Akut koroner sendrom hastalarında, obstrüktif uyku apne sendromunun değerlendirilmesi

Year 2020, , 39 - 44, 01.03.2020

Serdar Kuyumcu , Fatih Öksüz

https://doi.org/10.17343/sdutfd.464307

Abstract

Amaç: Obstrüktif uyku apne sendromu (OSAS)
kardiyovasküler hastalıklar ile yakın ilişki içindedir. Basitleştirilmiş OSAS
diyagnostik metodolojilerinin değerlendirilmesi halen yenidir ve kardiyoloji
alanında derinlemesine araştırılmamıştır. Bu çalışmada, ülkemizdeki akut
koroner sendrom (AKS) hastalarında OSAS ilişkisini ve koroner arter hastalığı
ciddiyeti ilişkisini, SYNTAX skoru, Berlin Uyku Anketi (BUA) ve Epworth
Uykululuk Ölçeği (EUÖ) kullanarak değerlendirmeyi amaçladık.

Hastalar ve
Yöntemler: Akut koroner
sendrom ile başvuran ve koroner anjiyografi yapılan 160 hasta çalışmaya dahil
edildi [n=80 ST segment yükselmeli myokard infaktüsü (STEMİ) ve n=80 ST segment
yükselmesiz myokard infaktüsü (NSTEMİ)]. Hastaların SYNTAX skorları hesaplandı.
Hastalara taburculuk öncesi  (BUA) ve
(EUÖ) uygulandı. Ölçekler iki grup arasında ve hastaların SYNTAX skoru ile
kıyaslandı.

Bulgular: NSTEMİ hastalarında BUA ve EUÖ’ye göre
yüksek riskli hasta oranı STEMİ grubuna göre istatiksel olarak anlamlı
saptanmıştır (p<0.001, p=0.023). BUA ve EUÖ’de saptanan toplam puan
miktarları NSTEMİ hastalarında STEMİ grubuna göre istatiksel olarak anlamlı
saptanmıştır (p<0.001). Pearson korelasyon analizinde SYNTAX skoru ile
BUA’da saptanan toplam puan arasında ve SYNTAX skoru ile EUÖ arasında anlamlı
pozitif korelasyon saptanmıştır (r = 0.865, p <0.001 ve r = 0.761, p
<0.001)

Sonuç: Bu çalışmada, OSAS ve AKS arasındaki
ilişki değerlendirilmiştir. BUA ve EUÖ ölçeği sonuçları literatüre göre yüksek
saptanmıştır ve SYNTAX skoru ve OSAS riski arasında pozitif korelasyon
saptanmıştır.

Keywords

Obstrüktif uyku apne sendromu, akut koroner sendrom, SYNTAX skoru

Evaluation of obstructive sleep apnea syndrome in patients with acute coronary syndrome

Abstract

Background:
Obstructive sleep apnea syndrome
(OSAS) is closely associated with cardiovascular diseases. Evaluation of
simplified OSAS diagnostic methodologies is still new and has not been deeply
investigated in the field of cardiology. In this study, we aimed to evaluate
the relationship between OSAS and the severity of coronary artery disease in
our patients with acute coronary syndrome (ACS), using the SYNTAX score, the
Berlin Sleep Questionnaire (BUA) and the Epworth Sleepiness Scale (EUÖ).

Patients &
Methods:  200 patients with acute coronary syndrome who
underwent coronary angiography were enrolled in the study. SYNTAX scores of the
patients were calculated. Patients were administered BUA and EUÖ before discharge.
The scales were compared between the two groups and with SYNTAX scores of
patients.

Results: In NSTEMI patients, the rate of high-risk patients in the
BUA and ACL was statistically significant compared to the STEMI group (p<0.001,
p=0.023). The total score of the BUA and the
total score in the EUÖ was statistically significant in NSTEMI patients
compared to the STEMI group (p<0.001).
Pearson correlation analysis revealed a significant positive correlation
between the SYNTAX score and the total score in the BUA and between the SYNTAX
score and the EUÖ (r = 0.865, p <0.001 ve r = 0.761, p <0.001)

Conclusions: In this study, the relationship between OSAS and ACS was
evaluated. The results of the BUA and EUÖ scale were higher than those of other
countries and a positive correlation was found between SYNTAX score and OSAS
risk.

Keywords

Obstructive sleep apnea syndrome, acute coronary syndrome, SYNTAX score

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