Coronavirus: A Biochemical Approach

Year 2021, , 66 - 77, 11.06.2021

Aysel Güven , Tülay Allahverdi , Özge Deniz Güven

https://doi.org/10.33484/sinopfbd.776394

Abstract

The purpose of this study is; to give information about the biological structure, metabolism and interaction of the Covid-19 agent virus with the defense system; to reveal the relationship between biochemical blood values and the defense system in Covid-19 cases and to update the data on preventing the damage that the virus may cause, in line with scientific developments. Relevant articles found by searching the keywords “SARS-CoV-2” and “Coronavirus” in Pubmed, Web of Science and Google Scholar databases and Google Search Engine were included in the study. This virus, called SARS-CoV-2, which originated in Vuhan, China and caused the disease called Covid-19, spread to almost all countries of the world and caused a high number of deaths in a very short time. Using the virus RNA, the infected cell begins to produce proteins that will keep the immune system at bay and help create new copies of the virus. For this reason, monitoring the disease and sharing information all over the world, epidemiological contact history, clinical features, biochemical tests in all blood and urine and other conditions are important evaluations for the treatments of the patient. It is imperative to follow the global situation and to make correct decisions according to the changes in epidemiology and to update the information of employees.

Keywords

SARS-CoV-2, Covid19, biochemical tests

Biyokimyasal Açıdan Koronavirüs

Abstract

Bu çalışmanın amacı; Covid-19 etkeni virüsün biyolojik yapısı, metabolizması ve savunma sistemiyle etkileşimi hakkında bilgi vermek; Covid-19 vakalarında biyokimyasal kan değerleri ile savunma sistemi ilişkilerini ve virüsün yaratabileceği tahribatları engellemek konusundaki verileri bilimsel gelişmeler doğrultusunda güncelleyerek ortaya koymaktır. Pubmed, Web of Science ve Google Scholar veri tabanlarında ve Google Arama Motorunda “SARS-CoV-2” ve “Coronavirus” anahtar kelimeleri aranarak bulunan ilgili makaleler çalışma kapsamına alınmıştır. Çin'in Wuhan kentinde ortaya çıkmış ve Covid-19 adı verilen hastalığa yol açan SARS-CoV-2 olarak adlandırılan bu virüs, dünyanın neredeyse bütün ülkelerine yayılmış ve çok kısa bir sürede yüksek sayıda ölümlere neden olmuştur. Enfekte olan hücre, virüs RNA’sını kullanarak, bağışıklık sistemini uzak tutacak ve virüsün yeni kopyalarını oluşturmaya yardımcı olacak proteinler üretmeye başlar. Süreç dinamiktir ve yeni keşifler ve değişiklikler her an olabilir. Bu nedenle tüm dünyada hastalığın izlenmesi ve bilginin paylaşılması, epidemiyolojik temas öyküsü, klinik özellikler, tüm kan ve idrarda biyokimyasal testler ve diğer durumlar hastanın tedavisi için önemli değerlendirmelerdir. Küresel durumun izlenmesi ve epidemiyolojideki değişimlere göre yerinde ve doğru kararlar alınması ve çalışanlarının bilgilerini güncellemeleri zorunludur.

Keywords

SARS-CoV-2, Covid19, biyokimya testleri

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