LEPTİN VE ADİPONEKTİNİN ENERJİ VE EGZERSİZ İLİŞKİSİ

Year 2017, , 166 - 174, 01.07.2017

Duygu Dalğın Musa Çon , Metin Çenesiz , Sena Çenesiz

https://doi.org/10.17155/omuspd.305531

Abstract

Dünya sağlık örgütünün
belirlemelerine göre gıda çeşitliliği ve alımının kolaylaşması ile birlikte
yaşam tarzındaki değişikliler 1980 yılından itibaren obezite insidansını iki
katına çıkartmıştır. Obezite de beraberinde kalp damar hastalıklarından, tip II
diabete ve ortopedik hastalıklara kadar birçok sağlık sorununu beraberinde
getirmektedir. Bu sorunlarla birlikte bu durumdan kurtulmak için yeni arayışlar
içine girilmektedir. Egzersizle birlikte vücutta salgılanan hormonlar ve
proteinler daha fazla araştırma konusu haline gelmiştir.

Trigliseritlerin deposu olarak
görülen adipoz doku üzerine yapılan çalışmalar arttıkça bunların bilinmeyen
birçok fizyolojik görevlerinin olduğu ortaya çıkmaktadır. Bunlardan leptin ve
adiponektin gibi hormonların enerji dengesi ve insulin direnci ile ilgili
bağlantıları yapılan çalışmalarla ortaya konulmaktadır. Leptin organizma
içindeki yağ stoklarını ve iştahı düzenlemekte, tokluk duygusu yaratmaktadır.
Vücuttaki yağ oranı leptin salınmasını doğrudan etkilemektedir. Adiponektin de
adipoz dokudan salınan, insulin duyarlılığını artıran, aterosklerozu gerileten,
anti-enflamatuar bir hormondur. Her iki hormonunda plazma seviyesi cinsiyet,
yaşam şekli ve yaş gibi etkenlerden etkilenebilmektedir. Kısa süreli
egzersizlerde değişim ya hiç ya da çok az olmakla birlikte esas uzun süreli
yapılan egzersizlerde bu hormonlarda plazma seviyelerinde değişim
gözlenmektedir. Yapılan bu derleme ile bu iki hormonun egzersiz ve enerji
dengesi ile ilişkileri ortaya konulacaktır.

Keywords

Adiponektin, Egzersiz, leptin

THE ASSOCIATION OF LEPTIN AND ADIPONECTIN WITH ENERGY AND EXERCISE

Abstract

This study will
present the association of leptin and adiponectin hormones with exercise and
energy balance in the light of literature.

As studies on adipose
tissue, known as the repository of triglycerides, increase, it is revealed that
they have many physiologic functions unknown previously. Studies conducted
demonstrate the correlation between leptin and adiponectin hormones with energy
balance and insulin resistance. Leptin regulates fat supply and appetite in
organism and creates the feeling of being full. Fat ratio in the body directly
affects leptin secretion. Adiponectin is an anti-inflammatory hormone secreted
from adipose tissue which enhances insulin susceptibility and downgrades
atherosclerosis. Plasma levels of both hormones are affected by factors like
gender, lifestyle and age. It has been concluded that short duration exercises
have little or no effect on plasma levels of these hormones, while long
duration exercises create significant effects. Long duration exercises have
been recommended to fight insulin resistance, diabetes, hypertension, obesity,
excessive weight and for positive effect on energy balance.

Keywords

Adiponectin, Exercise, Leptin

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