Research Article
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The Evaluation of Sleep Quality and Voiding Function in Children with Obesity

Year 2022, Volume: 7 Issue: 3, 446 - 452, 01.09.2022
https://doi.org/10.26453/otjhs.1075795

Abstract

Objective: Obesity is an important health problem with the potential to cause secondary diseases in children. In these patients, increased intra-abdominal and intra-vesical pressure leads to changes in voiding physiology. In addition, insulin and glucose metabolism disorders can also affect lower urinary system functions. However, the relationship between obesity and sleep disorders is also known.
Materials and Methods: The questionnaire, which was prepared to determine voiding and sleep disorders, was applied to 100 obese pediatric patients aged between 9 and 18 and 100 normal weight healthy individuals in the similar age group.
Results: Daytime urinary incontinence was present in 17% of the patient group and 2% of the control group. Nocturnal enuresis was present in 25% of the patient group and 2% of the control group. The frequency of overactive bladder was also higher in the patient group compared to the healthy controls (15% and 5%, respectively; p<0.05). In addition, a higher rate of restless sleep at night, snoring and tiredness during the day were determined in the patient group. However, significantly increased behavioral disorders and learning disabilities were found in this group.
Conclusion: This is the first study to show a higher prevalence of decreased sleep quality and voiding dysfunction in obese children compared to the healthy group. Pathologies that occur due to the negative effects of obesity on many systems reveal the necessity of evaluating the disease as a syndrome in childhood. Multidisciplinary approach will increase the success of treatment in these patients. 

References

  • Kohut T, Robbins J, Panganiban J. Update on childhood/adolescent obesity and its sequela. Curr Opin Pediatr. 2019;31(5):645-653. doi:10.1097/MOP.0000000000000786
  • Kyle TK, Dhurandhar EJ, Allison DB. Regarding obesity as a disease: evolving policies and their implications. Endocrinol Metab Clin North Am. 2016;45(3):511-20. doi:10.1016/j.ecl.2016.04.004
  • Gkalonaki I, Patoulias I. Dysfunctional elimination syndrome: a short review of the literature. Folia Med Cracov. 2021;61(2):79-90. doi: 10.24425/fmc.2021.137225
  • Fuselier A, Hanberry J, Margaret Lovin J, Gomelsky A. Obesity and stress urinary ıncontinence: ımpact on pathophysiology and treatment. Curr Urol Rep. 2018;22;19(1):10. doi:10.1007/s11934-018-0762-7
  • Kim JK, Lee YG, Han K, Han JH. Obesity, metabolic health, and urological disorders in adults: a nationwide population-based study. Sci Rep. 2021;22;11(1):8687. doi:10.1038/s41598-021-88165-z
  • Bonnet MH, Arand DL. Clinical effects of sleep fragmentation versus sleep deprivation. Sleep Med Rev. 2003;7(4):297-310. doi:10.1053/smrv.2001.0245
  • McHill AW, Wright KP Jr. Role of sleep and circadian disruption on energy expenditure and in metabolic predisposition to human obesity and metabolic disease. Obes Rev. 2017;18;(1):15-24. doi:10.1111/obr.12503
  • Tucker KM, Ingram M, Doubleday K, Piper R, Carvajal SC. La Vida Buena (The Good Life) evaluation: a quasi experimental intervention of a community health worker-led family-based childhood obesity program for Latino children 5-8 years of age on the US-Mexico border. BMC Public Health. 2019;14;19(1):759. doi:10.1186/s12889-019-7081-x
  • Savoie MB, Lee KA, Subak LL, ve ark. Beyond the bladder: poor sleep in women with overactive bladder syndrome. Am J Obstet Gynecol. 2020;222(6):600.e1-600.e13. doi:10.1016/j.ajog.2019.12.005
  • Winkelman WD, Warsi A, Huang AJ, ve ark. Sleep quality and daytime sleepiness among women with urgency predominant urinary ıncontinence. Female Pelvic Med Reconstr Surg. 2018;24(2):76-81. doi:10.1097/SPV.0000000000000547
  • Anderson LN, Carsley S, Lebovic G, ve ark. Misclassification of child body mass index from cut-points defined by rounded percentiles instead of Z-scores. BMC Res Notes. 2017;28;10(1):639. doi:10.1186/s13104-017-2983-0
  • Abrams P, Cardozo L, Fall M, ve ark. The standardisation of terminology of lower urinary tract function. Report from the standardisation subcommittee of the International Continence Society. Neurourol Urodyn. 2002;21(2):167-78. doi: 10.1002/nau.10052
  • Thomas-Eapen N. Childhood Obesity. Prim Care. 2021;48(3):505-515. doi:10.1016/j.pop.2021.04.002
  • Gondim R, Gorjão J, Nacif A, Franco I, Barroso U Jr. Evaluation of autonomic function in children and adolescents with overactive bladder. Int Braz J Urol. 2021;47(6):1178-1188. doi:10.1590/S1677-5538.IBJU.2021.0177
  • Caldwell PH. Tips for managing treatment-resistant enuresis. J Paediatr Child Health. 2018;54(10):1060-1064. doi:10.1111/jpc.14158
  • Karmali S, Ng V, Battram D, ve ark. Coaching and/or education intervention for parents with overweight/obesity and their children: study protocol of a single-centre randomized controlled trial. BMC Public Health. 2019;28;19(1):345.doi:10.1186/s12889-019-6640-5.
  • Su MS, Xu L, Pan WF, Li CC. Current perspectives on the correlation of nocturnal enuresis with obstructive sleep apnea in children. World J Pediatr. 2019;15(2):109-116. doi:10.1007/s12519-018-0199-6
  • Fuselier A, Hanberry J, Margaret Lovin J, Gomelsky A. Obesity and stress urinary ıncontinence: ımpact on pathophysiology and treatment. Curr Urol Rep. 2018;22;19(1):10. doi:10.1007/s11934-018-0762-7
  • Smith L, Toussaint L, Micoli A, Lynch B. Obesity, putative biological mediators, and cognitive function in a national sample of children and adolescents. Prev Med. 2021;150:106659. doi:10.1016/j.ypmed.2021.106659
  • Fernández-Andújar M, Morales-García E, García-Casares N. obesity and gray matter volume assessed by neuroimaging: a systematic review. Brain Sci. 2021;28;11(8):999. doi:10.3390/brainsci11080999
  • Spiegel K, Leproult R, Colecchia EF, ve ark. Adaptation of the 24-h growth hormone profile to a state of sleep debt. Am J Physiol Regul Integr Comp Physiol. 2000;279(3):R874-83. doi:10.1152/ajpregu.2000.279.3.R874
  • Ma Y, Liang L, Zheng F, Shi L, Zhong B, Xie W. Association between sleep duration and cognitive decline. JAMA Netw Open. 2020;1;3(9):e2013573. doi:10.1001/jamanetworkopen.2020.13573

Obez Çocuklarda Uyku Kalitesi ve İşeme Fonksiyonunun Değerlendirilmesi

Year 2022, Volume: 7 Issue: 3, 446 - 452, 01.09.2022
https://doi.org/10.26453/otjhs.1075795

Abstract

Amaç: Çocuklarda obezite ikincil hastalıklara yol açabilen önemli bir sağlık sorunudur. Bu hastalarda artan intraabdominal ve intravezikal basınç işeme fizyolojisinde değişikliklere yol açar. Ayrıca insülin ve glukoz metabolizma bozukluğu da alt üriner sistem fonksiyonlarını etkileyebilmektedir. Bununla birlikte obezitenin uyku bozuklukları ile ilişkisi de bilinmektedir.
Materyal ve Metot: İşeme ve uyku bozukluklarını belirlemek için hazırlanan anket, yaşları 9 ile 18 arasında olan, 100 obez çocuk hasta ile benzer yaş grubundaki 100 normal kilolu sağlıklı bireye uygulandı.
Bulgular: Hasta grubunun %17’sinde kontrol grubunun %2’sinde gündüz idrar kaçırma şikayeti varken, nokturnal enürezis hasta grubunun %25’inde, kontrol grubunun ise %2’sinde gözlendi. Hasta grubunda sağlıklı kontrollere göre aşırı aktif mesane sıklığı da daha fazla idi (sırasıyla %15 ve %5; p<0,05). Ayrıca hasta grubunun daha yüksek oranda gece huzursuz uyuduğu, horladığı ve gün içinde yorgun göründüğü ve yine bu grupta belirgin artmış davranış bozukluğu ve öğrenme güçlüğü olduğu belirlendi.
Sonuç: Bu çalışma obez çocuklarda azalmış uyku kalitesi ve işeme bozukluğunun sağlıklı gruba göre yüksek prevalansını gösteren ilk çalışmadır. Obezitenin bir çok sistemi olumsuz etkilemesine bağlı olarak ortaya çıkan patolojiler çocukluk çağında da hastalığın bir sendrom olarak değerlendirilmesinin gerekliliğini ortaya koymaktadır. Bu hastalarda multidisipliner yaklaşım tedavi başarısını artıracaktır. 

References

  • Kohut T, Robbins J, Panganiban J. Update on childhood/adolescent obesity and its sequela. Curr Opin Pediatr. 2019;31(5):645-653. doi:10.1097/MOP.0000000000000786
  • Kyle TK, Dhurandhar EJ, Allison DB. Regarding obesity as a disease: evolving policies and their implications. Endocrinol Metab Clin North Am. 2016;45(3):511-20. doi:10.1016/j.ecl.2016.04.004
  • Gkalonaki I, Patoulias I. Dysfunctional elimination syndrome: a short review of the literature. Folia Med Cracov. 2021;61(2):79-90. doi: 10.24425/fmc.2021.137225
  • Fuselier A, Hanberry J, Margaret Lovin J, Gomelsky A. Obesity and stress urinary ıncontinence: ımpact on pathophysiology and treatment. Curr Urol Rep. 2018;22;19(1):10. doi:10.1007/s11934-018-0762-7
  • Kim JK, Lee YG, Han K, Han JH. Obesity, metabolic health, and urological disorders in adults: a nationwide population-based study. Sci Rep. 2021;22;11(1):8687. doi:10.1038/s41598-021-88165-z
  • Bonnet MH, Arand DL. Clinical effects of sleep fragmentation versus sleep deprivation. Sleep Med Rev. 2003;7(4):297-310. doi:10.1053/smrv.2001.0245
  • McHill AW, Wright KP Jr. Role of sleep and circadian disruption on energy expenditure and in metabolic predisposition to human obesity and metabolic disease. Obes Rev. 2017;18;(1):15-24. doi:10.1111/obr.12503
  • Tucker KM, Ingram M, Doubleday K, Piper R, Carvajal SC. La Vida Buena (The Good Life) evaluation: a quasi experimental intervention of a community health worker-led family-based childhood obesity program for Latino children 5-8 years of age on the US-Mexico border. BMC Public Health. 2019;14;19(1):759. doi:10.1186/s12889-019-7081-x
  • Savoie MB, Lee KA, Subak LL, ve ark. Beyond the bladder: poor sleep in women with overactive bladder syndrome. Am J Obstet Gynecol. 2020;222(6):600.e1-600.e13. doi:10.1016/j.ajog.2019.12.005
  • Winkelman WD, Warsi A, Huang AJ, ve ark. Sleep quality and daytime sleepiness among women with urgency predominant urinary ıncontinence. Female Pelvic Med Reconstr Surg. 2018;24(2):76-81. doi:10.1097/SPV.0000000000000547
  • Anderson LN, Carsley S, Lebovic G, ve ark. Misclassification of child body mass index from cut-points defined by rounded percentiles instead of Z-scores. BMC Res Notes. 2017;28;10(1):639. doi:10.1186/s13104-017-2983-0
  • Abrams P, Cardozo L, Fall M, ve ark. The standardisation of terminology of lower urinary tract function. Report from the standardisation subcommittee of the International Continence Society. Neurourol Urodyn. 2002;21(2):167-78. doi: 10.1002/nau.10052
  • Thomas-Eapen N. Childhood Obesity. Prim Care. 2021;48(3):505-515. doi:10.1016/j.pop.2021.04.002
  • Gondim R, Gorjão J, Nacif A, Franco I, Barroso U Jr. Evaluation of autonomic function in children and adolescents with overactive bladder. Int Braz J Urol. 2021;47(6):1178-1188. doi:10.1590/S1677-5538.IBJU.2021.0177
  • Caldwell PH. Tips for managing treatment-resistant enuresis. J Paediatr Child Health. 2018;54(10):1060-1064. doi:10.1111/jpc.14158
  • Karmali S, Ng V, Battram D, ve ark. Coaching and/or education intervention for parents with overweight/obesity and their children: study protocol of a single-centre randomized controlled trial. BMC Public Health. 2019;28;19(1):345.doi:10.1186/s12889-019-6640-5.
  • Su MS, Xu L, Pan WF, Li CC. Current perspectives on the correlation of nocturnal enuresis with obstructive sleep apnea in children. World J Pediatr. 2019;15(2):109-116. doi:10.1007/s12519-018-0199-6
  • Fuselier A, Hanberry J, Margaret Lovin J, Gomelsky A. Obesity and stress urinary ıncontinence: ımpact on pathophysiology and treatment. Curr Urol Rep. 2018;22;19(1):10. doi:10.1007/s11934-018-0762-7
  • Smith L, Toussaint L, Micoli A, Lynch B. Obesity, putative biological mediators, and cognitive function in a national sample of children and adolescents. Prev Med. 2021;150:106659. doi:10.1016/j.ypmed.2021.106659
  • Fernández-Andújar M, Morales-García E, García-Casares N. obesity and gray matter volume assessed by neuroimaging: a systematic review. Brain Sci. 2021;28;11(8):999. doi:10.3390/brainsci11080999
  • Spiegel K, Leproult R, Colecchia EF, ve ark. Adaptation of the 24-h growth hormone profile to a state of sleep debt. Am J Physiol Regul Integr Comp Physiol. 2000;279(3):R874-83. doi:10.1152/ajpregu.2000.279.3.R874
  • Ma Y, Liang L, Zheng F, Shi L, Zhong B, Xie W. Association between sleep duration and cognitive decline. JAMA Netw Open. 2020;1;3(9):e2013573. doi:10.1001/jamanetworkopen.2020.13573
There are 22 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Research article
Authors

Nadide Melike Sav 0000-0003-1520-6426

Mehmet Ali Sungur 0000-0001-5380-0819

Önder Kiliçaslan 0000-0002-9311-006X

Seda Erişen Karaca 0000-0002-8899-8412

Early Pub Date August 29, 2022
Publication Date September 1, 2022
Submission Date February 18, 2022
Acceptance Date August 18, 2022
Published in Issue Year 2022 Volume: 7 Issue: 3

Cite

AMA Sav NM, Sungur MA, Kiliçaslan Ö, Erişen Karaca S. Obez Çocuklarda Uyku Kalitesi ve İşeme Fonksiyonunun Değerlendirilmesi. OTJHS. September 2022;7(3):446-452. doi:10.26453/otjhs.1075795

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