Bazı Yeni İsatin Türevlerinin Sentezi ve Yapılarının Aydınlatılması

Abstract

Heterosiklik halka sistemlerinde önemli bir rolü olan indol, önemli biyolojik etkiler göstermektedir. Isatin (1H-indol-2,3-dion), biyolojik özellikleri nedeniyle çok sayıda sentezde bir reaktif olarak kullanılmıştır. Ayrıca, isatin, indol ve kinolin türevlerinin eldesinde ve reaksiyonlarında kullanılan, bir heterosiklik halka sistemidir.  Bu çalışmada, iki yeni Schiff bazı bileşikleri, 2-aminoantrasen ile isatin/5-nitro-isatinin reaksiyonuyla sentezlendi. Sentezlenen bileşiklerin yapısı, IR, ¹H-NMR, ¹³C-NMR spektrumları ve Kütle analizi kullanılarak spektroskopik yöntemlerle aydınlatıldı.

Keywords

• İsatin,İndol,Schiff bazı,Heterosiklik kimya,Sentez

Synthesis of Some New Isatin Derivatives and Identification of Their Structures

Abstract

Indole, which has an important role in heterocyclic ring systems, exhibits significant biological effects. Isatin (1H-indole-2,3-dione) has been used as a reagent in a large number of synthesis due to its biological properties. In addition, it is a heterocyclic ring system used for obtaining and other reactions of indole and quinoline derivatives. In this study, two new Schiff base compounds were synthesized by the reaction of 2-aminoantracene with an isatin/5-nitro-isatin. The structure of the synthesized compounds, were elucidated by spectroscopic methods using IR, ¹H-NMR, ¹³C-NMR spectra and Mass analysis.

Keywords

• Indole,Isatin,Schiff base,heterocyclic chemistry,Synthesis

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