Zencefil-Balın Farklı Derinlikteki Başlangıç Mine Lezyonlarında Remineralizasyon Potansiyeli

Year 2025, Volume: 12 Issue: 1, 80 - 87, 21.04.2025

Esma Turkmen , Dilek Tağtekin , Zeynep Ceren Çelik , Funda Yanıkoğlu

https://doi.org/10.15311/selcukdentj.1499934

Abstract

Amaç: Bu çalışma, deneysel olarak oluşturulmuş başlangıç çürüklerinde etken maddesi zencefil ve bal olan diş macununun remineralizasyon etkinliğinin ultrason, FluoreCam yüzey mikrosertlik ölçüm metodlarıyla tespit edilmesini amaçlamıştır.

Gereç ve Yöntemler: Toplam 105 adet mine örneği 3 anagruba ayrılarak 18(D1), 36 (D2) ve 72 saat demineralizasyon solüsyonu içerisinde bekletilerek başlangıç ölçümleri ultrason, Fluorecam ve yüzey mikrosertlik, SEM ölçümleri alınmış, tüm derinlik grupları 3’er gruba ayrılarak NaF içeren diş macunu (R1N) zencefil-bal içeren diş kremi (R1Z) (Gumgumix) günde 3 defa 5 dk boyunca diş fırçası yardımı ile topikal uygulanmış ve remineralizasyon solüsyonunda bekletilerek ölçümleri alınmıştır. Sürekli verilerin karşılaştırılmasında Tek yönlü ANOVA testi kullanılmıştır.

Bulgular: Çalışmamızda da 53 mikronluk başlangıç mine lezyonlarında (D1) zencefil-bal içeren diş kremi anlamlı remineralizasyon değerleri vermiştir (p=0,033). Aynı şekilde 80 mikronluk lezyonun (D2) FluoreCam size, mikroskop ve mikrosertlik sonuçlarında da remineralizasyon bariz olarak gösterilmiştir (p=0,001, p<0,001, p=0,001). 140 mikronluk lezyonlarda (D3) FluoreCam, mikroskop, ve mikrosertlik tarafından değişim fark edilirken, ultrason da gerek demineralizasyon gerekse remineralizasyon değişimlerini fark etmiştir (p=0,035, p=0,025). Remineralizasyon ve demineralizasyon farkları kıyaslandığında, genel olarak tüm gruplarda ultrason metodu, mikrosertlik kontrol metodu ile uyumlu olarak fark gösteren tek metot olmuştur. Ayrıca genel değerlendirmede zencefil-bal içeren diş kremi en yüksek remineralizasyon değerlerini vermiştir.

Sonuçlar: Zencefil-bal içeren diş kremi uygulanması, tüm demineralizasyon derinliği gruplarında NaF uygulamasına göre daha fazla remineralizasyon etkisi göstermiştir.

Anahtar Kelimeler: Başlangıç mine lezyonu, Zencefil, remineralizasyon, ultrason, FluoreCam.

Keywords

Başlangıç mine lezyonu, Zencefil, remineralizasyon, ultrason, FluoreCam.

Supporting Institution

Marmara Üniversitesi Bilimsel Araştırma Projeleri Komisyonu Başkanlığı

Project Number

SAG-C-DUP-250416-0171

Remineralization Potential of Ginger-Honey on Initial Enamel Lesions of Different Depth

Abstract

Aim: The present study aims to determine the remineralization efficacy of toothpaste with the active ingredients of ginger and honey on in-vitro produced early dental caries lesions by using ultrasound, fluorescence, surface microhardness and light and scanning electron microscope methods.
Methods: Total of 105 enamel samplesin total were divided into three main groups which were exposed to a demineralizing solution for 18 (D1), 36 (D2), and 72 (D3) hours to take initial measurements by ultrasound, fluorescence, and surface microhardness, SEM. All main groups were divided into three subgroups each then, topically applied a toothpaste with NaF content (R1N) and a dental toothpaste with ginger-honey content (R1G) (Gumgumix) by a toothbrush three times a day for five minutes and stored in remineralizing solution, measured at the end. The one-way ANOVA test was used to compare the continuous data.
Results: Toothpaste with ginger-honey content produced significant remineralization results (p=0.033) on the 52-micron initial enamel lesions (D1) by microhardness. Similarly, the fluorescence size (p=0.001), microscope (p<0.001) and microhardness (p=0.001) results of the 80-micron lesion distinctly showed remineralization. In the 140-micron lesions (D3), the FluoreCam, microscope, and microhardness marked some changes on demineralization while the ultrasound detected the changes on both the demineralization and remineralization (p=0.035, p=0.025). When the remineralization and demineralization variations were compared, the ultrasound method, along with the microhardness, control, method, appeared to be the only method that differed in all groups in general. In addition, the dental toothpaste with ginger-honey content produced the highest remineralization values.
Conclusion: As a result, the application of the dental toothpaste with ginger-honey content produced higher remineralization effect in all demineralization groups than the NaF toothpaste.
Keywords: Initial enamel lesion, Ginger, remineralization, ultrasound, Fluoresence.

Keywords

Initial enamel lesion, remineralization, ultrasound, Fluoresence.

Project Number

SAG-C-DUP-250416-0171

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