Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular

Özlem Arslan Ünlütürk; Özlem Temel; Müjgan Oral; Serpil Değirmenci; Savaş İnan

doi:10.16948/zktb.51296

Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular

Year 2002, Volume: 33 Issue: 2, 44 - 47, 01.03.2002

Özlem Arslan Ünlütürk Özlem Temel Müjgan Oral Serpil Değirmenci Savaş İnan

Abstract

Henoch-Schönlein purpurası (HSP) nedeni kesin olarak bilinmeyen çeşitli antijenik uyarılarla meydana gelen immun komplekslerin yol açtığı kabul edilen bir hastalıktır. Daha çok belirgin cilt tutulumu ile seyreder, fakat visseral organlarda da benzer lezyonlar nedeni ile önemli sonuçlar doğurabilmektedir. Henoch-Schönlein purpuralı çocuklarda renal ve gastrointestinal sistem tutulumunu gösteren faktörleri araştırmak amacıyla yaş ortalaması 7.45 + 2.75 olan 72 çocuğu retrospektif olarak inceledik. Gastrointestinal sistem ve renal tutulum bulunan çocuklarda yaş ve IgA değerleri istatistiksel olarak anlamlı yüksek bulundu. Renal tutulum bulunanlarda hipertansiyon yüzdesi renal tutulum bulunmayanlardan anlamlı yüksek bulundu.

Keywords

Purpura, Schoenlein-Henoch, Antijen-antikor kompleksi, Geriyedönük çalışma, Hipertansiyon

References

1. Richard BJ: Immunity Allergy and Disease of Inflamation. In : Behrman RE ,Kliegman R, Nelson W, Vaughan V(ed) ,NelsonTextbook of Pediatrics :Saunders Company,1992:628- 629
2. Nephrology ,Oxford Medical Pub. 1992:595-612. Haycock GB :The nephritis of Henoch -Schönlein purpura, InCameron S ,DavidsonA ,GnmfeldJP Xerr D ,Ritz E(eds) ,Oxford Textbook of Clinical 3. Habib R,Niaudet P:Renal involvment in Schönlein-Henoch purpura ,In:Tisher CC, Brenner Bin (eds),Renal pathology with Clinical and Functional Correlations,Philadelphia :J:B Lippincot Company,,1989:409-420
4. Szer IS .Henoch-Schönlein Purpura:when and how to treat ? J Rhematol1996,23:161 -165
5. Tramontano G ,Pondrano M,Buanagura G,Climalio ML :Schönlein-Henoch Syndrome Clinico Istatistical analysis of 60 cases ,Pediatr Med Chir. 1985 ;142:563
6. Whang YJ ,Chi CS ,Shian WJ :Clinical studies of Henoch-Schönlein Purpura in Chene.se children ,Chung-Hua-l- Hsuein Tsa-Chih-Jajpel 1993;51:345
7. Hızarcıoğlu M,Betih NJlçi A,Bayındır N,Kayserili E .-Henoch- Schönlein vaskülitli 75 olgunun retrospektif değerlendiril me si,21-Ortadoğu ve Akdeniz Pediatri Dernekleri Birliği Kongresi,1993
8. Akpınar M Janyer G,Serdaroğlu A.Tunçbilek Henoch-Schönlein Sendromlu 47 çocuk hastada Epidemiyolojik ve Klinik Bir Çalışma,Ankara Hastanesi Dergisi 1989;24:41
9. Vaughen VC, Behrman RE:Nelson Textbook of Pediatrics Company 577-579,1338-1340
10. Zurowska AM ,Wrzolkowa T,Uszyeka-Karez M,Henoch -Schönlein nephritis in children -A Clinicopathological study .Int J Pediatri Nephrol 1985;6:183-188
11. Bagga A ,Kabra SK ,Srivasaya RN,Bhuyan VN. Henoch- Schönlein syndrome in northern Indian Children. Indian Pediatr 1991; 28:1153-1157
12. Balmelli C,Laux-End R ,D: Rocco D , Carvajal-Buslinger Ml,Bianchetti MG. Henoch-Schönlein purpura: course in 139 children. Schweiz Med wochenschr 1996, 126: 293-298
13. Fischer PJ, Hagga W, Hecker W: Schönlein-Henoch Purpura: A Clinical study of patient with special reference to unusual complication. Monotsschr Kindehelizd 1990; 138(37):128
14. Bana G, Monti G: Schönlein-Henoch Syndrome in children Clinico epidemiologic analysis of 170 cases, Minera Pediatrics, 1989;41(12);585
15. Wananukul S, Watana D, Pongprosit P. Henoch-Schönlein purpura Thailand: review of 41 children. J Med Assoc Thai 1997; 80; 686-692
16. Al Harbi NN. Henoch-Schönlein Syndrome in children: experience from southern part of Saudi Arabia.East Afr Med J 1996:73:191-193
17. Lin SJ, Chao HC, Huang JC. Gastrointestinal involvement as the initial manifestation in children with Henoch-Schönlein purpura - Clinical analysis of 27 cases. Chung Him M in Kua Hsiao Erh Ko I Hsueh Hui Tsa Chih 1999;39; 186-90
18. Tapson KMP Henoch-Schönlein purpura .Am J Fam Physician 1993:4:311-315
19. Clark JH ;Fitzgerald JF .Hemorrhagic complications of Henoch-Schönlein Syndrom. J Pediatr Gastroenteral Nutr 1985;4:311-315
20. Tomamasa T ,Hsu JY, Itah K et al.Endoscopik findings in pediatric patients with Henoch- Schönlein Purpura and gastrointestinal symptoms J Pediatrr Gastroenteral Nutr.1987 ;6.725-729
21. White RHR .Henoch-Schönlein Nephritis.Nephron 1994:68:1-9
22. Kraft DM .McKee D Scott C,Henoch-Schönlein Purpura : a review .Am Fam Physician 1998:58:405-408
23. Söylemezoğlu O, Sultan N, Gürsel T,Buyan N, Hasanoğlu E, circulation adhesion molecules ICAM-I,E-selection, and Von W illebr and factor in Henoch-Schönlein purpura. Arch Dis Child 1956:75-507-511
24. Kawana S,Otha M,Nishiyama S. Value of the assay for IgA containing circulating immun complexes in Dermatologica Henoch-Schönlein Purpura.Dermatologica 1986; 172:245-253
25. Kaku Y,Nohara K,Honda S.Renal involvementin Henoch- Schönlein purpura:amultivarite analysis * of prognostic factors.Kidney Int 1998;53':! 755-1759

Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular

Year 2002, Volume: 33 Issue: 2, 44 - 47, 01.03.2002

Özlem Arslan Ünlütürk Özlem Temel Müjgan Oral Serpil Değirmenci Savaş İnan

Abstract

Henoch-Schoenlein purpura is a disorder of which etiology is not cleary understood and considered as an immuncomplex disease. HSP is generally presented with skin lesions but also similar lesions may occur at visceral organs and cause serious complications. In order to evaluate risk factors assciated with renal and gastrointestinal involvement in children with Henoch-Schoenlein purpura, we evaluaeted 72 children, aged 7.45±2.75 years, retrospectively. In children with nephritis and gastrointestinal involvement, age and IgA level were significantly higher than valves in children without nephrit and gastrointestinal involvement. And also in children with HSP nephrits the percent of hypertension was significantly higher than valves in children without nephritis.

Keywords

Purpura, Schoenlein-Henoch, Antigen-Antibody Complex, Retrospective Studies, Hypertension

References

1. Richard BJ: Immunity Allergy and Disease of Inflamation. In : Behrman RE ,Kliegman R, Nelson W, Vaughan V(ed) ,NelsonTextbook of Pediatrics :Saunders Company,1992:628- 629
2. Nephrology ,Oxford Medical Pub. 1992:595-612. Haycock GB :The nephritis of Henoch -Schönlein purpura, InCameron S ,DavidsonA ,GnmfeldJP Xerr D ,Ritz E(eds) ,Oxford Textbook of Clinical 3. Habib R,Niaudet P:Renal involvment in Schönlein-Henoch purpura ,In:Tisher CC, Brenner Bin (eds),Renal pathology with Clinical and Functional Correlations,Philadelphia :J:B Lippincot Company,,1989:409-420
4. Szer IS .Henoch-Schönlein Purpura:when and how to treat ? J Rhematol1996,23:161 -165
5. Tramontano G ,Pondrano M,Buanagura G,Climalio ML :Schönlein-Henoch Syndrome Clinico Istatistical analysis of 60 cases ,Pediatr Med Chir. 1985 ;142:563
6. Whang YJ ,Chi CS ,Shian WJ :Clinical studies of Henoch-Schönlein Purpura in Chene.se children ,Chung-Hua-l- Hsuein Tsa-Chih-Jajpel 1993;51:345
7. Hızarcıoğlu M,Betih NJlçi A,Bayındır N,Kayserili E .-Henoch- Schönlein vaskülitli 75 olgunun retrospektif değerlendiril me si,21-Ortadoğu ve Akdeniz Pediatri Dernekleri Birliği Kongresi,1993
8. Akpınar M Janyer G,Serdaroğlu A.Tunçbilek Henoch-Schönlein Sendromlu 47 çocuk hastada Epidemiyolojik ve Klinik Bir Çalışma,Ankara Hastanesi Dergisi 1989;24:41
9. Vaughen VC, Behrman RE:Nelson Textbook of Pediatrics Company 577-579,1338-1340
10. Zurowska AM ,Wrzolkowa T,Uszyeka-Karez M,Henoch -Schönlein nephritis in children -A Clinicopathological study .Int J Pediatri Nephrol 1985;6:183-188
11. Bagga A ,Kabra SK ,Srivasaya RN,Bhuyan VN. Henoch- Schönlein syndrome in northern Indian Children. Indian Pediatr 1991; 28:1153-1157
12. Balmelli C,Laux-End R ,D: Rocco D , Carvajal-Buslinger Ml,Bianchetti MG. Henoch-Schönlein purpura: course in 139 children. Schweiz Med wochenschr 1996, 126: 293-298
13. Fischer PJ, Hagga W, Hecker W: Schönlein-Henoch Purpura: A Clinical study of patient with special reference to unusual complication. Monotsschr Kindehelizd 1990; 138(37):128
14. Bana G, Monti G: Schönlein-Henoch Syndrome in children Clinico epidemiologic analysis of 170 cases, Minera Pediatrics, 1989;41(12);585
15. Wananukul S, Watana D, Pongprosit P. Henoch-Schönlein purpura Thailand: review of 41 children. J Med Assoc Thai 1997; 80; 686-692
16. Al Harbi NN. Henoch-Schönlein Syndrome in children: experience from southern part of Saudi Arabia.East Afr Med J 1996:73:191-193
17. Lin SJ, Chao HC, Huang JC. Gastrointestinal involvement as the initial manifestation in children with Henoch-Schönlein purpura - Clinical analysis of 27 cases. Chung Him M in Kua Hsiao Erh Ko I Hsueh Hui Tsa Chih 1999;39; 186-90
18. Tapson KMP Henoch-Schönlein purpura .Am J Fam Physician 1993:4:311-315
19. Clark JH ;Fitzgerald JF .Hemorrhagic complications of Henoch-Schönlein Syndrom. J Pediatr Gastroenteral Nutr 1985;4:311-315
20. Tomamasa T ,Hsu JY, Itah K et al.Endoscopik findings in pediatric patients with Henoch- Schönlein Purpura and gastrointestinal symptoms J Pediatrr Gastroenteral Nutr.1987 ;6.725-729
21. White RHR .Henoch-Schönlein Nephritis.Nephron 1994:68:1-9
22. Kraft DM .McKee D Scott C,Henoch-Schönlein Purpura : a review .Am Fam Physician 1998:58:405-408
23. Söylemezoğlu O, Sultan N, Gürsel T,Buyan N, Hasanoğlu E, circulation adhesion molecules ICAM-I,E-selection, and Von W illebr and factor in Henoch-Schönlein purpura. Arch Dis Child 1956:75-507-511
24. Kawana S,Otha M,Nishiyama S. Value of the assay for IgA containing circulating immun complexes in Dermatologica Henoch-Schönlein Purpura.Dermatologica 1986; 172:245-253
25. Kaku Y,Nohara K,Honda S.Renal involvementin Henoch- Schönlein purpura:amultivarite analysis * of prognostic factors.Kidney Int 1998;53':! 755-1759

There are 24 citations in total.

Details

Primary Language	Turkish
Journal Section	Articles
Authors	Özlem Arslan Ünlütürk This is me Özlem Temel This is me Müjgan Oral This is me Serpil Değirmenci This is me Savaş İnan This is me
Publication Date	March 1, 2002
Published in Issue	Year 2002 Volume: 33 Issue: 2

Cite

APA	Ünlütürk, Ö. A., Temel, Ö., Oral, M., Değirmenci, S., et al. (2002). Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular. Zeynep Kamil Tıp Bülteni, 33(2), 44-47. https://doi.org/10.16948/zktb.51296
AMA	Ünlütürk ÖA, Temel Ö, Oral M, Değirmenci S, İnan S. Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular. Zeynep Kamil Tıp Bülteni. March 2002;33(2):44-47. doi:10.16948/zktb.51296
Chicago	Ünlütürk, Özlem Arslan, Özlem Temel, Müjgan Oral, Serpil Değirmenci, and Savaş İnan. “Henoch-Schönlein Purpuralı Hastalarda Renal Ve Gastrointestinal Sistem Tutulumla ilişkili Klinik Ve Laboratuar Bulgular”. Zeynep Kamil Tıp Bülteni 33, no. 2 (March 2002): 44-47. https://doi.org/10.16948/zktb.51296.
EndNote	Ünlütürk ÖA, Temel Ö, Oral M, Değirmenci S, İnan S (March 1, 2002) Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular. Zeynep Kamil Tıp Bülteni 33 2 44–47.
IEEE	Ö. A. Ünlütürk, Ö. Temel, M. Oral, S. Değirmenci, and S. İnan, “Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular”, Zeynep Kamil Tıp Bülteni, vol. 33, no. 2, pp. 44–47, 2002, doi: 10.16948/zktb.51296.
ISNAD	Ünlütürk, Özlem Arslan et al. “Henoch-Schönlein Purpuralı Hastalarda Renal Ve Gastrointestinal Sistem Tutulumla ilişkili Klinik Ve Laboratuar Bulgular”. Zeynep Kamil Tıp Bülteni 33/2 (March 2002), 44-47. https://doi.org/10.16948/zktb.51296.
JAMA	Ünlütürk ÖA, Temel Ö, Oral M, Değirmenci S, İnan S. Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular. Zeynep Kamil Tıp Bülteni. 2002;33:44–47.
MLA	Ünlütürk, Özlem Arslan et al. “Henoch-Schönlein Purpuralı Hastalarda Renal Ve Gastrointestinal Sistem Tutulumla ilişkili Klinik Ve Laboratuar Bulgular”. Zeynep Kamil Tıp Bülteni, vol. 33, no. 2, 2002, pp. 44-47, doi:10.16948/zktb.51296.
Vancouver	Ünlütürk ÖA, Temel Ö, Oral M, Değirmenci S, İnan S. Henoch-Schönlein purpuralı hastalarda renal ve gastrointestinal sistem tutulumla ilişkili klinik ve laboratuar bulgular. Zeynep Kamil Tıp Bülteni. 2002;33(2):44-7.