Süleyman Demirel Üniversitesi Tıp Fakültesi Öğrencilerinin COVID-19 Aşı Tereddütünün Değerlendirilmesi

Abstract

Amaç: Çalışmamızda XXX Tıp Fakültesi (XXXTF) öğrencilerinin COVID-19 aşılarına karşı tereddütlerini ve aşılanmaya yönelik düşüncelerini değerlendirmeyi amaçladık. Materyal ve Metot: Kesitsel tipte olan bu çalışmanın örneklemini, XXXTF’nde dönem I, II, III’te öğrenim gören gönüllü 197 öğrenci oluşturmuştur. Google Forms’ta hazırlanan anket formu linki öğrencilere; 2022-2023 eğitim döneminde, Eylül-Nisan ayları arasında, WhatsApp öğrenci gruplarına gönderilerek ulaştırılmıştır. Uyguladığımız anket, Bağışıklama Uzmanları Stratejik Danışma Grubu (SAGE)’nun oluşturduğu anket formu soruları (topluluk düzeyinde aşı tereddütünü değerlendirmede dikkate alınması gereken sorular ve aşı tereddütü 5'li Likert ölçeği soruları) temel alınarak hazırlanmıştır. Anket yapılmadan önce, etik kurul onayı alınmıştır. Bulgular: %65,50’sini kadınların oluşturduğu çalışma grubunun yaş ortalaması 20,08±2,03’tür. Katılımcıların %31,00’i dönem I’de, %47,70’i dönem II’de ve %21,30’u ise dönem III’te aktif öğrenim görmektedir. Katılımcıların %40,60’ı aşı konusunda isteksiz davranıp/tereddüt etmiştir. Katılımcıların, aşıdan tereddüt etme/reddetme sebeplerinden ilkinin yan etkilerden duyulan endişe olduğu saptanmıştır (%65,00). Katılımcıların Likert ölçeğinde; aşıdan tereddüt etme/reddetme sebepleri arasında, ciddi yan etkiler oluşturabileceği konusunda duyulan endişenin, 3,15±1,150 ortalamasında olduğu bulunmuştur. Katılımcılar, aşı kararlarını etkileyen kişilerin, %83,80 oranıyla sağlık çalışanları olduğunu belirtmiştir. Aşı konusunda isteksiz davranma veya tereddüt etme durumu (p=0,028), aşıların gerekli ve etkili olduğunu düşünüp ciddi hastalıklardan koruyabileceğine olan inanç (p=0,001), sağlık çalışanlarının aşı kararını etkileyen kişiler arasında olduğunu düşünme durumları ile; Likert ölçek puanları arasında anlamlılık tespit edildi (p=0,001). Sonuç: Dönem I, II, III öğrencilerinde COVID-19 aşılarına karşı genel tutum olumlu olmakla birlikte aşı yaptırma konusunda tereddütü olanların oranının da az olmadığı gözlemlenmiştir.

Keywords

• COVID-19
• aşı kabulü
• aşı tereddütü
• tıp fakültesi öğrencileri

Evaluation of COVID-19 Vaccine Hesitancy among Süleyman Demirel University Faculty of Medicine Students

Abstract

Objectives: In our study, we aimed to evaluate the hesitations of XXX Faculty of Medicine (XXXTF) students towards COVID-19 vaccines and their thoughts about vaccination. Material and Method: The sample of this cross-sectional study consisted of 197 volunteer students studying at XXXTF in terms I, II and III. The survey form link prepared in Google Forms was sent to WhatsApp student groups between September and April in the 2022-2023 academic year. The survey we implemented was prepared based on the survey form questions created by the Strategic Advisory Group of Immunization Experts (SAGE) (questions that should be taken into account in assessing vaccine hesitancy at the community level and vaccine hesitancy 5-point Likert scale questions). Before conducting the survey, ethics committee approval was obtained. Results: The average age of the study group, 65.50% of which is women, is 20.08±2.03. 31.00% of the participants are actively learning in term I, 47.70% in Term II and 21.30% in Term III. 40.60% of the participants were reluctant/hesitant about vaccination. It was determined that the first reason why participants hesitated/rejected the vaccine was concern about side effects (65.00%). On the Likert scale of the participants; Among the reasons for hesitating/rejecting the vaccine, the concern that it may cause serious side effects was found to have an average of 3.15±1.150. Participants stated that the people who influence vaccination decisions are healthcare workers with a rate of 83.80%. Reluctance or hesitation about vaccination (p=0.028), belief that vaccines are necessary and effective and can protect against serious diseases (p=0.001), and thinking that healthcare professionals are the ones who influence the vaccine decision (p=0.001); significance was determined between Likert scale scores. Conclusion: Although the general attitude towards COVID-19 vaccines was positive among term I, II, III students, it has been observed that the proportion of those who are hesitant about getting vaccinated is not low.

Keywords

• COVID-19
• Vaccine Acceptance
• Vaccine Hesitancy
• Medical Faculty Students

References

1. 1. Xia Y, Zhong L, Tan J, Zhang Z, Lyu J, Chen Y, et al. How to understand “herd immunity” in COVID-19 pandemic. Front Cell Dev Biol. 2020;8:547314.
2. 2. Dinakaran D, Manjunatha N, Kumar CN, Suresh BM. Neuropsychiatric aspects of COVID-19 pandemic: A selective review. Asian J Psychiatr. 2020;53:102188.
3. 3. Cucinotta D, Vanelli M. WHO declares COVID-19 a pandemic. Acta Biomed. 2020;91(1):157–60.
4. 4. Lucia VC, Kelekar A, Afonso NM. COVID-19 vaccine hesitancy among medical students. J Public Health. 2021;43(3):445–9.
5. 5. Chen M, Li Y, Chen J, Wen Z, Feng F, Zou H, et al. An online survey of the attitude and willingness of Chinese adults to receive COVID-19 vaccination. Hum Vaccin Immunother. 2021;17:1–10.
6. 6. Al-Metwali BZ, Al-Jumaili AA, Al-Alag ZA, Sorofman B. Exploring the acceptance of COVID-19 vaccine among healthcare workers and general population using health belief model. J Eval Clin Pract. 2021;27:1112–22.
7. 7. Muhammed K, Rzymski P, Islam S, Makuku R, Mushtaq A, Han A, et al. COVID-19 vaccinations: The unknowns, challenges, and hopes. J Med Virol. 2021;37.
8. 8. Fiolet T, Kherabi Y, MacDonald CJ, Ghosn J, Peiffer-Smadja N. Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review. Clin Microbiol Infect. 2022;28(2):202–21.

9. 9. Kateeb E, Danadneh M, Pokorná A, Klugarová J, Abdulqader H, Klugar M, et al. Predictors of willingness to receive COVID-19 vaccine: cross-sectional study of Palestinian dental students. Vaccines. 2021;9:954.
10. 10. Wang J, Jing R, Lai X, Zhang H, Lyu Y, Knoll MD, et al. Acceptance of COVID-19 vaccination during the COVID-19 pandemic in China. Vaccines. 2020;8:482.
11. 11. Harapan H, Wagner AL, Yufika A, Winardi W, Enver S, Gan AK, et al. Acceptance of a COVID-19 vaccine in Southeast Asia: a cross-sectional study in Indonesia. Front Public Health. 2020;8:1–8.
12. 12. Sallam M. COVID-19 vaccine hesitancy worldwide: a concise systematic review of vaccine acceptance rates. Vaccines. 2021;9:160.
13. 13. Salali GD, Uysal MS. COVID-19 vaccine hesitancy is associated with beliefs on the origin of the novel coronavirus in the UK and Turkey. Psychol Med. 2020;1–3.
14. 14. MacDonald NE. Vaccine hesitancy: Definition, scope and determinants. Vaccine. 2015;33:4161–4.
15. 15. Dubé E, Gagnon D, MacDonald NE, SAGE Working Group on Vaccine Hesitancy. Strategies intended to address vaccine hesitancy: Review of published reviews. Vaccine. 2015;33:4191–203.
16. 16. Lane S, MacDonald NE, Marti M, Dumolard L. Vaccine hesitancy around the globe: Analysis of three years of WHO/UNICEF Joint Reporting Form data—2015–2017. Vaccine. 2018;36:3861–7.
17. 17. Bozkurt HB. Aşı Reddine Genel Bir Bakış ve Literatürün Gözden Geçirilmesi (An Overview of Vaccine Rejection and Review of Literature). Kafkas J Med Sci. 2018;8(1):71–6.
18. 18. WHO, SAGE Vaccine Hesitancy Working Group. What influences vaccine acceptance: A model of determinants of vaccine hesitancy. [cited 2018].
19. 19. Hausman BL, Ghebremichael M, Hayek P, Mack E. ‘Poisonous, filthy, loathsome, damnable stuff’: the rhetorical ecology of vaccination concern. Yale J Biol Med. 2014;87:403–16.7
20. 20. Terrell R, Alami A, Krewski D. Interventions for COVID-19 Vaccine Hesitancy: A Systematic Review and Narrative Synthesis. Int J Environ Res Public Health. 2023;20(12):6082.
21. 21. Barello S, et al. ‘Vaccine hesitancy’ among university students in Italy during the COVID-19 pandemic. Eur J Epidemiol. 2020;35:781–3.
22. 22. Tavolacci MP, Dechelotte P, Ladner J. COVID-19 vaccine acceptance, hesitancy, and resistancy among university students in France. Vaccines. 2021;9(6):654.
23. 23. Wallen J. Medical students to be sent to Covid frontlines as India’s hospitals face collapse. The Telegraph [Internet]. 2021 May 18 [cited 2021 May 18]. Available from: https://www.telegraph.co.uk/global-health/science-and-disease/medical-students-sent-covid-frontlines-indias-hospitals-face/.
24. 24. Saatçı E. COVID-19 Pandemic and health professionals: Keep them alive or survive? Türk Aile Hek Dergisi. 2020;24(3):153–66.
25. 25. Nguyen LH, Drew DA, Graham MS, et al. Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study. Lancet Public Health. 2020;5(9):e475–83.
26. 26. Larson HJ, Jarrett C, Schulz WS, Chaudhuri M, Zhou Y, Dubé E, et al. Measuring vaccine hesitancy: The development of a survey tool. Vaccine. 2015;33(34):4165–75.
27. 27. Pandher R, Bilszta JLC. Novel COVID-19 vaccine hesitancy and acceptance, and associated factors, amongst medical students: a scoping review. Med Educ Online. 2023;28(1).
28. 28. Britton T, Ball F, Trapman P. A mathematical model reveals the influence of population heterogeneity on herd immunity to SARS-CoV-2. Science. 2020;369(6505):846–9.
29. 29. Venkatesan K, Menon S, Haroon NN. COVID-19 vaccine hesitancy among medical students: a systematic review. J Educ Health Promot. 2022;11(1):218.
30. 30. Bolatov AK, Seisembekov TZ, Askarova AZ, et al. Barriers to COVID-19 vaccination among medical students in Kazakhstan: development, validation, and use of a new COVID-19 vaccine hesitancy scale. Hum Vaccin Immunother. 2021;17(12):4982–92.
31. 31. Kaya MO, Yakar B, Pamukcu E, et al. Acceptability of a COVID-19 vaccine and role of knowledge, attitudes and beliefs on vaccination willingness among medical students. Eur Res J. 2021;7(4):417–24.
32. 32. Habib SS, Alamri MS, Alkhedr MM, et al. Knowledge and attitudes of medical students toward COVID-19 vaccine in Saudi Arabia. Vaccines. 2022;10(4):541.
33. 33. Kanyike AM, Olum R, Kajjimu J, et al. Acceptance of the coronavirus disease-2019 vaccine among medical students in Uganda. Trop Med Health. 2021;49(1):37.
34. 34. Raja SM, Osman ME, Musa AO, et al. COVID-19 vaccine acceptance, hesitancy, and associated factors among medical students in Sudan. PLoS One. 2022;17(4):e0266670.
35. 35. Grewal M, Mushtaq A, Chopra T. “It’s worth a shot ... or is it?” Notes from the grassroots on vaccine hesitancy and bridging gaps. Infect Control Hosp Epidemiol. 2021.
36. 36. Kelekar AK, Lucia VC, Afonso NM, et al. COVID-19 vaccine acceptance and hesitancy among dental and medical students. J Am Dent Assoc. 2021;152(8):596–603.
37. 37. Peterson CJ, Lee B, Nugent K. COVID-19 Vaccination Hesitancy among Healthcare Workers—A Review. Vaccines. 2022;10(6):948.
38. 38. Verger P, Botelho-Nevers E, Garrison A, et al. Vaccine hesitancy in health-care providers in Western countries: a narrative review. Expert Rev Vaccines. 2022;21(7):909–27.
39. 39. Martin LR, Petrie KJ. Understanding the dimensions of anti-vaccination attitudes: the Vaccination Attitudes Examination (VAX) scale. Ann Behav Med. 2017;51(5):652–60.
40. 40. Paul E, Steptoe A, Fancourt D. Attitudes towards vaccines and intention to vaccinate against COVID-19: implications for public health communications. Lancet Reg Health Eur. 2021;(1):100012.
41. 41. Rosenthal S, Cummings CL. Influence of rapid COVID-19 vaccine development on vaccine hesitancy. Vaccine. 2021;39(52):7625–32.
42. 42. Loomba S, de Figueiredo A, Piatek SJ, de Graaf K, Larson HJ. Measuring the impact of COVID-19 vaccine misinformation on vaccination intent in the UK and USA. Nat Hum Behav. 2021;5(3):337–48.
43. 43. Garcia LL, Yap JFC. The role of religiosity in COVID-19 vaccine hesitancy. J Public Health (Oxf). 2021;43(3):e529–30.
44. 44. Galang JRF. Science and religion for COVID-19 vaccine promotion. J Public Health (Oxf). 2021;43(3):e513–4.
45. 45. Zhang V, Zhu P, Wagner AL. Spillover of Vaccine Hesitancy into Adult COVID-19 and Influenza: The Role of Race, Religion, and Political Affiliation in the United States. Int J Environ Res Public Health. 2023;20(4):3376.
46. 46. Ayub S, Anugwom GO, Basiru T, et al. Bridging science and spirituality: the intersection of religion and public health in the COVID-19 pandemic. Front Psychiatry. 2023;19(14):1183234.
47. 47. Zimmerman T, Shiroma K, Fleischmann KR, et al. Misinformation and COVID-19 vaccine hesitancy. Vaccine. 2023;41(1):136–44.
48. 48. Cascini F, Pantovic A, Al-Ajlouni Y, et al. Social media and attitudes towards a COVID-19 vaccination: a systematic review of the literature. eClinicalMedicine. 2022;48:101454.