Dişi Sıçanlarda Streptozotosin İle Oluşturulmuş Diyabetin Kalp Kası Üzerine Etkisinin Ultrastrüktürel Düzeyde Gösterilmesi

Cilt: 30 Sayı: 3 1 Eylül 2004
  • Gülnur Take
  • Gülten Karabay
  • A. Canan Yazıcı
  • Deniz Erdoğan
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Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats

Öz

The aim of this study was to analyze the ultrastructural alterations in ventricular cardiac muscle cells in female rats in which chronic diabetes was induced with streptozotocin. Mature female rats (n=18) were assigned into 3 groups: Group 1: the controls (n=6), Group 2: the sham controls (n=6), and Group 3: the diabetic (n=6). Eight weeks after injection, left ventricle muscles were extracted and examined with a LEO 906E transmission electron microscope. The electron microscopic analyses of the left ventricle wall revieled prominent degenerative alterations in the myocardial cells of diabetic rats. Swelling and crystolysis in the mitochondria, lipid deposition in the cytoplasm, and widespread effecement of myofilaments were detected. The Z bands were irregular and effacement was noted. In edition, the intercalated discs were dilated. As a result, it can be suggest that females are affected at the early stages of diabetes mellitus.

Anahtar Kelimeler

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

-

Yazarlar

Gülnur Take Bu kişi benim

Gülten Karabay Bu kişi benim

A. Canan Yazıcı Bu kişi benim

Deniz Erdoğan Bu kişi benim

Yayımlanma Tarihi

1 Eylül 2004

Gönderilme Tarihi

1 Eylül 2004

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2004 Cilt: 30 Sayı: 3

IZ

https://izlik.org/JA85GE79RJ

Kaynak Göster

RIS / Bibtex
APA
Take, G., Karabay, G., Yazıcı, A. C., & Erdoğan, D. (2004). Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Journal of Uludağ University Medical Faculty, 30(3), 199-204. https://izlik.org/JA85GE79RJ
AMA
1.Take G, Karabay G, Yazıcı AC, Erdoğan D. Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Uludağ Tıp Derg. 2004;30(3):199-204. https://izlik.org/JA85GE79RJ
Chicago
Take, Gülnur, Gülten Karabay, A. Canan Yazıcı, ve Deniz Erdoğan. 2004. “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”. Journal of Uludağ University Medical Faculty 30 (3): 199-204. https://izlik.org/JA85GE79RJ.
EndNote
Take G, Karabay G, Yazıcı AC, Erdoğan D (01 Eylül 2004) Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Journal of Uludağ University Medical Faculty 30 3 199–204.
IEEE
[1]G. Take, G. Karabay, A. C. Yazıcı, ve D. Erdoğan, “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”, Uludağ Tıp Derg, c. 30, sy 3, ss. 199–204, Eyl. 2004, [çevrimiçi]. Erişim adresi: https://izlik.org/JA85GE79RJ
ISNAD
Take, Gülnur - Karabay, Gülten - Yazıcı, A. Canan - Erdoğan, Deniz. “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”. Journal of Uludağ University Medical Faculty 30/3 (01 Eylül 2004): 199-204. https://izlik.org/JA85GE79RJ.
JAMA
1.Take G, Karabay G, Yazıcı AC, Erdoğan D. Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Uludağ Tıp Derg. 2004;30:199–204.
MLA
Take, Gülnur, vd. “Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats”. Journal of Uludağ University Medical Faculty, c. 30, sy 3, Eylül 2004, ss. 199-04, https://izlik.org/JA85GE79RJ.
Vancouver
1.Gülnur Take, Gülten Karabay, A. Canan Yazıcı, Deniz Erdoğan. Ultrastructural Demonstration Of The Effects Of Streptozotocin-Induced Diyabetes On Heart Muscle In Female Rats. Uludağ Tıp Derg [Internet]. 01 Eylül 2004;30(3):199-204. Erişim adresi: https://izlik.org/JA85GE79RJ

ISSN: 1300-414X, e-ISSN: 2645-9027

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