Case Report
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LAMOTRIGİNE INDUCED PROBABLE DRESS SYNDROME: CASE REPORT

Year 2020, , 168 - 170, 30.09.2020
https://doi.org/10.16948/zktipb.613162

Abstract

Drug reaction with
eosinophilia and systemic symptoms (DRESS Syndrome) is a rare,
life-threatening, drug- induced hypersensitivity reaction that include skin
eruptions, hematologic abnormalities (eosinophilia, atypical lymphocytosis),
lymphadenopathy and internal organ involvement (liver, kidney, lung). We
present an adolescent girl with probable DRESS Syndrome who had rash and fever
after having been treated with lamotrigine as antiepileptic drug before
fourteen days.  

References

  • 1-Shear NH, Spielberg SP. Anconvulsant hypersensitivity syndrome. In vitro assessment of risk. J Clin Invest 1988; 82 (6):1826-32.
  • 2-Halevy S, Feuerman EJ. Pseudolymphoma syndrome.Dermatologica 1977;155: 321.
  • 3-Kardaun SH, Sidoroff A, Valeyrie-Allanore L, Liss Y, Chu CY, Creamer D, ve ark. Drug reaction with eosinophilia and systemic symptoms(DRESS): an original multisystem advers drug reaction.Results from the prospective RegiSCAR study. Br J Dermatol 2013; 169(5):1071-80.
  • 4-Wang XQ, Lv B, Zhang X, Yu Sy, Huang XS, Zhang JT, ve ark.Lamotrigine induced DIHS/ DRESS: Manifestations, treatment, and outcome in 57 patients. Clin Neurol Neurosurg 2015; 138:1-7.
  • 5-Büyüköztürk S, Kekik Ç, Gökyiğit AZ, Tezer Filik FI, Karakaya G, Saygı S, ve ark. Cutaneous drug reactions to antiepileptic drugs and relation with HLA alleles in the Turkish population. Eur Ann Allergy Clin Immunol 2018; 50(1): 36-41.
  • 6-De Luca F, Losappio LM, Mirone C, Schroeder JW, Citterio A, Aversano MG, ve ark. Tolerated drugs in subjects with severe cutaneous adverse reactions (SCARs) induced by anticonvulsants and review of the literature. Clin Mol Allergy 2017;15:16. doi: 10.1186/s12948-017-0072-5. eCollection 2017
  • 7-Ramirez E, Medrano-Casique N, Tong Hy, Bellon T, Cabanas R, Fiandor A, ve ark. Eosinophilic drug reactions detected by a prospective pharmacovigilance programme in a tertiary hospital. BR J Clin Pharmacol 2017; 83(2): 400-415.
  • 8-Sasidhararnpillai S, Sabitha S, Riyaz N, Binitha MP, Muhammed K, Riyaz A, ve ark. Drug reaction with eosinophilia anda systemic symptoms in children: a prospective study. Pediatr Dermatol 2016; 33(2):e162-5. Doi: 10.1111/pde.12803.
  • 9-Erdem SB, Nacaroglu HT, Bag O, Karkiner CS, Korkmaz HA, Can D. DRESS Syndrome associated with type 2 diabetes in a child. Cent Eur J Immunol 2015; 40(4):493-6.
  • 10-Yazıcıoğlu M. Çocukluk çağında ilaç alerjilerine yaklaşım. Türk Ped Arş 2014; 49: 99-103.
  • 11-Brockow K, Romano A, Blanca M, Ring J, Pichler W, Demoly P. General considerations for skin test procedures in the diagnosis of drug hypersensitivity. Allergy 2002; 57(1): 45-51.
  • 12-Aberer W, Bircher A, Romano A, Blanca M, Campi P, Fernandez J, et al. Drug provocation testing in the diagnosis of drug hypersensitivity reactions. Allergy 2003; 58 (9): 854-63.
  • 13-Funck-Brentano E, Duong TA, Bouvresse S, Bagot M, Wolkenstein P, Roujeau JC, et al. Therapeutic management of DRESS: a retrospective study of 38 cases. J Am Acad Dermatol 2015; 72 (2): 246-252.
  • 14-Kaykı G, Özsürekçi Y, Arslanoğlu E, Akın MŞ, Saçkesen C, Orhan D, et al. DRESS Sendromu: Bir olgu sunumu. J Pediatr Inf 2016; 10: 99-103.

LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU

Year 2020, , 168 - 170, 30.09.2020
https://doi.org/10.16948/zktipb.613162

Abstract

DRESS Sendromu (Drug
Rush with Eosinophilia and Systemic Symptoms) ilaç ilişkili döküntü,
  hematolojik anormallikler (eozinofili, atipik
lenfositoz), lenfadenopati, iç organ tutulumları (karaciğer, böbrek, akciğer) ile
seyreden nadir, hayatı tehdit edebilen hipersensitivite reaksiyonudur. Antiepileptik
lamotrigin tedavisi başlandıktan on dört gün sonra döküntüsü ve ateşi gelişen
DRESS Sendromu olduğu düşünülen ergen bir kız hastayı sunduk.


References

  • 1-Shear NH, Spielberg SP. Anconvulsant hypersensitivity syndrome. In vitro assessment of risk. J Clin Invest 1988; 82 (6):1826-32.
  • 2-Halevy S, Feuerman EJ. Pseudolymphoma syndrome.Dermatologica 1977;155: 321.
  • 3-Kardaun SH, Sidoroff A, Valeyrie-Allanore L, Liss Y, Chu CY, Creamer D, ve ark. Drug reaction with eosinophilia and systemic symptoms(DRESS): an original multisystem advers drug reaction.Results from the prospective RegiSCAR study. Br J Dermatol 2013; 169(5):1071-80.
  • 4-Wang XQ, Lv B, Zhang X, Yu Sy, Huang XS, Zhang JT, ve ark.Lamotrigine induced DIHS/ DRESS: Manifestations, treatment, and outcome in 57 patients. Clin Neurol Neurosurg 2015; 138:1-7.
  • 5-Büyüköztürk S, Kekik Ç, Gökyiğit AZ, Tezer Filik FI, Karakaya G, Saygı S, ve ark. Cutaneous drug reactions to antiepileptic drugs and relation with HLA alleles in the Turkish population. Eur Ann Allergy Clin Immunol 2018; 50(1): 36-41.
  • 6-De Luca F, Losappio LM, Mirone C, Schroeder JW, Citterio A, Aversano MG, ve ark. Tolerated drugs in subjects with severe cutaneous adverse reactions (SCARs) induced by anticonvulsants and review of the literature. Clin Mol Allergy 2017;15:16. doi: 10.1186/s12948-017-0072-5. eCollection 2017
  • 7-Ramirez E, Medrano-Casique N, Tong Hy, Bellon T, Cabanas R, Fiandor A, ve ark. Eosinophilic drug reactions detected by a prospective pharmacovigilance programme in a tertiary hospital. BR J Clin Pharmacol 2017; 83(2): 400-415.
  • 8-Sasidhararnpillai S, Sabitha S, Riyaz N, Binitha MP, Muhammed K, Riyaz A, ve ark. Drug reaction with eosinophilia anda systemic symptoms in children: a prospective study. Pediatr Dermatol 2016; 33(2):e162-5. Doi: 10.1111/pde.12803.
  • 9-Erdem SB, Nacaroglu HT, Bag O, Karkiner CS, Korkmaz HA, Can D. DRESS Syndrome associated with type 2 diabetes in a child. Cent Eur J Immunol 2015; 40(4):493-6.
  • 10-Yazıcıoğlu M. Çocukluk çağında ilaç alerjilerine yaklaşım. Türk Ped Arş 2014; 49: 99-103.
  • 11-Brockow K, Romano A, Blanca M, Ring J, Pichler W, Demoly P. General considerations for skin test procedures in the diagnosis of drug hypersensitivity. Allergy 2002; 57(1): 45-51.
  • 12-Aberer W, Bircher A, Romano A, Blanca M, Campi P, Fernandez J, et al. Drug provocation testing in the diagnosis of drug hypersensitivity reactions. Allergy 2003; 58 (9): 854-63.
  • 13-Funck-Brentano E, Duong TA, Bouvresse S, Bagot M, Wolkenstein P, Roujeau JC, et al. Therapeutic management of DRESS: a retrospective study of 38 cases. J Am Acad Dermatol 2015; 72 (2): 246-252.
  • 14-Kaykı G, Özsürekçi Y, Arslanoğlu E, Akın MŞ, Saçkesen C, Orhan D, et al. DRESS Sendromu: Bir olgu sunumu. J Pediatr Inf 2016; 10: 99-103.
There are 14 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Case Report
Authors

Nihan Uygur Külcü

Özlem Erdede

Mahmut Doğru This is me

Gökçe Ezgi Eraslan This is me

Erdal Sarı

Feyza Yıldız

Publication Date September 30, 2020
Published in Issue Year 2020

Cite

APA Uygur Külcü, N., Erdede, Ö., Doğru, M., Eraslan, G. E., et al. (2020). LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU. Zeynep Kamil Tıp Bülteni, 51(3), 168-170. https://doi.org/10.16948/zktipb.613162
AMA Uygur Külcü N, Erdede Ö, Doğru M, Eraslan GE, Sarı E, Yıldız F. LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU. Zeynep Kamil Tıp Bülteni. September 2020;51(3):168-170. doi:10.16948/zktipb.613162
Chicago Uygur Külcü, Nihan, Özlem Erdede, Mahmut Doğru, Gökçe Ezgi Eraslan, Erdal Sarı, and Feyza Yıldız. “LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU”. Zeynep Kamil Tıp Bülteni 51, no. 3 (September 2020): 168-70. https://doi.org/10.16948/zktipb.613162.
EndNote Uygur Külcü N, Erdede Ö, Doğru M, Eraslan GE, Sarı E, Yıldız F (September 1, 2020) LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU. Zeynep Kamil Tıp Bülteni 51 3 168–170.
IEEE N. Uygur Külcü, Ö. Erdede, M. Doğru, G. E. Eraslan, E. Sarı, and F. Yıldız, “LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU”, Zeynep Kamil Tıp Bülteni, vol. 51, no. 3, pp. 168–170, 2020, doi: 10.16948/zktipb.613162.
ISNAD Uygur Külcü, Nihan et al. “LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU”. Zeynep Kamil Tıp Bülteni 51/3 (September 2020), 168-170. https://doi.org/10.16948/zktipb.613162.
JAMA Uygur Külcü N, Erdede Ö, Doğru M, Eraslan GE, Sarı E, Yıldız F. LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU. Zeynep Kamil Tıp Bülteni. 2020;51:168–170.
MLA Uygur Külcü, Nihan et al. “LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU”. Zeynep Kamil Tıp Bülteni, vol. 51, no. 3, 2020, pp. 168-70, doi:10.16948/zktipb.613162.
Vancouver Uygur Külcü N, Erdede Ö, Doğru M, Eraslan GE, Sarı E, Yıldız F. LAMOTRİGİNE BAĞLI OLASI DRESS SENDROMU: OLGU SUNUMU. Zeynep Kamil Tıp Bülteni. 2020;51(3):168-70.