The relationship between phase angle, nutritional status and blood biochemical parameters in hemodialysis patients: an example study in Edirne city center

Year 2025, Volume: 7 Issue: 2, 210 - 217, 21.03.2025

Merve Pehlivan , Esra Karateke , Ebrar Çalışkan

https://doi.org/10.38053/acmj.1637989

Abstract

Aims: Phase angle (PA) is recommended as a noninvasive and objective index to make an assessment of hemodialysis patients’ nutritional conditions. This study aimed to investigate the relationship of PA with nutritional status and blood biochemical parameters in patients on hemodialysis.
Methods: A descriptive and cross-sectional research design was employed. The study was conducted with 100 hemodialysis patients (mean±SD: 62.79±11.73 years) between February and July 2024. Data collection tools included a questionnaire about patients’ descriptive characteristics, a 24-hour food record form, the Global Leadership Initiative on Malnutrition (GLIM) criteria, the Malnutrition Universal Screening Tool (MUST), the 7-point Subjective Global Assessment (7p-SGA) scale, and the Nutritional Risk Screening-2002 (NRS-2002) scale.
Results: Patients with or at risk of malnutrition, identified using GLIM, MUST, and 7p-SGA criteria, had significantly lower mean PA, than patients without malnutrition risk (p=0.001, p=0.008, p=0.004, respectively). According to NRS-2002 criteria, participants who were at risk of malnutrition and needed starting a nutrition plan had significantly lower mean PA than those requiring weekly NRS-2002 assessments (p=0.017). The association of PA with lean body-mass (r=0.257, p=0.010), muscle mass
(r=0.264, p=0.008), TSF thickness (r=0.259, p=0.009) and albumin (r=0.313, p=0.002) was positive, weak or very weak, and statistically meaningful.
Conclusion: Hemodialysis patients with or at risk of malnutrition had lower PA values according to various assessment tools. This suggests that PA may function as a possible indicator for identifying nutritional deficiencies in hemodialysis patients without delay.

Keywords

Phase angle, nutritional status, biochemical parameters

Ethical Statement

This study was conducted in accordance with the Declaration of Helsinki, and the approval of the Ethics Committee of Trakya University Faculty of Medicine was obtained to conduct the research (protocol no: TUTF-GOBAEK 2023/441, decision number:17/37, date: 13 November 2023).

Supporting Institution

This study was supported by the TUBITAK 2209-A University Student Research Projects Support Program with the project number 1919B012334935.

Project Number

1919B012334935

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