Research Article

Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye

Volume: 52 October 13, 2026
TR EN

Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye

Abstract

Allergic Rhinitis has evolved beyond the conventional definition of nasal mucosal inflammation, becoming a complex ecosystem problem shaped by climate change and shifts in regional biodiversity. This study aimed to characterize aeroallergen sensitization patterns among adults with allergic rhinitis at a tertiary care center in Erzurum, Türkiye. This study was conducted as a single-center, retrospective, cross-sectional study at a tertiary allergy clinic in Erzurum, Türkiye. Patients aged 18 and over who presented to the immunology and allergy outpatient clinic with rhinitis complaints between November 2023 and January 2025 were retrospectively evaluated. Clinical, demographic, and laboratory data (including skin prick test results and serum allergen-specific immunoglobulin E levels) of the patients were obtained from the hospital's electronic medical records and patient files. A total of 1,235 patients presenting with rhinitis symptoms were retrospectively evaluated. After the initial clinical assessment and application of the eligibility and exclusion criteria, 739 patients were considered eligible for further evaluation. Of these, 496 patients (67.1%) who were sensitized to at least one aeroallergen (positive skin prick test and/or serum-specific immunoglobulin E) and in whom a diagnosis of allergic rhinitis was confirmed were included in the study group. 345 (69.6%) of the patients were female, and the median age was 27 (range: 18–69). A total of 306 patients (61.7%) were identified as monosensitized, with house dust mites n=183 (36.9%) and grass pollens n=159 (32.1%) as the most common allergens. The most frequent comorbid atopic disease was asthma (68/496 13.7%), and house dust mites were the most frequent aeroallergen sensitization among patients with asthma, detected in 31 patients (45.6%). In high-altitude Erzurum, featuring a harsh continental climate, house dust mites and grass pollen are the primary aeroallergens. The high rate of monosensitization in our study is noteworthy in terms of developing region-specific environmental control strategies and treatments in the management of allergic rhinitis.

Keywords

References

  1. 1. Allerji U, Society TN, Immunology C. Türkiye Ulusal Alerji ve Klinik İmmünoloji Derneği Alerjik Rinit Tanı ve Tedavi Rehberi.; 2022.
  2. 2. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, Zuberbier T, Canonica GW, Weel C Van, Agache I, Bachert C. Review article Allergic Rhinitis and its Impact on Asthma ( ARIA ) 2008 * Review Group : Prim Care. 2008;63:8-160.
  3. 3. Golden DBK. Insect Allergy.; 2022. doi:10.1016/B978-0-323-80912-2.00015-9
  4. 4. Kothandarama K, Mohindra S, Arungovind K, Mahendru S. Prevelance of Common Aeroallergens in Allergic Rhinitis and its Correlation with Bronchial Asthma: A Study on 798 Patients by Skin Prick Test. Indian J Otolaryngol Head Neck Surg. 2023;75(3):1651-1659. doi:10.1007/s12070-023-03643-2
  5. 5. Katelaris CH, Lee BW, Potter PC, Maspero JF, Cingi C, Lopatin A, Saffer M, Xu G, Walters RD. Prevalence and diversity of allergic rhinitis in regions of the world beyond Europe and North America. Clin Exp Allergy. 2012;42(2):186-207. doi:10.1111/j.1365-2222.2011.03891.x
  6. 6. Savouré M, Bousquet J, Jaakkola JJK, Jaakkola MS, Jacquemin B, Nadif R. Worldwide prevalence of rhinitis in adults: A review of definitions and temporal evolution. Clin Transl Allergy. 2022;12(3):1-10. doi:10.1002/clt2.12130
  7. 7. Brożek JL, Bousquet J, Agache I, Agarwal A, Bachert C, Bosnic-Anticevich S, Brignardello-Petersen R, Canonica GW, Schünemann HJ, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines—2016 revision. J Allergy Clin Immunol. 2017;140(4):950-958. doi:10.1016/j.jaci.2017.03.050
  8. 8. Agache I, Akdis C, Akdis M, Al-Hemoud A, Annesi-Maesano I, Balmes J, Cecchi L, Damialis A, Haahtela T, Haber AL, HartJE, Jutel M, Mitamura Y, Mmbaga BT, Oh JW,Ostadtaghizadeh A, Pawankar R, Johnson M, Renz H, RiceMB, Filho NAR, Sampath V, Skevaki C, Thien F, Traidl-Hoffmann C, Wong GWK, Nadeau KC. Climate change and allergic diseases: A scoping review. J Clim Chang Heal.2024;20:100350. doi:10.1016/j.joclim.2024.100350

Details

Primary Language

English

Subjects

Allergy

Journal Section

Research Article

Publication Date

October 13, 2026

Submission Date

July 29, 2026

Acceptance Date

September 25, 2026

Published in Issue

Year 2026 Volume: 52

APA
Bülbül, E. N., & Gül, Ö. (2026). Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye. Journal of Uludağ University Medical Faculty, 52. https://doi.org/10.32708/uutfd.2005618
AMA
1.Bülbül EN, Gül Ö. Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye. J Uludag Univ Med Fac. 2026;52. doi:10.32708/uutfd.2005618
Chicago
Bülbül, Esra Nur, and Özcan Gül. 2026. “Aeroallergen Sensitization Patterns Among Adults With Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye”. Journal of Uludağ University Medical Faculty 52 (October). https://doi.org/10.32708/uutfd.2005618.
EndNote
Bülbül EN, Gül Ö (October 1, 2026) Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye. Journal of Uludağ University Medical Faculty 52
IEEE
[1]E. N. Bülbül and Ö. Gül, “Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye”, J Uludag Univ Med Fac, vol. 52, Oct. 2026, doi: 10.32708/uutfd.2005618.
ISNAD
Bülbül, Esra Nur - Gül, Özcan. “Aeroallergen Sensitization Patterns Among Adults With Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye”. Journal of Uludağ University Medical Faculty 52 (October 1, 2026). https://doi.org/10.32708/uutfd.2005618.
JAMA
1.Bülbül EN, Gül Ö. Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye. J Uludag Univ Med Fac. 2026;52. doi:10.32708/uutfd.2005618.
MLA
Bülbül, Esra Nur, and Özcan Gül. “Aeroallergen Sensitization Patterns Among Adults With Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye”. Journal of Uludağ University Medical Faculty, vol. 52, Oct. 2026, doi:10.32708/uutfd.2005618.
Vancouver
1.Esra Nur Bülbül, Özcan Gül. Aeroallergen Sensitization Patterns Among Adults with Allergic Rhinitis at a Tertiary Center in Erzurum, Türkiye. J Uludag Univ Med Fac. 2026 Oct. 1;52. doi:10.32708/uutfd.2005618

ISSN: 1300-414X, e-ISSN: 2645-9027

Creative Commons License
Journal of Uludag University Medical Faculty is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
2023