EFFICACY OF OZONE THERAPY IN THE TREATMENT OF LUMBAR DISC HERNIATION: A SYSTEMATIC REVIEW OF 1098 PATIENTS' RESULTS

Year 2022, Volume: 29 Issue: 4, 707 - 713, 27.12.2022

Z Işık Solak Görmüş Melda Pelin Yargıç Murat Cenk Çelen

https://doi.org/10.17343/sdutfd.1120969

Abstract

Ozone therapy is widely used in the treatment of
lumbar disc herniation with intradiscal injection and
paravertebral intramuscular injection routes. This
study aims to evaluate the efficacy of ozone therapy
in the treatment of lumbar disc herniation according
to the results of randomized controlled trials. 105
articles obtained as a result of a search in Pubmed,
Google Scholar and Science Direct databases were
examined, and 9 randomized controlled studies were
included in the systematic review. In studies, it has
been observed that ozone is used in concentrations
ranging from 20 μg/ml to 60 μg/ml by intradiscal or
paravertebral route. While only ozone application can
be done in studies, it has been determined that some
studies use the effect of ozone injection in combination
with other treatment methods. It was seen that pain
was measured with a visual analog scale as the
primary output criterion of the studies. The results
of randomized controlled studies show that ozone
therapy gives more effective results in the treatment of
lumbar disc herniation compared to conventional drug
therapy, and increases the effectiveness of treatment
when added to other minimally invasive treatments. It
also leads to less hospital stay and lower treatment
costs compared to surgery.

Keywords

low back pain, ozone, intervertebral disc herniation

LOMBER DİSK HERNİSİ TEDAVİSİNDE OZON TERAPİNİN ETKİNLİĞİ: 1098 HASTANIN SONUÇLARININ SİSTEMATİK DERLEMESİ

Abstract

Ozon terapi, lomber disk hernisi tedavisinde, intradiskal
enjeksiyon ve paravertebral kas içi enjeksiyon
şeklinde yaygın olarak kullanılmaktadır. Bu sistematik
derlemenin amacı, lomber disk herniasyonu tedavisinde
ozon tedavisinin etkinliğinin randomize kontrollü
çalışma sonuçlarına göre değerlendirilmesidir.
Pubmed, Google Akademik ve Science Direct veritabanlarında
yapılan arama sonucunda elde edilen
105 makale incelenerek 9 adet randomize kontrollü
araştırma sistematik derleme kapsamına alınmıştır.
Araştırmalarda ozonun intradiskal ya da paravertebral
yolla, 20 μg/ml ile 60 μg/ml arasında değişen konsantrasyonlarda
kullanıldığı görülmüştür. Araştırmalarda
sadece ozon uygulaması yapılabildiği gibi, bazı araştırmalar
ozon enjeksiyonunun etkisini başka tedavi
yöntemleriyle kombinasyon halinde kullandığı saptanmıştır.
Araştırmalarda değerlendirme parametresi
olarak genelde ağrının görsel analog skala (GAS) ile
ölçüldüğü görülmüştür. Randomize kontrollü çalışma
sonuçları, ozon terapinin lomber disk hernisi tedavisinde
konvansiyonel ilaç tedavisine kıyasla daha etkili
olduğu ve minimal invaziv tedavilere eklendiğinde ise
tedavi etkinliğini artırdığı görülmüştür. Ayrıca cerrahiye
kıyasla daha az hastanede yatış süresine ve daha
düşük tedavi maliyetine yol açmaktadır.

Keywords

bel ağrısı, ozon, Lomber disk hernisi

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