Pulmoner arteriyel hipertansiyon: patogenez

Önder Öztürk; Ahmet Akkaya

doi:10.17343/sdutfd.68815

Pulmoner arteriyel hipertansiyon: patogenez

Abstract

Süleyman Demirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 2008 Aralık; 15 (4) Pulmoner arteriyel hipertansiyon: patogenez Önder Öztürk, Ahmet Akaya Özet Pulmoner arteriyel hipertansiyon (PAH), endotel ve düz kas hücre proliferasyonu, media tabakasında hipertrofi, in situ trombozis ile ilişkilidir. Buna karşın PAH patogenezi tam olarak açıklanamamıştır. Vazodilatör ve vazokonstriktörler arasındaki dengenin bozulması sonucu pulmoner damar direnci artmakta ve damar duvarında yeniden yapılanma meydana gelerek PAH oluştuÃ°u düşünülmektedir. Bu derleme ile PAH patogenezinde rol oynayan mekanizmaları ve aralarındaki ilişkiyi açıklamak istedik. Anahtar kelimeler: pulmoner arteriyel hipertansiyon, patogenez, genetik. Abstract Pulmonary arterıal hypertensıon: pathogenesıs Pulmonary arterial hypertension (PAH) is histologically characterized by endothelial and smooth muscle cell proliferation, medial hypertrophy, and thrombosis in situ. However the pathogenesis of PAH remains unclear. Elevated pulmonary vascular resistance seems to result from an imbalance between locally produced vasodilators and vasoconstrictors, in addition to vascular wall remodeling. This article reviews the mechanisms of PAH and their relationships with each other. Key words: pulmonar arterial hypertension, pathogenesis, genetic

Keywords

pulmoner arteriyel hipertansiyon, patogenez, genetik

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Details

Primary Language

English

Subjects

-

Journal Section

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Authors

Önder Öztürk

Ahmet Akkaya This is me

Publication Date

May 29, 2009

Submission Date

May 29, 2009

Acceptance Date

-

Published in Issue

Year 2008 Volume: 15 Number: 4

DOI

https://doi.org/10.17343/sdutfd.68815

IZ

https://izlik.org/JA46RA53AJ

Cite

RIS / Bibtex

APA

Öztürk, Ö., & Akkaya, A. (2009). Pulmoner arteriyel hipertansiyon: patogenez. Medical Journal of Süleyman Demirel University, 15(4), 46-53. https://doi.org/10.17343/sdutfd.68815

AMA

1.Öztürk Ö, Akkaya A. Pulmoner arteriyel hipertansiyon: patogenez. Med J SDU. 2009;15(4):46-53. doi:10.17343/sdutfd.68815

Chicago

Öztürk, Önder, and Ahmet Akkaya. 2009. “Pulmoner Arteriyel Hipertansiyon: Patogenez”. Medical Journal of Süleyman Demirel University 15 (4): 46-53. https://doi.org/10.17343/sdutfd.68815.

EndNote

Öztürk Ö, Akkaya A (May 1, 2009) Pulmoner arteriyel hipertansiyon: patogenez. Medical Journal of Süleyman Demirel University 15 4 46–53.

IEEE

[1]Ö. Öztürk and A. Akkaya, “Pulmoner arteriyel hipertansiyon: patogenez”, Med J SDU, vol. 15, no. 4, pp. 46–53, May 2009, doi: 10.17343/sdutfd.68815.

ISNAD

Öztürk, Önder - Akkaya, Ahmet. “Pulmoner Arteriyel Hipertansiyon: Patogenez”. Medical Journal of Süleyman Demirel University 15/4 (May 1, 2009): 46-53. https://doi.org/10.17343/sdutfd.68815.

JAMA

1.Öztürk Ö, Akkaya A. Pulmoner arteriyel hipertansiyon: patogenez. Med J SDU. 2009;15:46–53.

MLA

Öztürk, Önder, and Ahmet Akkaya. “Pulmoner Arteriyel Hipertansiyon: Patogenez”. Medical Journal of Süleyman Demirel University, vol. 15, no. 4, May 2009, pp. 46-53, doi:10.17343/sdutfd.68815.

Vancouver

1.Önder Öztürk, Ahmet Akkaya. Pulmoner arteriyel hipertansiyon: patogenez. Med J SDU. 2009 May 1;15(4):46-53. doi:10.17343/sdutfd.68815