The Biological Activities, Applications and Effects of Saponin Component

Yıl 2022, Cilt: 15 Sayı: 2, 164 - 173, 31.08.2022

Emine Okumuş , Mehmet Ali Temiz

https://doi.org/10.52976/vansaglik.1028378

Öz

Saponin Bileşeninin Biyolojik Aktiviteleri, Kullanım Alanları ve Etkileri

Öz

Tarih boyunca bitkiler insanlar tarafından birçok hastalığın tedavisinde kullanılırken, son yıllarda yapılan çok sayıdaki in vivo, in vitro ve in silico çalışmalarda, bitkilerin yapısında tıbbi olarak yararlı etkiler gösteren çeşitli bileşenler olduğu bilimsel olarak da ortaya konmuştur. Saponinler, geniş bir farmakolojik ve endüstriyel potansiyele sahip olan bitkilerin sekonder metabolit ürünleridir. Uzun yıllar boyunca saponinlerin sağlığa zararlı etkilerinin olduğu düşünülmüş olmasına rağmen, yapılan çalışmalarda uygulama dozu ve uygulama sıklığına bağlı olarak yararlı etkilerinin olabileceği belirlenmiştir. Farmakolojik araştırmalar, saponinlerin antidiyabetik, sitotoksik, antibakteriyel, kolesterol düşürücü, antifungal ve anti-inflamatuar aktiviteler sergilediğini ve birçok farklı alanda faydalı olduğunu ortaya koymuştur. Oluşturulan bu derleme, saponin bileşeni hakkında bilgi vermek ve bu bileşeninin biyolojik aktiviteleri ile saponin içeren bitki ve gıdaların kullanımının sağlık üzerinde meydana getirdiği etkiler, yapılan bilimsel çalışmalar örnek gösterilerek açıklanmak üzere hazırlanmıştır.

Anahtar Kelimeler

Biyolojik aktivite, Sağlığa etki, Saponin

Kaynakça

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