Year 2019, Volume 9, Issue 2, Pages 183 - 190 2019-06-30

Normal Placental Development and the Triad of Placental Dysfunction: The Maternal and Fetal Complications
Normal Plasental Gelişim ve Plasental Disfonksiyon Triadı: Maternal ve Fetal Komplikasyonlar

Arielle Hough [1] , Sathees B Chandra [2]

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The placenta is crucial to the development of a fetus, playing a vital role from fertilization of an egg by sperm until the delivery of the fetus. Without the placenta, the fetus would not receive essential nutrients or oxygen from the mother and be able to rid itself of toxic wastes. Given the necessity of this temporary organ, improper formation of the placenta can lead to many health problems. These complications have an effect on the mother as well as the fetus given the essential link the placenta makes between fetal and maternal circulation. The main concerns with impaired placental function are commonly known as the triad of placental dysfunction. The triad of placental dysfunction includes preeclampsia, HELLP Syndrome, and IUGR (Intrauterine Growth Restriction) . The purpose of this review article is to explore the pathogenesis, the diagnostic and predictive criteria, and treatment for the disorders composing the triad of placental dysfunction to allow better outcomes for both the mother and fetus.

Bir yumurtanın sperm tarafından döllenmesinden, fetüsün doğuşuna kadar önemli bir rol oynayan plasenta,  fetüsün gelişimi için çok önemlidir. Plasenta olmadan, fetus anneden gerekli besinleri ya da oksijeni alamaz ve toksik atıklardan kurtulamaz. Bu geçici organın gerekliliği göz önüne alındığında, plasentanın yanlış oluşması birçok sağlık sorununa neden olabilir. Fetal ve maternal dolaşım arasında yaptığı temel bağlantı nedeniyle plasentada oluşacak bu komplikasyonların fetusun yanı sıra anne üzerinde de etkisi vardır. Bozulmuş plasental fonksiyon ile ilgili ana endişeler, yaygın olarak, plasental disfonksiyonun üçlüsü olarak bilinir. Plasental disfonksiyon üçlüsünde preeklampsi, HELLP Sendromu ve IUBG (İntrauterin Büyüme Geriliği) bulunur. Bu derlemenin amacı hem anne hem de fetüs için daha iyi sonuçlara erişmek amacıyla plasental disfonksiyon üçlüsünü oluşturan hastalıkların patogenezini, tanı ve öngörü kriterlerini ve tedavisini araştırmaktır.

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Primary Language en
Journal Section Review
Authors

Orcid: 0000-0002-5685-8722
Author: Arielle Hough
Institution: Biomedical Sciences Program, College of Nursing and Health Sciences, Barry University
Country: United States


Orcid: 0000-0002-0702-8925
Author: Sathees B Chandra (Primary Author)
Institution: Biomedical Sciences Program, College of Nursing and Health Sciences, Barry University
Country: United States


Dates

Publication Date: June 30, 2019

EndNote %0 Journal of Contemporary Medicine Normal Placental Development and the Triad of Placental Dysfunction: The Maternal and Fetal Complications %A Arielle Hough , Sathees B Chandra %T Normal Placental Development and the Triad of Placental Dysfunction: The Maternal and Fetal Complications %D 2019 %J Journal of Contemporary Medicine %P -2667-7180 %V 9 %N 2 %R doi: 10.16899/jcm.562662 %U 10.16899/jcm.562662