Malignant Fibrous Histiocytoma

Yıl 1996, Cilt: 1 Sayı: 2, 46 - 48, 30.12.1996

Sevgiye Kaçar Özkara Cengiz Erçin Bahar Müezzinoğlu Neşet Nuri Gönüllü Bekir Eraldemir Tuncer Öcalan

Öz

Malignant fibrous histiocytoma is the
mostly encountered soft tissue sarcoma around the seventh decade of life.
Usually, it is located at lower ekstremities and deep in the muscles. It is
seen in 4 histopathological subtypes, namely storiform pleomorphic, myxoid, giant
cell and inflammatory types respectively. At this presentation, there are two
malignant fibrous histiocytoma cases, one of storiform-pleomorphic and the
other of giant cell types; the first located at the axillary region and the
second located at the upper extremity subcutaneously. The first patient is 67
years of age and the second one is 71, both being males.

Anahtar Kelimeler

Malignant fibrous histiocytoma (MFH), storiform-pleomorphic, giant cell

Malign Fibröz Histiositom

Öz

Malign fibröz histiositom, yedinci
dekad civarında en sıklıkla görülen yumuşak doku sarkomudur. Genellikle alt
ekstremitelerde ve kas içerisinde derin yerleşimli olan bu tümor, 4
histopatolojik tipte görülür. (Görülme sıklığına göre, storiform-pleomorfik,
mikzoid, dev hücreli ve inflamatuvar tipler.) Bu sunumda biri aksilla, diğeri
ise üst ekstremitede subkutan yerleşimli, ilki storiform-pleomorfik, ikincisi
ise dev hücreli tipte iki malign fibröz histiositom olgusu yer almaktadır. Hastalardan
ilki 67, ikincisi ise 71 yaşında olup, her ikisi de erkektir.

Anahtar Kelimeler

Malign fibröz histiositom (MFH), storiform-pleomorfik, dev hücreli

Kaynakça

• Enzinger FM, Weis SW. Soft Tissue Tumors. 3rd Edition. St. Louis: Mosby-Year Book Inc; 1995:351-380.
• Rosai J. Ackerman's Surgical Pathology ,8th Edition(Vol2). St. Louis: Mosby-Year Book Inc; 1996:2036-2041.
• Cotran RS, Kumar V, Robbins SL. In: Schoen FJ, ed. Pathologic Basis of Disease. 5th Edition. Philadelphia: W.B. Saunders; 1994:1267.
• Hollowood K, Fletcher CD. Malignant fibrous histiocytoma:morphologic pattern or pathologic entity? Semin Diagn Pathol. 1995;12(3):210-220.
• Takeya M, Yamasiro S, Yoshimura T, Takahashi K. lmmunophenotypic and immunoelectron microscopic charaterzation of major constituent cells in malignant fibrous histiocytoma using human cell lines and their transplanted tumors in immunodeficient mice. Lab Invest. 1995;72(6):679-688.
• Menztel T, Fletcher CD. Malignant mesenchymomas of soft tissue associated with numerous osteoclast-like giant cells mimicking the so called giant celt variant of "malignant fibrous histioscytoma" Virchows Arch. 1994;424(5):539-545. doi:10.1007/bf00191441