Hemofagositik Lenfohistiyositozis

Yıl 2004, Cilt: 2 Sayı: 4, 113 - 116, 01.12.2004

Özcan Bör

Öz

Hemofagositik lenfohistiyositozis HLH nadir görülen fatal seyirli bir fenomendir. Hemofagositozla karakterize malign olmayan immün regülasyon bozukluğudur. T lenfositler ve makrofajların kontrol edilemeyen aktivasyonu ve inflamatuar sitokinlerin İnterferon gama, interlökin-1, interlökin-6, tümör nekrozis faktör gibi aşırı üretimi vardır.

Kaynakça

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