Research Article

Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM

Volume: 15 Number: 2 July 1, 2026
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Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM

Abstract

While deep learning models in medical imaging have gained popularity as a means to enhance patient outcomes and diagnostic accuracy recently, one of their main issues is interpretability, which is essential to understanding and debugging the model. Explainable Artificial Intelligence (XAI) is a recent rising research direction that aims to explain this black box part of the deep learning models. For quick identification, clinical evaluations and imaging methods such as Magnetic Resonance Imaging (MRI) scans, are frequently utilized; nevertheless, manual analysis has challenges such as subjectivity and delays. On the other hand, AI-based models convey a more rapid and reliable approach to classifying and detecting brain tumors. In this work, we present a transparent and explainable framework of pre-trained Convolutional Neural Network (CNN) models combined with Gradient Weighted Class Activation Mapping (Grad-CAM) for the classification of brain MRI images. We compare the effectiveness of ResNet50, DenseNet121, MobileNetV2 and ConvNeXtTiny architectures. We obtained a test accuracy of 100% and precision-recall scores above 99.90%, highlighting the model's effectiveness in identifying whether a tumor is present. The results illustrate how the models have enhanced localization skills by visualizing the regions of focus in the predictions through the application of the Grad-CAM method. This blend of interpretability offers a promising step toward creating more reliable and understandable tools for diagnosing brain tumors.

Keywords

References

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Details

Primary Language

English

Subjects

Biomedical Diagnosis, Electronics

Journal Section

Research Article

Publication Date

July 1, 2026

Submission Date

July 23, 2025

Acceptance Date

February 6, 2026

Published in Issue

Year 2026 Volume: 15 Number: 2

APA
Coskun, M. (2026). Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. Turkish Journal of Nature and Science, 15(2), 39-48. https://doi.org/10.46810/tdfd.1749282
AMA
1.Coskun M. Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. TJNS. 2026;15(2):39-48. doi:10.46810/tdfd.1749282
Chicago
Coskun, Musab. 2026. “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”. Turkish Journal of Nature and Science 15 (2): 39-48. https://doi.org/10.46810/tdfd.1749282.
EndNote
Coskun M (July 1, 2026) Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. Turkish Journal of Nature and Science 15 2 39–48.
IEEE
[1]M. Coskun, “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”, TJNS, vol. 15, no. 2, pp. 39–48, July 2026, doi: 10.46810/tdfd.1749282.
ISNAD
Coskun, Musab. “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”. Turkish Journal of Nature and Science 15/2 (July 1, 2026): 39-48. https://doi.org/10.46810/tdfd.1749282.
JAMA
1.Coskun M. Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. TJNS. 2026;15:39–48.
MLA
Coskun, Musab. “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”. Turkish Journal of Nature and Science, vol. 15, no. 2, July 2026, pp. 39-48, doi:10.46810/tdfd.1749282.
Vancouver
1.Musab Coskun. Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. TJNS. 2026 Jul. 1;15(2):39-48. doi:10.46810/tdfd.1749282