Kronik Hastalığı Olmayan Varikosel Tanılı Genç Erkek Hastalarda Kan Sayım Parametrelerinin Değerlendirilmesi

Abstract

Amaç: Varikosel pleksus pampiniformis içerisindeki testikuler venlerin anormal dilatasyonu olarak tanımlanan ve günümüzde erkeklerde infertiliteye neden olan en sık görülen hastalıklardan biridir. Çalışmamızın amacı varikosel tanısı alan hastalarda kan sayım parametrelerinin sağlıklı bireylerle karşılaştırılmasıdır. Gereç ve Yöntem: Ordu Üniversitesi Eğitim ve Araştırma Hastanesi üroloji polikliniğine Nisan 2014-Nisan 2019 tarihleri arasında müracaat eden hastalar retrospektif olarak değerlendirildi. Fizik muayenesinde Grade 3 varikosel tanısı konulan 163 hasta saptandı. Dahil etme kriterlerini karşılayan toplam 112 hasta kontrol grubu olarak çalışmaya alındı. Varikosel fizik muayene ile değerlendirildi. Elde edilen hemogram sonuçlarındaki beyaz kan hücresi, hemoglobin, Hematokrit, Platelet, Eritrosit, Nötrofil, Lenfosit, Monosit, Ortalama hemoglobin miktarı, Ortalama eritrosit hacmi (OEH), Eritrosit dağılım genişliği (EDG), Trombosit dağılım genişliği (TDG), Ortalama trombosit hacmi (OTH) değerleri karşılaştırıldı. Bulgular: Her iki grup arasında yaş ortalamaları açısından istatistiksel farklılık saptanmamıştır (p=0,370). Her iki grup arasında istatistiksel olarak anlamlı çıkan parametreler sırasıyla eritrosit (p=0,027), OEH (p=0,038), EDG (p=0,013) ve TDG (p=0,000)’dır. OTH değeri kontrol grubuna göre varikosel grubunda istatistiksel anlamlılık olmasa da rakamsal olarak kontrol grubuna göre yüksek bulunmuştur. Diğer parametreler ve oranlar arasında istatistiksel açıdan anlamlı bir farklılık saptanmamıştır. Sonuç: Çalışmamız varikoseli olan hastalarda eritrosit, TDG ve EDG değerlerinin daha yüksek olduğunu göstermektedir. Trombosit ve eritrosit aktivasyonunun, varikoselin patofizyolojik temelinde önemli bir rol oynayabileceğini düşünmekteyiz.

Keywords

• Varikosel
• Eritrosit
• Trombosit

Evaluation of Biochemical Parameters in Young Male Patients with Varicocele without Chronic Disease

Abstract

Objective: Varicocele is one of the most common causes of infertility in men today, which is defined as abnormal dilatation of testicular veins in plexus pampiniformis. The aim of our study was to compare blood count parameters with healthy subjects in patients with varicocele. Materials and Methods: Patients who applied to Ordu University Training and Research Hospital Urology Policlinic between April 2014 and April 2019 were evaluated retrospectively. In the physical examination, 163 patients with Grade 3 varicocele were diagnosed. A total of 112 patients who met the inclusion criteria were included as a control group in the study. Varicocele was evaluated by physical examination. Obtained hemogram results in white blood cell, hemoglobin, hematocrit, platelet, erythrocyte, neutrophil, lymphocyte, Monocyte, mean erythrocyte volume, average hemoglobin amount, erythrocyte distribution width (RDW), platelet distribution width (PDW), mean platelet volume (MPV) values were compared. Results: There is no statistically significant difference was found between the two groups in terms of the mean age (p = 0.370). The statistically significant parameters between the two groups were erythrocyte (p = 0.027), MCV (p = 0.038), RDW (p = 0.013) and PDW (p = 0.000), respectively. MPV values were higher in the varicocele group than the control group. There is no statistically significant difference was found between other parameters and rates. Conclusion: Our study shows that erythrocyte, PDW and RDW values are higher in patients with varicocele. We think that platelet and erythrocyte activation may play an important role in the pathophysiological basis of varicocele.

Keywords

• Varicocele
• Erythrocytes
• Platelet

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