Evaluation of Inflammation Markers in Elderly Patients Undergoing Hip Fracture Surgery

Abstract

Objectives: High inflammatory markers are thought to be important in evaluating poor postoperative outcomes in older orthopedic patients. We aim to investigate the effect of inflammatory markers in patients over 80 who have undergone a hip fracture surgery regarding 30-day mortality and preoperative evaluation. Materials and Methods: Patients over 80 who had undergone hip fracture surgery were included. Age, gender, type of anesthesia, comorbidities, anticoagulant, intensive care unit (ICU) admission, hospitalization period, 30-day mortality rates, were recorded and platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR) and systemic immune inflammation index (SII) values were calculated. Results: The mean age was 85.48±4.07 years old. Postoperative ICU admission was found to be 41.1%, and the 30-day mortality rate was 3.3%. The PLR value was 191±105, the NLR value was 6.4±4.5, and the SII value was 1410±1210. A significant correlation was found between ICU hospitalization and mortality, preoperative and postoperative hospital stay. Conclusion: While there was a positive correlation between intensive care hospitalization and mortality, although no statistically significant correlation was found between the PLR, NLR and SII values and mortality rates, high values close to those stated in the literature were found.

Keywords

• Anesthesia
• hip fracture
• inflammation marker
• intensive care unit admission
• mortality

Kalça Kırığı Cerrahisi Geçiren Yaşlı Hastalarda İnflamasyon Belirteçlerinin Değerlendirilmesi

Öz

Amaç: İleri yaş ortopedik hastalarda yüksek inflamatuar belirteçlerin kötü postoperatif sonuçların değerlendirilmesinde önemli olduğu düşünülmektedir. Amacımız 80 yaş üstü kalça kırığı ameliyatı geçirmiş hastalarda 30 günlük mortalite ve ameliyat öncesi değerlendirme açısından inflamatuar belirteçlerin etkisini araştırmaktır. Materyal ve Metot: Kalça kırığı ameliyatı geçiren 80 yaş üstü hastalar çalışmaya dahil edildi. Yaş, cinsiyet, anestezi türü, komorbiditeler, antikoagülan kullanımı, yoğun bakım ünitesinde (YBÜ) yatış süresi, hastane yatış süresi, 30 günlük mortalite oranları kaydedilerek trombosit/lenfosit oranı (PLR), nötrofil/lenfosit oranı (NLR) ve sistemik immun inflamasyon indeksi (SII) değerleri hesaplandı. Bulgular: Yaş ortalaması 85,48 ± 4,07 idi. Postoperatif YBÜ yatışı % 41,1 idi ve 30 günlük mortalite oranı ise %3,3 idi. PLR değeri 191 ± 105, NLR değeri 6,4 ± 4,5, SII değeri ise 1410 ± 1210 olarak saptandı. YBÜ yatışı ile mortalite, preoperatif ve postoperatif yatış süreleri arasında anlamlı korelasyon saptandı. Sonuç: Yoğun bakıma yatış ile mortalite arasında pozitif bir ilişki bulunurken, PLR, NLR ve SII değerleri ile mortalite oranları arasında istatistiksel olarak anlamlı bir ilişki bulunmamasına rağmen literatürde belirtilen değerlere yakın yüksek değerler bulunmuştur.

Anahtar Kelimeler

• Anestezi
• inflamasyon belirteci
• kalça kırığı
• mortalite
• yoğun bakım yatışı

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