Akut koroner sendrom hastalarında, obstrüktif uyku apne sendromunun değerlendirilmesi

Abstract

Amaç: Obstrüktif uyku apne sendromu (OSAS) kardiyovasküler hastalıklar ile yakın ilişki içindedir. Basitleştirilmiş OSAS diyagnostik metodolojilerinin değerlendirilmesi halen yenidir ve kardiyoloji alanında derinlemesine araştırılmamıştır. Bu çalışmada, ülkemizdeki akut koroner sendrom (AKS) hastalarında OSAS ilişkisini ve koroner arter hastalığı ciddiyeti ilişkisini, SYNTAX skoru, Berlin Uyku Anketi (BUA) ve Epworth Uykululuk Ölçeği (EUÖ) kullanarak değerlendirmeyi amaçladık.

Hastalar ve Yöntemler: Akut koroner sendrom ile başvuran ve koroner anjiyografi yapılan 160 hasta çalışmaya dahil edildi [n=80 ST segment yükselmeli myokard infaktüsü (STEMİ) ve n=80 ST segment yükselmesiz myokard infaktüsü (NSTEMİ)]. Hastaların SYNTAX skorları hesaplandı. Hastalara taburculuk öncesi  (BUA) ve (EUÖ) uygulandı. Ölçekler iki grup arasında ve hastaların SYNTAX skoru ile kıyaslandı.

Bulgular: NSTEMİ hastalarında BUA ve EUÖ’ye göre yüksek riskli hasta oranı STEMİ grubuna göre istatiksel olarak anlamlı saptanmıştır (p<0.001, p=0.023). BUA ve EUÖ’de saptanan toplam puan miktarları NSTEMİ hastalarında STEMİ grubuna göre istatiksel olarak anlamlı saptanmıştır (p<0.001). Pearson korelasyon analizinde SYNTAX skoru ile BUA’da saptanan toplam puan arasında ve SYNTAX skoru ile EUÖ arasında anlamlı pozitif korelasyon saptanmıştır (r = 0.865, p <0.001 ve r = 0.761, p <0.001)

Sonuç: Bu çalışmada, OSAS ve AKS arasındaki ilişki değerlendirilmiştir. BUA ve EUÖ ölçeği sonuçları literatüre göre yüksek saptanmıştır ve SYNTAX skoru ve OSAS riski arasında pozitif korelasyon saptanmıştır.

Keywords

• Obstrüktif uyku apne sendromu,akut koroner sendrom,SYNTAX skoru

Evaluation of obstructive sleep apnea syndrome in patients with acute coronary syndrome

Abstract

Background: Obstructive sleep apnea syndrome (OSAS) is closely associated with cardiovascular diseases. Evaluation of simplified OSAS diagnostic methodologies is still new and has not been deeply investigated in the field of cardiology. In this study, we aimed to evaluate the relationship between OSAS and the severity of coronary artery disease in our patients with acute coronary syndrome (ACS), using the SYNTAX score, the Berlin Sleep Questionnaire (BUA) and the Epworth Sleepiness Scale (EUÖ).

Patients & Methods:  200 patients with acute coronary syndrome who underwent coronary angiography were enrolled in the study. SYNTAX scores of the patients were calculated. Patients were administered BUA and EUÖ before discharge. The scales were compared between the two groups and with SYNTAX scores of patients.

Results: In NSTEMI patients, the rate of high-risk patients in the BUA and ACL was statistically significant compared to the STEMI group (p<0.001, p=0.023). The total score of the BUA and the total score in the EUÖ was statistically significant in NSTEMI patients compared to the STEMI group (p<0.001). Pearson correlation analysis revealed a significant positive correlation between the SYNTAX score and the total score in the BUA and between the SYNTAX score and the EUÖ (r = 0.865, p <0.001 ve r = 0.761, p <0.001)

Conclusions: In this study, the relationship between OSAS and ACS was evaluated. The results of the BUA and EUÖ scale were higher than those of other countries and a positive correlation was found between SYNTAX score and OSAS risk.

Keywords

• Obstructive sleep apnea syndrome,acute coronary syndrome,SYNTAX score

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