Herediter anjioödemde kısa dönem danazol profilaksisi ile implant tedavisi: Vaka raporu

Year 2019, Volume: 6 Issue: 2, 190 - 195, 01.08.2019

Zeynep Burçin Gönen , Fatma Doğruel Canay Yılmaz Asan , Leylagül Kaynar , Mustafa Çetin

https://doi.org/10.15311/selcukdentj.384245

Abstract

Herediter anjio ödem (HAÖ), C1
esteraz inhibitör proteininin konjenital eksikliğine bağlı olarak meydana
gelen, nadir gözlenen, otozomal dominant bir hastalıktır. HAÖ atakları, spontan
veya bir travmaya bağlı olarak, ekstremitelerde, yüzde, göğüste, hava yolunda
veya karın bölgesinde şişlikler şeklinde meydana gelebilir. Dental işlemlerden
önce, profilaksi amacıyla , androjenler, taze dondurulmuş plazma, C1 esteraz
inhibitör protein konsantreleri ve antifibrinolitikler kullanılmaktadır. Bu
vaka raporunda, danazol profilaksisi ile implant tedavisi uygulanan, herediter
anjioödemli bir hasta sunulmaktadır. Preoperatif 3 gün 100 mg ve operasyon günü
200 mg danazol profilaksisi ile hastanın sol üst molar bölgesine bir adet
dental implant (Straumann Roxolid Implants) yerleştirilmiş ve post operatif 2
gün 100 mg danazol tedavisine devam edilmiştir. Hastada implant tedavisine
bağlı olarak, akut veya post operatif herhangi bir atak görülmemiştir. Sonuç
olarak, rekürrent anjio ödem hikayesi olan hastalar, dental implant cerrahisinden
önce, C1 esteraz inhibitör protein eksikliği yönünden, dikkatle
değerlendirilmelidir.

Keywords

: herediter anjio ödem, danazol

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