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Pulmoner Tromboemboli Şüphesinde BT Anjiografinin Verimliliği ve Pulmoner Tromboemboli Dışı Radyolojik Bulguların Analizi

Year 2020, , 505 - 510, 25.12.2020
https://doi.org/10.17343/sdutfd.757551

Abstract

Amaç: Bu çalışmada amacımız pulmoner tromboemboli (PTE) şüphesiyle pulmoner BT anjiografi yapılan hastalarda PTE pozitiflik oranını araştırmaktı. Ayrıca BT anjiografide saptanan alternatif tanıların sıklığını ve alternatif tanıların saptanmasında akciğer grafisinin rolünü belirlemekti.
Gereç ve Yöntemler: Çalışmaya Ocak 2018- Mayıs 2018 tarihleri arasında acil servise başvuran ve PTE şüphesiyle pulmoner BT anjiografi yapılan hastalar dahil edildi. Radyolojik rapor bazında PTE negatif, PTE pozitif ve şüpheli olmak üzere hastalar üç gruba ayrıldı. PTE negatif grupta BT anjiografi incelemeleri alternatif tanılar yönünden iki radyolog tarafından gözden geçirildi. Alternatif tanılar konsolidasyon, kitle ve amfizem gibi hastaların klinik ve semptomlarını açıklayan bulgular olarak tanımlandı. Akciğer grafileri alternatif tanıların saptanabilirliği yönünden değerlendirildi. Başvuru anındaki semptomlar, klinik bulgular ve laboratuar bulguları kaydedildi.
Bulgular: Ocak 2018-Mayıs 2018 tarihleri arasında toplam 683 hastaya PTE şüphesiyle pulmoner BT anjiografi yapılmıştı. Hastaların %6,4’ünde PTE pozitifti. PTE saptanmayan hastaların %65’inde klinik bulgular ve semptomları açıklayabilecek alternatif tanılar mevcuttu. En sık alternatif tanılar konsolidasyon, atelektazi, amfizem ve bronşiektaziydi. Bu alternatif tanıların %72’si hastaların akciğer grafilerinde de izlendi. Hastaların %15’inde semptomlarla ilişkisiz insidental bulgular saptandı.
Sonuç: Çalışmamızın sonucunda PTE şüphesiyle uygulanan pulmoner BT anjiografi incelemelerinde alternatif tanıların PTE tanısından çok daha yüksek bir oranda saptandığını ve bu alternatif tanıların büyük çoğunluğunun ise BT’ye gerek kalmadan akciğer grafisi ile tespit edilebileceğini ortaya koyduk.

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References

  • 1. Stein PD, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper KV, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med. 2006;354(22):2317-27. 2.Woo JK, Chiu RY, Thakur Y, Mayo JR. Risk-benefit analysis of pulmonary CT angiography in patients with suspected pulmonary embolus. AJR Am J Roentgenol 2012;198(6):1332-9. 3. Mitchell AM, Jones AE, Tumlin JA, Kline JA. Prospective study of the incidence of contrast-induced nephropathy among patients evaluated for pulmonary embolism by contrast-enhanced computed tomography. Acad Emerg Med 2012;19(6):618-625. 4. Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VF, Sostman HD, Sos TA, et al. Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators. Am J Med 2006;119(12):1048-55. 5. Kindermann DR, McCarthy ML, Ding R, Frohna WJ, Hansen J, Maloy K, Milzman DP, et al. Emergency department variation in utilization and diagnostic yield of advanced radiography in diagnosis of pulmonary embolus. J Emerg Med. 2014 Jun;46(6):791-9. 6. Chen YA, Gray BG, Bandiera G, MacKinnon D, Deva DP. Variation in the utilization and positivity rates of CT pulmonary angiography among emergency physicians at a tertiary academic emergency department. Emerg Radiol 2015;22(3):221-9. 7.Venkatesh AK, Agha L, Abaluck J, Rothenberg C, Kabrhel C, Raja AS. Trends and variation in the utilization and diagnostic yield of chest imaging for Medicare patients with suspected pulmonary embolism in the emergency department. AJR Am J Roentgenol 2018;210(3):572–7. 8.Sharma S, Lucas CD. Increasing use of CTPA for the investigation of suspected pulmonary embolism. Postgrad Med 2017;129(2):193-7. 9. Costa AF, Basseri H, Sheikh A, Stiell I, Dennie C. The yield of CT pulmonary angiograms to exclude acute pulmonary embolism. Emerg Radiol. 2014;21(2):133-41. 10. Costantino MM, Randall G, Gosselin M, Brandt M, Spinning K, Vegas CD. CT angiography in the evaluation of acute pulmonary embolus. Am J Roentgenol 2008;191(2):471–4. 11. Shahriar Z, Stephan R, Shweta M, Arun S, Mathew T, Brijal P, et al. Could the number of CT angiograms be reduced in emergency department patients suspected of pulmonary embolism? World J Emerg Med 2012;3(3):172-6. 12. Mountain D, Keijzers G, Chu K, Joseph A, Read C, Blecher G, et al. RESPECT-ED: Rates of Pulmonary Emboli (PE) and Sub-Segmental PE with Modern Computed Tomographic Pulmonary Angiograms in Emergency Departments: A Multi-Center Observational Study Finds Significant Yield Variation, Uncorrelated with Use or Small PE Rates. PLoS ONE 2016;11(12): e0166483. 13. van Es J, Douma RA, Schreuder SM, Middeldorp S, Kamphuisen PW, Gerdes VEA, et al. Clinical impact of findings supporting an alternative diagnosis on CT pulmonary angiography in patients with suspected pulmonary embolism. Chest 2013 Dec;144(6):1893-9. 14. Anjum O, Bleeker H, Ohle R. Computed tomography for suspected pulmonary embolism results in a large number of non-significant incidental findings and follow-up investigations. Emerg Radiol 2019;26: 29-35. 15. Richardson S, Cohen S, Khan S, Zhang M, Qiu G, Oppenheim MI, et al. Higher Imaging Yield When Clinical Decision Support Is Used. J Am Coll Radiol 2020;17(4):496-503. 16. Ozakin E, Kaya FB, Acar N, Cevik AA. An analysis of patients that underwent computed tomography pulmonary angiography with the prediagnosis of pulmonary embolism in the emergency department. ScientificWorldJournal 2014;2014:470358. 17. Ferreira EV, Gazzana MB, Sarmento MB, Guazzelli PA, Hoffmeister MC, Guerra VA, et al. Alternative diagnoses based on CT angiography of the chest in patients with suspected pulmonary thromboembolism. J Bras Pneumol 2016;42(1):35-41. 18.Hall W, Truitt S, Scheunemann L. The prevalence of clinically relevant incidental findings on chest computed tomographic angiograms ordered to diagnose pulmonary embolism. Arch Intern Med 2009;169(21):1961-5.
Year 2020, , 505 - 510, 25.12.2020
https://doi.org/10.17343/sdutfd.757551

Abstract

References

  • 1. Stein PD, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper KV, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med. 2006;354(22):2317-27. 2.Woo JK, Chiu RY, Thakur Y, Mayo JR. Risk-benefit analysis of pulmonary CT angiography in patients with suspected pulmonary embolus. AJR Am J Roentgenol 2012;198(6):1332-9. 3. Mitchell AM, Jones AE, Tumlin JA, Kline JA. Prospective study of the incidence of contrast-induced nephropathy among patients evaluated for pulmonary embolism by contrast-enhanced computed tomography. Acad Emerg Med 2012;19(6):618-625. 4. Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VF, Sostman HD, Sos TA, et al. Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators. Am J Med 2006;119(12):1048-55. 5. Kindermann DR, McCarthy ML, Ding R, Frohna WJ, Hansen J, Maloy K, Milzman DP, et al. Emergency department variation in utilization and diagnostic yield of advanced radiography in diagnosis of pulmonary embolus. J Emerg Med. 2014 Jun;46(6):791-9. 6. Chen YA, Gray BG, Bandiera G, MacKinnon D, Deva DP. Variation in the utilization and positivity rates of CT pulmonary angiography among emergency physicians at a tertiary academic emergency department. Emerg Radiol 2015;22(3):221-9. 7.Venkatesh AK, Agha L, Abaluck J, Rothenberg C, Kabrhel C, Raja AS. Trends and variation in the utilization and diagnostic yield of chest imaging for Medicare patients with suspected pulmonary embolism in the emergency department. AJR Am J Roentgenol 2018;210(3):572–7. 8.Sharma S, Lucas CD. Increasing use of CTPA for the investigation of suspected pulmonary embolism. Postgrad Med 2017;129(2):193-7. 9. Costa AF, Basseri H, Sheikh A, Stiell I, Dennie C. The yield of CT pulmonary angiograms to exclude acute pulmonary embolism. Emerg Radiol. 2014;21(2):133-41. 10. Costantino MM, Randall G, Gosselin M, Brandt M, Spinning K, Vegas CD. CT angiography in the evaluation of acute pulmonary embolus. Am J Roentgenol 2008;191(2):471–4. 11. Shahriar Z, Stephan R, Shweta M, Arun S, Mathew T, Brijal P, et al. Could the number of CT angiograms be reduced in emergency department patients suspected of pulmonary embolism? World J Emerg Med 2012;3(3):172-6. 12. Mountain D, Keijzers G, Chu K, Joseph A, Read C, Blecher G, et al. RESPECT-ED: Rates of Pulmonary Emboli (PE) and Sub-Segmental PE with Modern Computed Tomographic Pulmonary Angiograms in Emergency Departments: A Multi-Center Observational Study Finds Significant Yield Variation, Uncorrelated with Use or Small PE Rates. PLoS ONE 2016;11(12): e0166483. 13. van Es J, Douma RA, Schreuder SM, Middeldorp S, Kamphuisen PW, Gerdes VEA, et al. Clinical impact of findings supporting an alternative diagnosis on CT pulmonary angiography in patients with suspected pulmonary embolism. Chest 2013 Dec;144(6):1893-9. 14. Anjum O, Bleeker H, Ohle R. Computed tomography for suspected pulmonary embolism results in a large number of non-significant incidental findings and follow-up investigations. Emerg Radiol 2019;26: 29-35. 15. Richardson S, Cohen S, Khan S, Zhang M, Qiu G, Oppenheim MI, et al. Higher Imaging Yield When Clinical Decision Support Is Used. J Am Coll Radiol 2020;17(4):496-503. 16. Ozakin E, Kaya FB, Acar N, Cevik AA. An analysis of patients that underwent computed tomography pulmonary angiography with the prediagnosis of pulmonary embolism in the emergency department. ScientificWorldJournal 2014;2014:470358. 17. Ferreira EV, Gazzana MB, Sarmento MB, Guazzelli PA, Hoffmeister MC, Guerra VA, et al. Alternative diagnoses based on CT angiography of the chest in patients with suspected pulmonary thromboembolism. J Bras Pneumol 2016;42(1):35-41. 18.Hall W, Truitt S, Scheunemann L. The prevalence of clinically relevant incidental findings on chest computed tomographic angiograms ordered to diagnose pulmonary embolism. Arch Intern Med 2009;169(21):1961-5.
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Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Research Articles
Authors

Çisel Yazgan 0000-0003-2804-7321

Hakan Ertürk 0000-0002-5730-9215

Ayşenaz Taşkın This is me 0000-0003-3288-5678

Publication Date December 25, 2020
Submission Date June 27, 2020
Acceptance Date October 21, 2020
Published in Issue Year 2020

Cite

Vancouver Yazgan Ç, Ertürk H, Taşkın A. Pulmoner Tromboemboli Şüphesinde BT Anjiografinin Verimliliği ve Pulmoner Tromboemboli Dışı Radyolojik Bulguların Analizi. Med J SDU. 2020;27(4):505-10.

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