Research Article

The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications

Volume: 52 February 17, 2026
TR EN

The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications

Abstract

This study aimed to evaluate the weight-loss efficacy, tolerability, and safety of intragastric balloon (IGB) therapy as a minimally invasive alternative for patients who do not undergo bariatric surgery. Between June 2022 and October 2024, liquid-filled IGBs were endoscopically placed in 56 patients (aged 18–65 years, BMI > 27 kg/m²) who had failed to lose weight through lifestyle modifications. Following the exclusion of cases involving intolerance and one patient who required early removal due to pregnancy, data from 51 patients (51% female; mean age 29.4 years; mean baseline BMI 34.8 kg/m²) were retrospectively analyzed at the 6-month follow-up. Results demonstrated significant weight loss, with mean weight decreasing from 103.4 kg to 89.3 kg (−14.1 kg), representing a 13.7% Total Body Weight Loss (TBWL) and 57.5% Excess Weight Loss (EWL). Optimal results were observed in the BMI 30–35 kg/m² subgroup (TBWL 17.4%, EWL 68.9%; p<0.05). While advancing age showed a statistically significant positive correlation with weight loss, this relationship was modest in clinical strength. The treatment was well-tolerated, with only a 7.2% intolerance rate and no major complications. In conclusion, IGB therapy is a safe and effective short-term intervention, providing optimal results in patients with a BMI of 30–35 kg/m² and showing a modest positive correlation with advancing age.

Keywords

Project Number

639

Ethical Statement

This study was conducted in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments. Ethical approval was obtained from the Gazi Yaşargil Training and Research Hospital Ethics Committee (Approval No: 639, Date: 19.09.2025). All participants provided written informed consent prior to inclusion in the study.

References

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Details

Primary Language

English

Subjects

Surgery (Other)

Journal Section

Research Article

Publication Date

February 17, 2026

Submission Date

October 21, 2025

Acceptance Date

February 8, 2026

Published in Issue

Year 2026 Volume: 52

APA
Elçi, M., & Ebik, B. (2026). The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications. Journal of Uludağ University Medical Faculty, 52, 1807960. https://doi.org/10.32708/uutfd.1807960
AMA
1.Elçi M, Ebik B. The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications. Journal of Uludağ University Medical Faculty. 2026;52:1807960. doi:10.32708/uutfd.1807960
Chicago
Elçi, Muhsin, and Berat Ebik. 2026. “The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications”. Journal of Uludağ University Medical Faculty 52 (February): 1807960. https://doi.org/10.32708/uutfd.1807960.
EndNote
Elçi M, Ebik B (February 1, 2026) The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications. Journal of Uludağ University Medical Faculty 52 1807960.
IEEE
[1]M. Elçi and B. Ebik, “The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications”, Journal of Uludağ University Medical Faculty, vol. 52, p. 1807960, Feb. 2026, doi: 10.32708/uutfd.1807960.
ISNAD
Elçi, Muhsin - Ebik, Berat. “The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications”. Journal of Uludağ University Medical Faculty 52 (February 1, 2026): 1807960. https://doi.org/10.32708/uutfd.1807960.
JAMA
1.Elçi M, Ebik B. The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications. Journal of Uludağ University Medical Faculty. 2026;52:1807960.
MLA
Elçi, Muhsin, and Berat Ebik. “The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications”. Journal of Uludağ University Medical Faculty, vol. 52, Feb. 2026, p. 1807960, doi:10.32708/uutfd.1807960.
Vancouver
1.Muhsin Elçi, Berat Ebik. The Role of Intragastric Balloon Application in Non-Surgical Management of Obesity: Efficacy, Tolerance, and Complications. Journal of Uludağ University Medical Faculty. 2026 Feb. 1;52:1807960. doi:10.32708/uutfd.1807960

ISSN: 1300-414X, e-ISSN: 2645-9027

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