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Obstructive sleep apnea syndrome and erectile dysfunction

Year 2016, Volume: 11 Issue: 3, 6 - 9, 01.08.2016

Abstract

Objective: Obstructive Sleep Apnea Syndrome OSAS , which characterized recurrent upper respiratory tract collapse, is shown over 40 years old men in more than 10% incidence, which cause erectile dysfunction that not clearly defined, in 30% with 50% of these men have OSAS. In this study we have tried to reveal the relationship OSAS and ED because of unclear multifactorial etiology. Material and Methods: We have examined 70 patients who could not be treated because of erectile dysfunction; demographic information, gonadal function, lower urinary tract symptoms, comorbidity index and IIEF International Index of Erectile Function -15 form for erectile dysfunction, who applied for sleep disturbance and testing polisomnograpy at polisomnograpy laboratuary. Results: The polysomnographic findings by obstructive sleep apnea degree of patients classified by grouping IIEF-15 form and evaluated within the framework specified parameters with sleep apnea syndrome were found to have significant association between erectile dysfunction p

References

  • Kochar MS, Mazur LI, Patel A et al. (1999) What is causing your patient’s sexual dysfunction? Uncovering a connection with hypertension and antihypertensive therapy. Postgrad Med 106:149–152, 155–147.
  • Hirshkowitz M, Karacan I, Arcasoy MO et al. Prevalen- ce of sleep apnea in men with erectile dysfunction. Uro- logy 1990;36:232-4.
  • Young T. Pepard PE, Gottlied DJ et al. Epidemyology of obs- tructive sleep apne; a population health perspective, Am J Respir Crit, CarecMed 2002;165:1217-39.
  • Pressman, M.R. et al Problems in the interpretation of noc- turnal penile tumescence studies: disruption of sleep by oc- cult sleep disorders. J Urol 1986;136:595.
  • Fanfulla F, Malaguti S, Montagna T et al. Erectile dysfunc- tion in men with obstructive sleep apnea: an early sign of nerve involvement. Sleep 2000; 23: 775–81.
  • Margel D, Cohen M, Livne PM et al. but not mild, obstructi- ve sleep apnea syndrome is associated with erectile dysfunc- tion. Urology 2004; 63: 545–9.
  • Guilleminault C, Eldridge FL, Tilkian A et al. Sleep apnea syndrome due to upper airway obstruction. A review of 25 cases. Arch Intern Med 1977; 137: 296–300.
  • Feldman HA, Johannes CB, Derby CA et al. Erectile dysfunction and coronary risk factors, prospective re- sults from the Massachusetts male aging study. Prev Med 2000;30: 328–338.
  • Fanfulla F, Malaguti S, Montagna T et al. Erectile dysfunc- tion in men with obstructive sleep apnea: an early sign of nerve involvement. Sleep 2000; 23: 775–81.
  • Ip MS, Lam B, Chan LY et al. Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by na- sal continuous positive airway pressure.
  • McKenna KE. Neural circuitry involved in sexual function. J Spinal Cord Med 2001;24:148-54.
  • Soukhova-O Hare GK, Shah ZA, Lei Z et al. Erectile dysfunction in a murine model of sleep apnea. Am J Respir Crit Care Med 2008; 178:644-50.
  • Roizenblatt S, Guilleminault C, Poyars D et al. A dub- le blind, placebo controlled, crossover study of silde- nafil in obstructive sleep apnea. Arc intern Med 2006 166:1763-1767.14-Kennedy SH, Rizvi S et al. Sexual dysfunction, depression, and the impact of antidepressants. J Clin Psychopharmacol 2009;29:157-64.

Obstruktif uyku apne sendromu ve erektil disfonksiyon

Year 2016, Volume: 11 Issue: 3, 6 - 9, 01.08.2016

Abstract

Amaç: Tekrarlayan üst solunum yolu kollapsı ile karakterize olan Obstruktif Uyku Apne Sendromu OSAS , 40’lı yaşlarını geçmiş erkeklerin %10’undan fazlasında gösterilmiş olup bu erkeklerin %30 ile 50’sinde sebebi tam açıklanamamış erektil disfonksiyon görülmektedir. Bu çalışmamızda etiyolojisi netlik kazanmamış multifaktöryel nedenlere bağlı olduğu düşünülen OSAS ve ED ilişkisi ortaya konulmaya çalışılmıştır. Gereç ve Yöntem: Uyku bozukluğu nedeniyle Kulak Burun Boğaz hastalıkları obstruktif uyku apne bozukluğu polikliniğine başvurusu sonrası polisomnografik testleri yapılan , erektil disfonksiyon nedeniyle tedavi olamamış 70 hastanın demografik bilgileri, gonadal fonksiyonları, alt üriner sistem semptom sorguları, komorbidite indeksleri ve IIEF International Index of Erectile Function -15 sorgu formları eşliğinde erektil disfonksiyon açısından sorgulanmıştır. Bulgular: Polisomnografik bulgularına göre obstruktif sleep apne derecesi sınıflandırılan hastalar gruplandırılarak IIEF-15 formu ve belirtilen parametreler çerçevesinde değerlendirildiğinde uyku apne sendromu ile erektil disfonksiyon arasında anlamlı ilişki olduğu saptandı p

References

  • Kochar MS, Mazur LI, Patel A et al. (1999) What is causing your patient’s sexual dysfunction? Uncovering a connection with hypertension and antihypertensive therapy. Postgrad Med 106:149–152, 155–147.
  • Hirshkowitz M, Karacan I, Arcasoy MO et al. Prevalen- ce of sleep apnea in men with erectile dysfunction. Uro- logy 1990;36:232-4.
  • Young T. Pepard PE, Gottlied DJ et al. Epidemyology of obs- tructive sleep apne; a population health perspective, Am J Respir Crit, CarecMed 2002;165:1217-39.
  • Pressman, M.R. et al Problems in the interpretation of noc- turnal penile tumescence studies: disruption of sleep by oc- cult sleep disorders. J Urol 1986;136:595.
  • Fanfulla F, Malaguti S, Montagna T et al. Erectile dysfunc- tion in men with obstructive sleep apnea: an early sign of nerve involvement. Sleep 2000; 23: 775–81.
  • Margel D, Cohen M, Livne PM et al. but not mild, obstructi- ve sleep apnea syndrome is associated with erectile dysfunc- tion. Urology 2004; 63: 545–9.
  • Guilleminault C, Eldridge FL, Tilkian A et al. Sleep apnea syndrome due to upper airway obstruction. A review of 25 cases. Arch Intern Med 1977; 137: 296–300.
  • Feldman HA, Johannes CB, Derby CA et al. Erectile dysfunction and coronary risk factors, prospective re- sults from the Massachusetts male aging study. Prev Med 2000;30: 328–338.
  • Fanfulla F, Malaguti S, Montagna T et al. Erectile dysfunc- tion in men with obstructive sleep apnea: an early sign of nerve involvement. Sleep 2000; 23: 775–81.
  • Ip MS, Lam B, Chan LY et al. Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by na- sal continuous positive airway pressure.
  • McKenna KE. Neural circuitry involved in sexual function. J Spinal Cord Med 2001;24:148-54.
  • Soukhova-O Hare GK, Shah ZA, Lei Z et al. Erectile dysfunction in a murine model of sleep apnea. Am J Respir Crit Care Med 2008; 178:644-50.
  • Roizenblatt S, Guilleminault C, Poyars D et al. A dub- le blind, placebo controlled, crossover study of silde- nafil in obstructive sleep apnea. Arc intern Med 2006 166:1763-1767.14-Kennedy SH, Rizvi S et al. Sexual dysfunction, depression, and the impact of antidepressants. J Clin Psychopharmacol 2009;29:157-64.
There are 13 citations in total.

Details

Primary Language Turkish
Journal Section Original Article
Authors

Mustafa Gürkan Yenice This is me

Murat Tuncer This is me

Kubilay Sabuncu This is me

Selçuk Şahin This is me

Volkan Tuğcu This is me

Kemal Sarıca This is me

Ali İhsan Taşçı This is me

İsmail Yiğitbaşı This is me

Sadi Konuk This is me

Publication Date August 1, 2016
Published in Issue Year 2016 Volume: 11 Issue: 3

Cite

Vancouver Yenice MG, Tuncer M, Sabuncu K, Şahin S, Tuğcu V, Sarıca K, et al. Obstruktif uyku apne sendromu ve erektil disfonksiyon. New J Urol. 2016;11(3):6-9.