https://doi.org/10.18586/msufbd.1625377.
EndNote
Özkan Y, Barin Özkan S (June 1, 2025) Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-ray Images. Mus Alparslan University Journal of Science 13 1 15–25.
IEEE
[1]Y. Özkan and S. Barin Özkan, “Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-ray Images”, Mus Alparslan University Journal of Science, vol. 13, no. 1, pp. 15–25, June 2025, doi: 10.18586/msufbd.1625377.
ISNAD
Özkan, Yasin - Barin Özkan, Sibel. “Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-Ray Images”. Mus Alparslan University Journal of Science 13/1 (June 1, 2025): 15-25. https://doi.org/10.18586/msufbd.1625377.
JAMA
1.Özkan Y, Barin Özkan S. Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-ray Images. Mus Alparslan University Journal of Science. 2025;13:15–25.
MLA
Özkan, Yasin, and Sibel Barin Özkan. “Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-Ray Images”. Mus Alparslan University Journal of Science, vol. 13, no. 1, June 2025, pp. 15-25, doi:10.18586/msufbd.1625377.
Vancouver
1.Yasin Özkan, Sibel Barin Özkan. Effect of Hybrid Activation and Loss Functions for Pneumonia Classification in Chest X-ray Images. Mus Alparslan University Journal of Science. 2025 Jun. 1;13(1):15-2. doi:10.18586/msufbd.1625377