Year 2014, Volume 15, Issue 2, Pages 207 - 217 2014-08-01

Diabetik Retinopati ve Etiyopatogenezi
Diabetik Retinopati ve Etiyopatogenezi

Sibel İNAN [1]

236 450

Chronic hyperglycemia is one of the most important factors for the formation and progression of diabetic retinopathy (DR). Insulin resistance and hyperinsulinemia, altered fatty acid and protein metabolism, osmotic effect, hypertension, impaired metabolic sympathetic activation are other important risk factors. Oxidative stress also increases in diabetes, but exact contribution of related mechanisms to diabetic complications has not been fully verified. Platelet derived growth factor (PDGF) that take place in the pathogenesis of DR together with vascular endothelial growth factor (VEGF) produces angiogenesis in microvascular structures by stimulating migration and proliferation of RPE and glial cells
Kronik hiperglisemi, diyabetik retinopati (DR) oluşumu ve ilerlemesinde en önemli etkenlerden biridir. Diğer risk faktörleri içinde; insülin direnci ve hiperinsülinemi, değişmiş olan yağ asidi ve protein metabolizması, ozmotik etki, hipertansiyon, bozulmuş metabolik sempatik aktivasyon sayılabilir. Diyabette oksidatif stres de artabilmektedir, ancak ilgili mekanizmaların diabetik komplikasyonlara katkısı tam olarak ispatlanmış değildir. Vasküler endotelyal büyüme faktörü (VEGF) ile birlikte DR patogenezinde rol oynayan platelet kaynaklı büyüme faktörü (PDGF), retina pigment epitel hücresi ve glial hücre göçü ve proliferasyonunu uyararak mikrovasküler yapıda anjiogenezis yapar
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Author: Sibel İNAN

Bibtex @ { kocatepetip182225, journal = {Kocatepe Tıp Dergisi}, issn = {1302-4612}, eissn = {2149-7869}, address = {Afyonkarahisar Sağlık Bilimleri Üniversitesi}, year = {2014}, volume = {15}, pages = {207 - 217}, doi = {10.18229/ktd.56779}, title = {Diabetik Retinopati ve Etiyopatogenezi}, key = {cite}, author = {İNAN, Sibel} }
APA İNAN, S . (2014). Diabetik Retinopati ve Etiyopatogenezi. Kocatepe Tıp Dergisi, 15 (2), 207-217. Retrieved from http://dergipark.org.tr/kocatepetip/issue/17402/182225
MLA İNAN, S . "Diabetik Retinopati ve Etiyopatogenezi". Kocatepe Tıp Dergisi 15 (2014): 207-217 <http://dergipark.org.tr/kocatepetip/issue/17402/182225>
Chicago İNAN, S . "Diabetik Retinopati ve Etiyopatogenezi". Kocatepe Tıp Dergisi 15 (2014): 207-217
RIS TY - JOUR T1 - Diabetik Retinopati ve Etiyopatogenezi AU - Sibel İNAN Y1 - 2014 PY - 2014 N1 - DO - T2 - Kocatepe Tıp Dergisi JF - Journal JO - JOR SP - 207 EP - 217 VL - 15 IS - 2 SN - 1302-4612-2149-7869 M3 - UR - Y2 - 2019 ER -
EndNote %0 Kocatepe Medical Journal Diabetik Retinopati ve Etiyopatogenezi %A Sibel İNAN %T Diabetik Retinopati ve Etiyopatogenezi %D 2014 %J Kocatepe Tıp Dergisi %P 1302-4612-2149-7869 %V 15 %N 2 %R %U
ISNAD İNAN, Sibel . "Diabetik Retinopati ve Etiyopatogenezi". Kocatepe Tıp Dergisi 15 / 2 (August 2014): 207-217.