TR
EN
Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*
Abstract
Foot and mouth disease (FMD) remains one of the most economically devastating transboundary animal diseases worldwide, affecting cloven hoofed animals including cattle, sheep, goats and pigs. Türkiye, due to its strategic geographical position bridging Europe and Asia, continues to face periodic challenges from FMD outbreaks. This review based study aims to provide a comprehensive overview of the clinical symptoms, diagnostic procedures, treatment protocols and prevention strategies currently employed against FMD in Türkiye. Emphasis is placed on the species specific clinical presentations, the importance of differential diagnosis and the integration of molecular diagnostics such as RT-PCR and ELISA in rapid disease confirmation. Supportive treatment options, including anti-inflammatory therapy, nutritional support and secondary infection control are discussed in light of field realities. Furthermore, Türkiye’s vaccination strategies and regional control programs are evaluated for their current effectiveness. The findings underscore the need for continuous veterinary training, improved surveillance systems and enhanced awareness among livestock owners to ensure timely response and reduce the socioeconomic burden of FMD.
Keywords
References
- Albayrak, H., Ozan, E., & Cavunt, A. (2013). A serological survey of selected pathogens in wild boar (Sus scrofa) in northern Türkeye. European Journal of Wildlife Research, 59(6), 893–897. https://doi.org/10.1007/s10344-013-0743-6 Accessed 15.06.2025
- Alexandersen, S., Zhang, Z., Donaldson, A. I., & Garland, A. J. (2003). The pathogenesis and diagnosis of foot-and-mouth disease. Journal of Comparative Pathology, 129(1), 1–36. https://doi.org/10.1016/S0021-9975(03)00041-0 Accessed 15.06.2025
- Alexandrov, T., et al. (2013). Surveillance of foot-and-mouth disease (FMD) in susceptible wildlife and domestic ungulates in Southeast of Bulgaria following a FMD case in wild boar. Veterinary Microbiology, 166(1–2), 84–90. https://doi.org/10.1016/j.vetmic.2013.05.016 Accessed 15.06.2025
- Alkhamis MA, Perez AM, Yadin H, Knowles NJ (2009) Temporospatial clustering of foot-and-mouth Disease outbreaks in Israel and Palestine, 2006–2007. Transbound Emerg Dis56(3):99–107.https://doi.org/10.1111/j.1865-1682.2009.01066.xAccessed 27.10.2025
- Anonymous (2025). Republic of Türkiye, Ministry of Agriculture and Forestry, Foot-and-Mouth Disease Institute (Şap Institute) https://vetkontrol.tarimorman.gov.tr/sap Accessed 08.12.2025
- Arzt, J., Juleff, N., Zhang, Z., & Rodriguez, L. L. (2011). The pathogenesis of foot-and-mouth disease I: Viral pathways in cattle. Transboundary and Emerging Diseases, 58(4), 291–304. https://doi.org/10.1111/j.1865-1682.2011.01204.x Accessed 15.06.2025
- Bastos, A. D., Haydon, D. T., Forsberg, R., Knowles, N. J., Anderson, E. C., Bengis, R. G., Nel, L. H., & Thomson, G. R. (2001). Genetic heterogeneity of SAT-1 type foot-and-mouth disease viruses in southern Africa. Archives of Virology, 146(8), 1537–1551. https://doi.org/10.1007/s007050170077 Accessed 15.06.2025
- Brown, C. C., & Torres, A. (2008). Foreign animal diseases. USAHA, Richmond, VA. Retrieved from https://homepage.uludag.edu.tr/~mufitk/op120072008guz/thegraybookanimald.pdf Accessed 15.06.2025
Details
Primary Language
English
Subjects
Agricultural Engineering (Other)
Journal Section
Review
Publication Date
December 23, 2025
Submission Date
September 10, 2025
Acceptance Date
November 8, 2025
Published in Issue
Year 2025 Number: 9
APA
Demir, A. Ö., & Hakan, S. (2025). Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*. Şırnak Üniversitesi Fen Bilimleri Dergisi, 9, 98-119. https://izlik.org/JA57BP75AG
AMA
1.Demir AÖ, Hakan S. Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*. Şırnak Üniversitesi Fen Bilimleri Dergisi. 2025;(9):98-119. https://izlik.org/JA57BP75AG
Chicago
Demir, Ayşe Özge, and Sinan Hakan. 2025. “Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*”. Şırnak Üniversitesi Fen Bilimleri Dergisi, nos. 9: 98-119. https://izlik.org/JA57BP75AG.
EndNote
Demir AÖ, Hakan S (December 1, 2025) Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*. Şırnak Üniversitesi Fen Bilimleri Dergisi 9 98–119.
IEEE
[1]A. Ö. Demir and S. Hakan, “Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*”, Şırnak Üniversitesi Fen Bilimleri Dergisi, no. 9, pp. 98–119, Dec. 2025, [Online]. Available: https://izlik.org/JA57BP75AG
ISNAD
Demir, Ayşe Özge - Hakan, Sinan. “Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*”. Şırnak Üniversitesi Fen Bilimleri Dergisi. 9 (December 1, 2025): 98-119. https://izlik.org/JA57BP75AG.
JAMA
1.Demir AÖ, Hakan S. Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*. Şırnak Üniversitesi Fen Bilimleri Dergisi. 2025;:98–119.
MLA
Demir, Ayşe Özge, and Sinan Hakan. “Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*”. Şırnak Üniversitesi Fen Bilimleri Dergisi, no. 9, Dec. 2025, pp. 98-119, https://izlik.org/JA57BP75AG.
Vancouver
1.Ayşe Özge Demir, Sinan Hakan. Clinical Manifestations, Diagnostic Approaches and Preventive Strategies for Foot-and-Mouth Disease (FMD) in Türkiye: A Contemporary Review*. Şırnak Üniversitesi Fen Bilimleri Dergisi [Internet]. 2025 Dec. 1;(9):98-119. Available from: https://izlik.org/JA57BP75AG