Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats

Volume: 30 Number: 3 September 1, 2004
  • Gülnur Take
  • Gülten Karabay
  • A. Canan Yazıcı
  • Deniz Erdoğan
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Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats

Abstract

The aim of this study was to analyze the ultrastructural alterations in ventricular cardiac muscle cells in female rats in which chronic diabetes was induced with streptozotocin. Mature female rats (n=18) were assigned into 3 groups: Group 1: the controls (n=6), Group 2: the sham controls (n=6), and Group 3: the diabetic (n=6). Eight weeks after injection, left ventricle muscles were extracted and examined with a LEO 906E transmission electron microscope. The electron microscopic analyses of the left ventricle wall revieled prominent degenerative alterations in the myocardial cells of diabetic rats. Swelling and crystolysis in the mitochondria, lipid deposition in the cytoplasm, and widespread effecement of myofilaments were detected. The Z bands were irregular and effacement was noted. In edition, the intercalated discs were dilated. As a result, it can be suggest that females are affected at the early stages of diabetes mellitus.

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Primary Language

English

Subjects

-

Journal Section

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Authors

Gülnur Take This is me

Gülten Karabay This is me

A. Canan Yazıcı This is me

Deniz Erdoğan This is me

Publication Date

September 1, 2004

Submission Date

September 1, 2004

Acceptance Date

-

Published in Issue

Year 2004 Volume: 30 Number: 3

IZ

https://izlik.org/JA85GE79RJ

Cite

RIS / Bibtex
APA
Take, G., Karabay, G., Yazıcı, A. C., & Erdoğan, D. (2004). Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Journal of Uludağ University Medical Faculty, 30(3), 199-204. https://izlik.org/JA85GE79RJ
AMA
1.Take G, Karabay G, Yazıcı AC, Erdoğan D. Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Journal of Uludağ University Medical Faculty. 2004;30(3):199-204. https://izlik.org/JA85GE79RJ
Chicago
Take, Gülnur, Gülten Karabay, A. Canan Yazıcı, and Deniz Erdoğan. 2004. “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”. Journal of Uludağ University Medical Faculty 30 (3): 199-204. https://izlik.org/JA85GE79RJ.
EndNote
Take G, Karabay G, Yazıcı AC, Erdoğan D (September 1, 2004) Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Journal of Uludağ University Medical Faculty 30 3 199–204.
IEEE
[1]G. Take, G. Karabay, A. C. Yazıcı, and D. Erdoğan, “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”, Journal of Uludağ University Medical Faculty, vol. 30, no. 3, pp. 199–204, Sept. 2004, [Online]. Available: https://izlik.org/JA85GE79RJ
ISNAD
Take, Gülnur - Karabay, Gülten - Yazıcı, A. Canan - Erdoğan, Deniz. “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”. Journal of Uludağ University Medical Faculty 30/3 (September 1, 2004): 199-204. https://izlik.org/JA85GE79RJ.
JAMA
1.Take G, Karabay G, Yazıcı AC, Erdoğan D. Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Journal of Uludağ University Medical Faculty. 2004;30:199–204.
MLA
Take, Gülnur, et al. “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”. Journal of Uludağ University Medical Faculty, vol. 30, no. 3, Sept. 2004, pp. 199-04, https://izlik.org/JA85GE79RJ.
Vancouver
1.Gülnur Take, Gülten Karabay, A. Canan Yazıcı, Deniz Erdoğan. Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Journal of Uludağ University Medical Faculty [Internet]. 2004 Sep. 1;30(3):199-204. Available from: https://izlik.org/JA85GE79RJ

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