Akut Generalize Ekzantematöz Püstülozis

Year 2013, Volume: 11 Issue: 2, 77 - 80, 01.09.2013

Hikmet Tekin Nacaroğlu Demet Can

https://doi.org/10.4274/Jcp.11.77486

Abstract

Akut generalize ekzantematöz püstülozis AGEP , klinik olarak ani başlayan, ateşle birlikte tüm vücutta yaygın püstüler döküntü ile seyreden nadir bir dermatozdur. Vakaların %90’nında ilaç kullanım öyküsü mevcut olmakla birlikte etyopatogenezde nadiren viral ve bakteriyel enfeksiyonlar ile civaya karşı aşırı duyarlılık reaksiyonları da suçlanmaktadır. Klinik olarak eritemli zemin üzerinde, foliküler yerleşimli olmayan, çok sayıda steril püstülle karekterizedir. Hastalığın spesifik bir tedavisi yoktur, altta yatan nedenin ortadan kaldırılması ile spontan iyileşme gözlenir. Bu makalede AGEP’in etiyolojik, klinik ve histopatolojik özellikleri gözden geçirilmiştir

Keywords

Akut generalize ekzantematöz püstüloz, ilaç hipersensitivitesi, çocukluk çağı

Acute Generalized Exanthematous Pustulosis

Abstract

Acute generalized exanthematous pustulosis AGEP is a rare cutaneous rash characterized by the abrupt onset of a widespread generalized pustular rash often accompanied by fever. In the etiopathogenesis, there is a history of drug use in 90% of the cases, and occasionally hypersensitivity reactions to mercury or viral and bacterial infections are accused. Nonfollicular eruptions on a erythematous surface spreading on a large scale are clinical features. There is no specific treatment when underlying cause cured spontaneous healing occures. AGEP’s etiology clinical and histopathologic characteristics are reviewed here

Keywords

cute generalized exanthematous pustulosis, drug hypersensitivity, childhood

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