Pulmoner arteriyel hipertansiyon: patogenez

Önder Öztürk; Ahmet Akkaya

doi:10.17343/sdutfd.68815

Pulmoner arteriyel hipertansiyon: patogenez

Öz

Süleyman Demirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 2008 Aralık; 15 (4) Pulmoner arteriyel hipertansiyon: patogenez Önder Öztürk, Ahmet Akaya Özet Pulmoner arteriyel hipertansiyon (PAH), endotel ve düz kas hücre proliferasyonu, media tabakasında hipertrofi, in situ trombozis ile ilişkilidir. Buna karşın PAH patogenezi tam olarak açıklanamamıştır. Vazodilatör ve vazokonstriktörler arasındaki dengenin bozulması sonucu pulmoner damar direnci artmakta ve damar duvarında yeniden yapılanma meydana gelerek PAH oluştuÃ°u düşünülmektedir. Bu derleme ile PAH patogenezinde rol oynayan mekanizmaları ve aralarındaki ilişkiyi açıklamak istedik. Anahtar kelimeler: pulmoner arteriyel hipertansiyon, patogenez, genetik. Abstract Pulmonary arterıal hypertensıon: pathogenesıs Pulmonary arterial hypertension (PAH) is histologically characterized by endothelial and smooth muscle cell proliferation, medial hypertrophy, and thrombosis in situ. However the pathogenesis of PAH remains unclear. Elevated pulmonary vascular resistance seems to result from an imbalance between locally produced vasodilators and vasoconstrictors, in addition to vascular wall remodeling. This article reviews the mechanisms of PAH and their relationships with each other. Key words: pulmonar arterial hypertension, pathogenesis, genetic

Anahtar Kelimeler

pulmoner arteriyel hipertansiyon, patogenez, genetik

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Önder Öztürk

Ahmet Akkaya Bu kişi benim

Yayımlanma Tarihi

29 Mayıs 2009

Gönderilme Tarihi

29 Mayıs 2009

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2008 Cilt: 15 Sayı: 4

DOI

https://doi.org/10.17343/sdutfd.68815

IZ

https://izlik.org/JA46RA53AJ

Kaynak Göster

RIS / Bibtex

APA

Öztürk, Ö., & Akkaya, A. (2009). Pulmoner arteriyel hipertansiyon: patogenez. Medical Journal of Süleyman Demirel University, 15(4), 46-53. https://doi.org/10.17343/sdutfd.68815

AMA

1.Öztürk Ö, Akkaya A. Pulmoner arteriyel hipertansiyon: patogenez. SDÜ Tıp Fak Derg. 2009;15(4):46-53. doi:10.17343/sdutfd.68815

Chicago

Öztürk, Önder, ve Ahmet Akkaya. 2009. “Pulmoner arteriyel hipertansiyon: patogenez”. Medical Journal of Süleyman Demirel University 15 (4): 46-53. https://doi.org/10.17343/sdutfd.68815.

EndNote

Öztürk Ö, Akkaya A (01 Mayıs 2009) Pulmoner arteriyel hipertansiyon: patogenez. Medical Journal of Süleyman Demirel University 15 4 46–53.

IEEE

[1]Ö. Öztürk ve A. Akkaya, “Pulmoner arteriyel hipertansiyon: patogenez”, SDÜ Tıp Fak Derg, c. 15, sy 4, ss. 46–53, May. 2009, doi: 10.17343/sdutfd.68815.

ISNAD

Öztürk, Önder - Akkaya, Ahmet. “Pulmoner arteriyel hipertansiyon: patogenez”. Medical Journal of Süleyman Demirel University 15/4 (01 Mayıs 2009): 46-53. https://doi.org/10.17343/sdutfd.68815.

JAMA

1.Öztürk Ö, Akkaya A. Pulmoner arteriyel hipertansiyon: patogenez. SDÜ Tıp Fak Derg. 2009;15:46–53.

MLA

Öztürk, Önder, ve Ahmet Akkaya. “Pulmoner arteriyel hipertansiyon: patogenez”. Medical Journal of Süleyman Demirel University, c. 15, sy 4, Mayıs 2009, ss. 46-53, doi:10.17343/sdutfd.68815.

Vancouver

1.Önder Öztürk, Ahmet Akkaya. Pulmoner arteriyel hipertansiyon: patogenez. SDÜ Tıp Fak Derg. 01 Mayıs 2009;15(4):46-53. doi:10.17343/sdutfd.68815