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Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM

Cilt: 15 Sayı: 2 1 Temmuz 2026
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Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM

Öz

While deep learning models in medical imaging have gained popularity as a means to enhance patient outcomes and diagnostic accuracy recently, one of their main issues is interpretability, which is essential to understanding and debugging the model. Explainable Artificial Intelligence (XAI) is a recent rising research direction that aims to explain this black box part of the deep learning models. For quick identification, clinical evaluations and imaging methods such as Magnetic Resonance Imaging (MRI) scans, are frequently utilized; nevertheless, manual analysis has challenges such as subjectivity and delays. On the other hand, AI-based models convey a more rapid and reliable approach to classifying and detecting brain tumors. In this work, we present a transparent and explainable framework of pre-trained Convolutional Neural Network (CNN) models combined with Gradient Weighted Class Activation Mapping (Grad-CAM) for the classification of brain MRI images. We compare the effectiveness of ResNet50, DenseNet121, MobileNetV2 and ConvNeXtTiny architectures. We obtained a test accuracy of 100% and precision-recall scores above 99.90%, highlighting the model's effectiveness in identifying whether a tumor is present. The results illustrate how the models have enhanced localization skills by visualizing the regions of focus in the predictions through the application of the Grad-CAM method. This blend of interpretability offers a promising step toward creating more reliable and understandable tools for diagnosing brain tumors.

Anahtar Kelimeler

Kaynakça

  1. H. ZainEldin et al., “Brain Tumor Detection and Classification Using Deep Learning and Sine-Cosine Fitness Grey Wolf Optimization,” Bioeng. Basel Switz., vol. 10, no. 1, p. 18, Dec. 2022, doi: 10.3390/bioengineering10010018.
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  4. S. Jayade, D. T. Ingole, and M. D. Ingole, “Review of Brain Tumor Detection Concept using MRI Images,” in 2019 International Conference on Innovative Trends and Advances in Engineering and Technology (ICITAET), Dec. 2019, pp. 206–209. doi: 10.1109/ICITAET47105.2019.9170144.
  5. W. Ayadi, W. Elhamzi, I. Charfi, and M. Atri, “Deep CNN for Brain Tumor Classification,” Neural Process. Lett., vol. 53, no. 1, pp. 671–700, Feb. 2021, doi: 10.1007/s11063-020-10398-2.
  6. M. Nazir, S. Shakil, and K. Khurshid, “Role of deep learning in brain tumor detection and classification (2015 to 2020): A review,” Comput. Med. Imaging Graph., vol. 91, p. 101940, Jul. 2021, doi: 10.1016/j.compmedimag.2021.101940.
  7. S. Saeedi, S. Rezayi, H. Keshavarz, and S. R. Niakan Kalhori, “MRI-based brain tumor detection using convolutional deep learning methods and chosen machine learning techniques,” BMC Med. Inform. Decis. Mak., vol. 23, no. 1, p. 16, Jan. 2023, doi: 10.1186/s12911-023-02114-6.
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Ayrıntılar

Birincil Dil

İngilizce

Konular

Biyomedikal Tanı, Elektronik

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

1 Temmuz 2026

Gönderilme Tarihi

23 Temmuz 2025

Kabul Tarihi

6 Şubat 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 15 Sayı: 2

Kaynak Göster

APA
Coskun, M. (2026). Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. Turkish Journal of Nature and Science, 15(2), 39-48. https://doi.org/10.46810/tdfd.1749282
AMA
1.Coskun M. Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. TDFD. 2026;15(2):39-48. doi:10.46810/tdfd.1749282
Chicago
Coskun, Musab. 2026. “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”. Turkish Journal of Nature and Science 15 (2): 39-48. https://doi.org/10.46810/tdfd.1749282.
EndNote
Coskun M (01 Temmuz 2026) Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. Turkish Journal of Nature and Science 15 2 39–48.
IEEE
[1]M. Coskun, “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”, TDFD, c. 15, sy 2, ss. 39–48, Tem. 2026, doi: 10.46810/tdfd.1749282.
ISNAD
Coskun, Musab. “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”. Turkish Journal of Nature and Science 15/2 (01 Temmuz 2026): 39-48. https://doi.org/10.46810/tdfd.1749282.
JAMA
1.Coskun M. Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. TDFD. 2026;15:39–48.
MLA
Coskun, Musab. “Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM”. Turkish Journal of Nature and Science, c. 15, sy 2, Temmuz 2026, ss. 39-48, doi:10.46810/tdfd.1749282.
Vancouver
1.Musab Coskun. Enhancing Reliability in Deep Learning Diagnosis of Brain Tumors Using Grad-CAM. TDFD. 01 Temmuz 2026;15(2):39-48. doi:10.46810/tdfd.1749282