Immobilization of Propolis Extract on PET Fabric for Biomedical Applications

Year 2022, Volume: 25 Issue: 3, 1299 - 1307, 01.10.2022

Ömer Yunus Gümüş , Ismahane Yssaad

https://doi.org/10.2339/politeknik.1059724

Cited By: 3

Abstract

Propolis has biological activity due to its wide variety of phenolic compound content. Propolis usage in many areas such as cosmetics, food, medicine, and biomedicals is becoming widespread day by day due to its antibacterial, antifungal, antiviral properties. In this study, phenolics extracted from propolis were covalently bonded and immobilized on the surface of polyethylene terephthalate (PET) fabric with the aim of developing a technical textile for biomedical applications. To do so, PET fabric was aminated, and then the phenolics were immobilized using polyethylene glycol diglycidyl ether (PEGDGE) as the crosslinking agent. Formation of amine groups in PET structure and immobilization of the phenolics were proved by ATR-FTIR spectrums. Water contact angle of PET being 121° decreased to 110° and 97° after the amination and the immobilization, respectively. Optical microscope images were taken to monitor morphological changes after the processes. DSC results revealed a new endothermic peak at around 40 °C for modified PET. Tensile tests showed that tensile strength of the fabric weakens upon modification, while a healing effect occurs during immobilization. Antibacterial tests revealed that propolis extract immobilized fabric has an antibacterial activity against gram negative (E. coli) bacteria.

Keywords

Propolis, immobilization, technical textile, antibacterial activity, polyethylene terephthalate

Biyomedikal Uygulamalar için Propolis Ekstresinin PET Kumaş Üzerine İmmobilizasyonu

Abstract

Propolis, çok çeşitli fenolik bileşik içeriği nedeniyle biyolojik aktiviteye sahiptir. Propolisin antibakteriyel, antifungal, antiviral özellikleri nedeniyle kozmetik, gıda, ilaç, biyomedikal gibi birçok alanda kullanımı her geçen gün yaygınlaşmaktadır. Bu çalışmada, biyomedikal uygulamalar için teknik bir tekstil geliştirmek amacıyla propolisten ekstrakte edilen fenolikler polietilen tereftalat (PET) kumaş yüzeyine kovalent olarak bağlanmış ve immobilize edilmiştir. Bunu yapmak için, PET kumaş aminlendi ve daha sonra fenolikler, polietilen glikol diglisidil eter (PEGDGE) çapraz bağlama ajanı kullanılarak kumaş üzerin immobilize edildi. PET yapısında amin gruplarının oluşumu ve fenoliklerin immobilizasyonu ATR-FTIR spektrumları ile kanıtlanmıştır. 121° olan PET'in su temas açısı aminasyon ve immobilizasyon sonrasında sırasıyla 110° ve 97°'ye düşmüştür. İşlemlerden sonraki morfolojik değişiklikleri izlemek için optik mikroskop görüntüleri alındı. DSC sonuçları, modifiye edilmiş PET için yaklaşık 40 °C'de yeni bir endotermik pik ortaya çıkardı. Çekme testleri, kumaşın mukavemetinin modifikasyon üzerine zayıfladığını, immobilizasyon sırasında ise onarıcı bir etki meydana geldiğini göstermiştir. Antibakteriyel testler, propolis ekstresi immobilize edilmiş kumaşın gram negatif (E. coli) bakterilere karşı antibakteriyel aktiviteye sahip olduğunu ortaya koymuştur.

Keywords

Propolis, immobilizasyon, Teknik tekstil, antibakteriyel aktivite, polietilen tereftalat

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