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NADIR BIR OLGU; ANTIKOAGÜLAN TEDAVININ TETIKLEDIĞI SAFRA KESESI KANAMASI – İKTER

Year 2016, Volume: 38 Issue: 3, 63 - 65, 26.04.2016

Abstract

ÖZET:
Antikoagülan tedavi, klinik açıdan geniş bir spektrum oluşturan tromboembolik
hastalıkların profilaksi ve tedavisinde yaşamsal önem taşıyan, ileri kardiyak
cerrahi operasyonlar sonrası kullanımı zorunlu olan bir tedavi yöntemidir. Bu
tedavinin tromboz veya kanamaya yol açmayacak şekilde planlanması, klinik ve
laboratuvar takibinin titizlikle yapılması oldukça önem taşımaktadır. Oral
antikoagülanlara bağlı hemobilia (safra kesesi içine kanama) çok nadir
görülmektedir. Hemobilia; cerrahi travmayı takiben, karaciğer biyopsisi
sonrası, anevrizmalar, extra veya intrahepatik safra yolu tümörleri, safra
taşları ve karaciğerin özellikle parazitik ve pyojenik inflamatuar lezyonları
nedeniyle oluşabilen safra yollarına doğru olan kanamadır. Bu sunumda aort
kapak replasmanı (AVR) ve atrial fibrilasyon (AF) nedeniyle profilaktik olarak
warfarin alımına bağlı spontan safra kesesi kanaması gelişen bir olgu
sunulmuştur.

ANAHTAR
KELIMELER: warfarin,hemobilia,profilaktik,spontan


A
RARE CASE; ANTICOAGULANT THERAPY INDUCED GALLBLADDER 
HEMORRHAGE-JAUNDICE

ABSTRACT:
Anticoagulant therapy is a vital method of treatment and prophylaxis of
thromboembolic diseases which clinically have a wide spectrum, and essential
after cardiac valve surgery. Therefore, it is vital that anticoagulant therapy be
planned so that it does not lead to thrombosis or bleeding and clinical and
laboratory follow-up should be performed carefully. Gallbladder (GB) hemorrhage
(hemobilia) is a rare occurence during standard anticoagulation therapy.
Hemobilia is a hemorrhage
  into the
biliary tract that may follow surgical trauma, liver biopsy, aneurysms,
extra-intrahepatic tumors of the biliary tract, gallstones, and inflammatory
lesions of liver, especially helmintic or pyogenic. In this
  article, a case, who developed hemobilia
caused by requiring warfarin as prophylaxis because of aortic valve replacement
(AVR) and atrial fibrillation, was presented.















KEY WORDS: Warfarin,
hemobilia,prophylactic, spontaneous

References

  • 1. Hong, J. W., Han, Y. S., Lee, J. H., Kim, N. H., Lim, K. W., Joung, Y. H., & Lee, J. I. (2004). [A case of non-traumatic hemobilia due to warfarin therapy].The Korean journal of gastroenterology= Taehan Sohwagi Hakhoe chi, 44(5), 292-295.
  • 2. Sandblom, P. (1948). Hemorrhage into the biliary tract following trauma; traumatic hemobilia. Surgery, 24(3), 571-586.
  • 3. Pollack, B. J., Chak, A., Dahman, B., & Sivak, M. V. (1997). Warfarin therapy complicated by recurrent hemobilia in a patient with sarcoidosis.Gastrointestinal endoscopy, 46(1), 72-76.
  • 4. Shoeb, M., & Fang, M. C. (2013). Assessing bleeding risk in patients taking anticoagulants. Journal of thrombosis and thrombolysis, 35(3), 312-319.
  • 5. Hahn YS, Lee HK. (1976) Traumatic hemobilia following blunt chest trauma. Korean J Thoracic Cardiovasc Surg. 9:117-24.
  • 6. Ehrman, J. K., Gordon, P. M., Visich, P. S., & Keteyian, S. J. (2013). Clinical exercise physiology. Human Kinetics
  • 7. Kim, K. H., & Kim, T. N. (2012). Etiology, clinical features, and endoscopic management of hemobilia: a retrospective analysis of 37 cases. The Korean Journal of Gastroenterology, 59(4), 296-302.
  • 8. Levine, M. N., Raskob, G., Beyth, R. J., Kearon, C., & Schulman, S. (2004). Hemorrhagic complications of anticoagulant treatment: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. CHEST Journal,126(3_suppl), 287S-310S.
  • 9. Hart, R. G., Pearce, L. A., & Aguilar, M. M. (2007). Adjusted-dose warfarin versus aspirin for preventing stroke in patients with atrial fibrillation. Annals of internal medicine, 147(8), 590-592.
  • 10. Polat, C., Dervisoglu, A., Guven, H., Kaya, E., Malazgirt, Z., Danaci, M., & Ozkan, K. (2003). Anticoagulant-induced intramural intestinal hematoma. The American journal of emergency medicine, 21(3),208-211.
Year 2016, Volume: 38 Issue: 3, 63 - 65, 26.04.2016

Abstract

References

  • 1. Hong, J. W., Han, Y. S., Lee, J. H., Kim, N. H., Lim, K. W., Joung, Y. H., & Lee, J. I. (2004). [A case of non-traumatic hemobilia due to warfarin therapy].The Korean journal of gastroenterology= Taehan Sohwagi Hakhoe chi, 44(5), 292-295.
  • 2. Sandblom, P. (1948). Hemorrhage into the biliary tract following trauma; traumatic hemobilia. Surgery, 24(3), 571-586.
  • 3. Pollack, B. J., Chak, A., Dahman, B., & Sivak, M. V. (1997). Warfarin therapy complicated by recurrent hemobilia in a patient with sarcoidosis.Gastrointestinal endoscopy, 46(1), 72-76.
  • 4. Shoeb, M., & Fang, M. C. (2013). Assessing bleeding risk in patients taking anticoagulants. Journal of thrombosis and thrombolysis, 35(3), 312-319.
  • 5. Hahn YS, Lee HK. (1976) Traumatic hemobilia following blunt chest trauma. Korean J Thoracic Cardiovasc Surg. 9:117-24.
  • 6. Ehrman, J. K., Gordon, P. M., Visich, P. S., & Keteyian, S. J. (2013). Clinical exercise physiology. Human Kinetics
  • 7. Kim, K. H., & Kim, T. N. (2012). Etiology, clinical features, and endoscopic management of hemobilia: a retrospective analysis of 37 cases. The Korean Journal of Gastroenterology, 59(4), 296-302.
  • 8. Levine, M. N., Raskob, G., Beyth, R. J., Kearon, C., & Schulman, S. (2004). Hemorrhagic complications of anticoagulant treatment: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. CHEST Journal,126(3_suppl), 287S-310S.
  • 9. Hart, R. G., Pearce, L. A., & Aguilar, M. M. (2007). Adjusted-dose warfarin versus aspirin for preventing stroke in patients with atrial fibrillation. Annals of internal medicine, 147(8), 590-592.
  • 10. Polat, C., Dervisoglu, A., Guven, H., Kaya, E., Malazgirt, Z., Danaci, M., & Ozkan, K. (2003). Anticoagulant-induced intramural intestinal hematoma. The American journal of emergency medicine, 21(3),208-211.
There are 10 citations in total.

Details

Subjects Health Care Administration
Journal Section OLGU SUNUMU
Authors

Bartu Badak

Güvenç Diner This is me

Publication Date April 26, 2016
Published in Issue Year 2016 Volume: 38 Issue: 3

Cite

Vancouver Badak B, Diner G. NADIR BIR OLGU; ANTIKOAGÜLAN TEDAVININ TETIKLEDIĞI SAFRA KESESI KANAMASI – İKTER. Osmangazi Tıp Dergisi. 2016;38(3):63-5.


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