The changes of the ovarian function after ectopic pregnancy treatment (laparoscopic salpingostomy and systemic methotrexate)

Year 2007, Volume: 38 Issue: 4, 143 - 150, 01.05.2007

Namık Kemal Duru Murat Muhcu İbrahim Alanbay Uğur Keskin Vedat Atay

Abstract

The Changes of The Ovarian Function after Ectopic Pregnancy Treatment (Laparoscopic salpingostomy and systemic Methotrexate) Aim: To evaluate the changes of the ovarian function inpatients with ectopic pregnancy treated by laparoscopic salpingostomy and systemic single dose methotreaxate. Materials and Methods: This study was included 28 patients with ectopic pregnancy treated by laparoscopic salpingostomy and 14 patients with ectopic pregnancy treated by 50 mg/m2 single dose methotrexate, from January 2005 to July 2007. All patients were evaluated by transvaginal sonography before treatment to determine both ovarian volumes, antral follicle counts and bloodflow characteristics. SPSS for Windows 13.0 was used for statistical analysis. Results: The mean age was 30.6±4.5 in patients treated by laparoscopy, whereas it was 30.07±3.6 in patients treated by methotrexate (p: 0,68). Gravidity and partity were 0,92±1,11 and 0,50 ± 0,63 in patients treated by laparoscopy, whereas they were 0,78 ±0,8 and 0,5 ±0,65 in patients treated by methotrexate respectively. Conclusion: Our results showed that both treatment modalities (laparoscopic salpingostomy and systemic methotreaxate) have no adverse effect on the ovarianfunction.

Keywords

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Ektopik gebelik sonrası (laparoskopik salpingostomi ve sistemik methotrexate) ovarian fonksiyonlardaki değişim

Abstract

Amaç: Laparoskopik salpingostomi ve sistemik tek doz Methotrexate uygulanan hastalarda ovarian fonksiyonlardaki değişimi incelemektir. Gereç ve Yöntem: Bu çalışma Ocak 2005-Temmuz 2007 tarihleri arasında, Ektopikgebelik tanısı ile laparoskopik salpingostomi uygulanan 28 hasta ve 50 mg/m2 tek doz Methotrexate uygulanan 14 hasta dayapılmıştır. Tüm hastalara tedavi öncesi her iki overe ait volüm, antral follikül sayısı ve akım paternlerini değerlendirmek için transvajinal ultrasonografi uygulandı. İstatistiksel analiz için, SPSS for Windows 13.0 paket programı kullanıldı. Bulgular: Laparoskopik salpingostomi uygulanan grupta ortalama yaş 30,6 (-/+ 4,5) iken, Methotrexate uygulanan grupta ise 30,07 (-/+ 3,6) idi (p: 0,68). Hastaların gravida ve pariteleri değerlendirildiğinde sırası ile laparoskopik salpingostomi uygulanan grupta 0,92 (-/+ 1,11), 0,50 (-/+ 0,63) iken; Methotrexate uygulanan grupta ise 0,78 (-/+ 0,8), 0,5 (-/+ 0,65) idi. Sonuç: Elde edilen veriler uygulanan tedavi modalitelerinin (laparoskopik salpingostomi ve sistemik Methotrexate kullanımı) ovarian fonksiyonlar üzerinde olumsuz etkilerinin olmadığını göstermektedir.

Keywords

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