Necrotizing Fasciit Associated with Naltrexone Implant- First Case Report

Abstract

Necrotizing fasciit (NF) is an infrequent, life- threatening bacterial infection characterized by quickly progressive inflammation and necrosis of the skin, subcutaneous tissue and superficial fascia. Even though there are many defined ethiolojical factors that can predispose patients to NF, there is limited information on literature about the cases with NF that assosiated naltrexone implants. So, we

presented a 26 year old, opioid dependent male patient with NF after a treatment by means of naltexone implant for 3 times.

Keywords

• Necrotizing fasciit,naltrexone implant,surgical debridement

Naltrekson İmplantına Bağlı Gelişen Nekrotizan Fasiit- İlk Olgu Sunumu

Öz

Nekrotizan fasiit (NF) cilt, cilt altı dokular ve yüzeyel fasyanın hızlı ilerleyen enflamasyon ve nekrozu ile karakterize, nadir görülen ve hayatı tehdit eden bakteriyel bir enfeksiyondur. NF’e neden olan çok sayıda tanımlanmış etyolojik faktör olmasına rağmen, literatürde Naltrekson implantları ile ilişkili NF hakkında kısıtlı bilgi mevcuttur.

Biz de üç kez Naltrekson implantı uygulanan 26 yaşındaki opioid bağımlısı, erkek NF vakasını literatür eşliğinde sunmayı amaçladık.

Anahtar Kelimeler

• Nekrotizan fasiit,Naltrekson implantı,cerrahi debridman

Kaynakça

1. 1. Trent JT, Kirsner RS, Diagnosing nectotizing fasciitis. Adv Skin Wound Care 2002; 15(3):135-8.
2. 2. Schroeder JL, Steinke EE, Necrotizing fasciitis-the importence of early diagnoses and debridement, AORN J 2005; 82(6):1031-40.
3. 3. Khamnuan P, Chonqruksut W, Jearwattanakanok K, Patumanond J, Yodluangfun S, Tantraworasin A, Necrotizing Fasciitis: Risk Factors of Mortality. Risk Manag Healthc Policy. 2015; 8: 1-7.
4. 4. Salcido RS, Necrotizing Fasciitis: Reviewing the Causes and Treatment Strategies. Adv Skin Wound Care 2007;20:288-93; quiz 294-5.
5. 5. Kuncir EJ, Tillou A,Hill CR, Pitrone P, Kimbrell B, Asencio JA: Necrotizing soft tissue infections, Emerg Med Clin North Am 2003; 21: 1075-87.
6. 6. Özgönül A, Yazar S, Nekrotizan Fasiyit: 18 Hasta ile konunun irdelenmesi.Tıp Araştırmaları Dergisi 2007;5(3):111-114.
7. 7. Wong CH, Chang HC, Pasupathy S,Khin LW, Tan JL, Low CO. Necrotizing Fasciitis: Clinical Presentation, Microbiology and Determinants of Mortality. J Bone JOİNT Surg Am 2003;85-A:1454-60.
8. 8. Clayton MD, Flowler JE Jr, Sharili R et al:Causes , presentation and survival of fifty-seven patients with necrotizing fasciitis of the male genitalia, Surg Gynecol Obstet 1990;170:49-5.

9. 9. Kaul R, McGeer A, Low DE et al: Popoulation-based surveillance for group A streptococcal necrotizing fasciitis: clinical features, prognostic indicators, and microbiologic analysis of seventy-seven cases. Ontario grup A streptococcal study, Am J Med 1997; 103:18-24.
10. 10. Faucher LD, Morris SE, Edelman LS, Saffle JR: Burn center management of necrotizing soft tissue surgical infections in unburned patients, Am J Surg 2001; 182: 563-9.