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Medikal Ozon Tedavisi ve COVID-19

Year 2020, Volume: 7 Issue: 4, 304 - 310, 01.12.2020

Mustafa İkizek Yasin Uzuntarla

Abstract

Geleneksel ve tamamlayıcı tıp kapsamında kullanılan ozon tedavisi, medikal kullanımının yanı sıra sağlığın korunması, geliştirilmesi, spor performansının artırılması ve estetik amacıyla da kullanılan bir yöntemdir. Bu çalışmada ozonun medikal tedavideki tarihsel gelişimi, kullanım yöntemleri, etkileri ve COVID-19 hastalığındaki kullanımının incelenmesi amaçlanmıştır. Araştırma kapsamında literatür incelemesi yapılarak ulusal ve uluslar arası çalışmalar incelenmiştir. Yapılan analiz sonucunda ozon tedavisinin sıklıkla romatizmal, inflamatuvar ve diş hastalıklarının tedavisinde kullanıldığı, en çok majör otohemoterapi yönteminin tercih edildiği görülmektedir. Ozon tedavisinin birçok hastalıkta ve COVID-19’da olumlu etkisinin olduğunu gösteren çalışmaların sayısında artış görülse de, klinik çalışmaların yetersiz olduğu ve halen bazı önyargıların da bulunduğunu söyleyebiliriz.

Keywords

ozon ozon terapi medikal ozon COVID-19

References

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  • 2) Braidy N, Izadi M, Sureda A, Jonaidi-Jafari N, Banki A, Nabavi SF, Nabavi SM. Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain. J Cell Physiol. 2018;233(4):2705-2714. doi:10.1002/jcp.26044
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  • 4) Nogales CG, Ferrari PA, Kantorovich EO, Lage-Marques JL. Ozone therapy in medicine and dentistry. J Contemp Dent Pract. 2008;9(4):75-84.
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  • 6) Özler M, Öter Ş, Korkmaz A. Ozon gazının tıbbi amaçlı kullanılması. TAF Prev Med Bull. 2009;8(1) :59-64.
  • 7) Kogelschatz U. Dielectric-barrier discharges: Their history, discharge physics, and ındustrial applications. Plasma Chemistry and Plasma Processing. 2003;23(1):1-46.
  • 8) Sagai M, Bocci V. Mechanisms of action involved in ozone therapy: Is healing induced via a mild oxidative stress? Med Gas Res. 2011;1:29.
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Year 2020, Volume: 7 Issue: 4, 304 - 310, 01.12.2020

Mustafa İkizek Yasin Uzuntarla

Abstract

References

  • 1) Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science. 2002;298(5601): 2195-2199.
  • 2) Braidy N, Izadi M, Sureda A, Jonaidi-Jafari N, Banki A, Nabavi SF, Nabavi SM. Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain. J Cell Physiol. 2018;233(4):2705-2714. doi:10.1002/jcp.26044
  • 3) Rubin MB. The history of ozone. The Schönbein period, 1839-1868. Bull Hist Chem. 2001;26:40-56.
  • 4) Nogales CG, Ferrari PA, Kantorovich EO, Lage-Marques JL. Ozone therapy in medicine and dentistry. J Contemp Dent Pract. 2008;9(4):75-84.
  • 5) Bocci V. Ozone as Janus: this controversial gas can be either toxic or medically useful. Mediators Inflamm. 2004; 13(1): 3-11.
  • 6) Özler M, Öter Ş, Korkmaz A. Ozon gazının tıbbi amaçlı kullanılması. TAF Prev Med Bull. 2009;8(1) :59-64.
  • 7) Kogelschatz U. Dielectric-barrier discharges: Their history, discharge physics, and ındustrial applications. Plasma Chemistry and Plasma Processing. 2003;23(1):1-46.
  • 8) Sagai M, Bocci V. Mechanisms of action involved in ozone therapy: Is healing induced via a mild oxidative stress? Med Gas Res. 2011;1:29.
  • 9) Yıldız S, Duruhan S, Biçer B, Çelik N, Çatal T. Ozon terapi: Genel bilgiler. Integr Tıp Derg. 2014;2(2):19-26.
  • 10) Babacan A. Ozon, ozonterapi ve klinik kullanımı. Turkiye Klinikleri J Med Sci. 2008;28(Suppl):245-247.
  • 11) Zanardi I,Borrelli E,Valacchi G, Travagli V, Bocci V. Ozone: a multifaceted molecule with Unexpected therapeutic activity. Curr Med Chem. 2016;23(4):304–314.
  • 12) Altınbilek T, Kaya E, Uyar M, Tuncay MS, Çiftçi ÖT, Yılmaz G, Yıldız S. Lomber disk hernisi tedavisinde ozon terapi uygulamaları. Integr Tıp Derg. 2014;2(2):38-43.
  • 13) Muto M, Andreula C, Leonardi M. Treatment of herniated lumbar disc by intradiscal and intraforaminal oxygen-ozone (O2-O3) injection. J Neuroradiol. 2004;31(3):183-189.
  • 14) Zhang Y, Ma Y, Jiang J, Ding T, Wang J. Treatment of the lumbar disc herniation with intradiscal and intraforaminal injection of oxygen-ozone. J Back Musculoskelet Rehabil. 2013;26(3):317-322.
  • 15) Wu X,Liu X,Huang H,Li ZS, Xiong T, Xiang W, et al. Effects of major ozonated autoheamotherapy on functional recovery, ischemic brain tissue apoptosis and oxygen free radical damage in the rat model of cerebral ischemia. J Cell Biochem. 2019;12(4):6772-6780.
  • 16) Wu XN, Zhang T,Wang J,Liu X, Li Z, Xiang W, et al.Magnetic resonance diffusion tensor imaging following major ozonated autohemotherapy for treatment of acute cerebral infarction. Neural Regen Res. 2016;11(7):1115–1121.
  • 17) Hao K, Tang S, Xie H, Li X, He X. Application of ozone therapy in interventional medicine. Journal of Interventional Medicine. 2019;2:8–11.
  • 18) Kurt H, Keşkek ŞÖ, Çil T, Canataroğlu A. Meme kanserli hastalarda tamamlayıcı/ alternatif tedavi kullanımı. Türk Onkoloji Dergisi. 2013;28(1):10-15.
  • 19) Kızıltan HŞ, Bayir AG, Yucesan G, Eris AH, İdin K, Karatoprak C, et al. Medical ozone and radiotherapy in a peritoneal, Erlich-ascites, tumor-cell model. Altern Ther Health Med. 2015;21(2):24-29.
  • 20) Ernst E. A primer of complementary and alternative medicine commonly used by cancer patients. The Medical Journal of Australia. 2001;174(2):88-92.
  • 21) Neogi T. Eklem ağrısı epidemiyolojisi. The International Association for the Study of Pain, 2016. (Erişim adresi: https://s3.amazonaws.com/rdcms-iasp/files/production/public/AM/Images/MemberPhotos/2016YearOfPainFactSheets/FactSheets/Turkish/11_Eklem_Agrisi_Epidemiyolojisi.pdf, Erişim tarihi: 10.08.2020).
  • 22) Kozanoğlu ME, Göncü K. Dejeneratif eklem hastalığı rehabilitasyonu. Turkish Journal of Geriatrics. 1999;2(2):71-75.
  • 23) Alan H, Vardı N, Özgür C, Acar AH, Yolcu Ü, Doğan DO. Comparison of the effects of low-level laser therapy and ozone therapy on bone healing. J Craniofac Surg. 2015;26:e396-400.
  • 24) Riva Sanseverino E. Knee-joint disorders treated by oxygen-ozone therapy. Europa Medicophysica. 1989;25:163-70.
  • 25) Vaillant JD, Fraga A, Díaz MT, Mallok A, Viebahn-Hänsler R, Fahmy Z, et al. Ozone oxidative postconditioning ameliorates joint damage and decreases pro-inflammatory cytokine levels and oxidative stress in PG/PS-induced arthritis in rats. Eur J Pharmacol. 2013;714:318-324.
  • 26) Taşbilek Yoncalık M. Ozon terapinin sporcularda etkisi. Gazi Beden Eğitimi ve Spor Bilimleri Dergisi. 2017;22(1-4): 23-30.
  • 27) Pressman S. Ozone benefits for athletes. 2012. (Erişim adresi:http://www.o3center.org/ConditionsCenter/MusculoSkeletalSystems/Ozonebenefitsforathletes.html, Erişim tarihi:10.08.2020).
  • 28) Kesikburun S, Yaşar M. Ozon tedavisi. TOTBİD Dergisi. 2017; 16:196–202.
  • 29) Hidalgo-Tallón J, Menéndez-Cepero S, Vilchez JS, Rodríguez-López CM, Calandre EP. Ozone therapy as add-on treatment in fibromyalgia management by rectal insufflation: an open-label pilot study. J Altern Complement Med. 2013;19:238-242.
  • 30) Moretti M. Effectiveness of hyaluronic acid and O2-O3 injections in lateral ankle sprains without tear of anterior talofibular ligament. Int J Ozone Therapy. 2012;11:98-100.
  • 31) Uysal B, Seven MM, Memiş A, Yıldız Y. Ozon tedavisinin spor hekimliğindeki potansiyel endikasyonları. Spor Hekimliği Dergisi. 2015;50:77-88.
  • 32) Korkmaz H, Küçükkolbaşı H. Diş hekimliğinde ozon uygulamaları. Atatürk Üniv Diş Hek Fak Derg. 2013;7:125-134.
  • 33) Beck EG, Wasser G, Viebahn-Hänsler R. The current status of ozone therapy empirical developmentsand basic research. Forsch Komplementärmed. 1989;5:61-75.
  • 34) Bocci VA. Scientific and medical aspects of ozone therapy. State of the art. Arch Med Res. 2006;37(4):425-435.
  • 35) Korkut Y, Ayada C, Toru Ü. Ozon Tedavisi ve servikal - lomber disk hernileri üzerine etkisi. Ankara Med J. 2015;15(3):161-168.
  • 36) Viebahn-Hänsler R, Lee A. The Use of Ozone in Medicine. Medicina Biologica, 4 ed., 2002.
  • 37) Dıraçoğlu D. Kas iskelet hastalıklarında ozon-oksijen tedavileri. Turk J Phys Med Rehab. 2016;62(2):183-191.
  • 38) Gracer RI, Bocci V. Can the combination of localized ‘‘proliferative therapy’’ with ‘‘minor ozonated autohemotherapy’’ restore natural healing process? Med Hypotheses. 2005;65(4):729-752.
  • 39) Babucçu O. Ozon terapi: Mit ve gerçek. Turk Plast Surg. 2011;19 (3): 105-112.
  • 40) Viebahn-Hansler R, Olga Sonia León F, Ziad F. The low-dose ozone concept-guidelines and treatment strategies. Ozone: Science & Engineering: The Journal of the International Ozone Association Ozone in Medicine. 2012; 34(6):408-424.
  • 41) Bocci V. Ozone a new medical drug. Springer Netherlands, 2005.
  • 42) Bocci VA. Tropospheric ozone toxicity vs. usefulness of ozone therapy. Arch Med. Res. 2007;38(2):265-267.
  • 43) Bocci V. Biological and clinical effects of ozone: Has ozone therapy a future in medicine? Br J Biomed Sci. 1999;56:270–279.
  • 44) Why consider ozone therapy/oxygen Spa as alternative treatment dallas fort worth?, 2010. (http://www.holisticbodyworker.com/ozone_therapy_documentation.html, Erişim tarihi:10.10.2020).
  • 45) Gérard V, Sunnen MD. SARS and ozone therapy: Theoretical considerations.2003. (http:// www. triroc. Com / sunnen / topics / sars. html, Erişim tarihi:01.10.2020).
  • 46) Bocci V, Larini A, Micheli V. Restoration of normoxia by ozone therapy may control neoplastic growth: a review and a working hypothesis. J Altern Complement Med. 2005;11:257-265.
  • 47) Inal M, Dokumacioglu A, Ozcelik E, Ucar O. The effects of ozone therapy and coenzyme Q10 combination on oxidative stress markers in healthy subjects. Ir J Med. Sci 2011;180:703-707.
  • 48) Türkiye Cumhuriyeti Sağlık Bakanlığı. Geleneksel ve Tamamlayıcı Tıp Uygulamaları Yönetmeliği, 2014. (Erişim adresi: https://www.resmigazete.gov.tr/eskiler/2014/10/20141027-3.htm, Erişim tarihi: 07.08.2020).
  • 49) Koca F. Açılış konuşması. 2. Uluslararası Geleneksel ve Tamamlayıcı Tıp Kongresi Özet Kitabı. 24-27 Nisan 2019, İstanbul. (https://getat2020.saglik.gov.tr/static/GETAT2019-%C3%96zetKitab%C4%B1.pdf, Erişim tarihi: 01.08.2020).
  • 50) Abdelhafiz AS, Mohammed Z, Ibrahim ME, Ziady HH, Alorab M, Ayyad M, et al. Knowledge, perceptions, and attitude of Egyptians towards the novel coronavirus disease (COVID-19). Journal of Community Health. 2020. https ://doi.org/10.1007/s1090 0-020-00827 -7.
  • 51) Zhong, BL, Luo W, Li HM, Zhang, QQ, Liu XG, Li WT. Knowledge, attitudes, and practices towards COVID-19 among Chinese residents during the rapid rise period of the COVID-19 outbreak: A quick online cross-sectional survey. International Journal of Biological Science. 2020;16(10):1745–1752. https://doi.org/10.7150/ijbs.45221.
  • 52) Roy D, Tripathy S, Kar SK, Sharma N, Verma SK, Kaushal V. Study of knowledge, attitude, anxiety and perceived mental healthcare need in Indian population during COVID-19 pandemic. Asian Journal of Psychology. 2020;51:102083. https ://doi.org/10.1016/j.ajp.2020.10208 3.
  • 53) World Health Organization. Coronavirus disease (COVID-19) dashboard. 2020. (https://covid19.who.int/table, Erişim tarihi:10 Eylül 2020).
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There are 65 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Review Article
Authors

Mustafa İkizek This is me 0000-0002-2553-8099

Yasin Uzuntarla 0000-0002-5021-3763

Publication Date December 1, 2020
Acceptance Date November 19, 2020
Published in Issue Year 2020 Volume: 7 Issue: 4

Cite

APA İkizek, M., & Uzuntarla, Y. (2020). Medikal Ozon Tedavisi ve COVID-19. Sağlık Akademisyenleri Dergisi, 7(4), 304-310.
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