Olgu Sunumu
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Gardner Sendromu: Olgu Sunumu

Yıl 1997, Cilt: 2 Sayı: 2, 45 - 47, 30.04.1997

Öz

Ailesel adenomatöz polipozis koli sendromları; kolonda yüzlerce-binlerce adenomatöz poliple karakterize, nadir görülen, otozomal dominant geçişli sendromlardır. Gardner sendromundaki ekstraintestinal bulgular; osteomalar, yumuşak doku tümörleri, tiroid ve adrenal tümörleri ve retinal pigment epitel hipertrofisidir. Tedavi cerrahidir.

Kaynakça

  • Burt RW, Bishop DT, Lynch HT, Rozen P, Winawer SJ. Risk and surveillance of individuals with heritable factors for colorectal cancer. WHO Collaborating Centre for the Prevention of Colorectal Cancer. Bull World Health Organ. 1990;68(5):655-665.
  • Pathak S, Hopwood VL, Hughes JI, Jackson GL. Identification of colon cancer-predisposed individuals: a cytogenetic analysis. Am J Gastroenterol. 1991;86(6):679-684.
  • Tonelli F, Nardi F, Bechi P, Taddei G, Gozzo P, Romagnoli P. Extracolonic polyps in familial polyposis coli and Gardner's syndrome. Dis Colon Rectum. 1985;28(9):664-668. doi: 10.1007/bf02553447
  • Nannery WM, Barone JG, Abouchedid C. Familial polyposis coli & Gardner's syndrome. N J Med. 1990 ;87(9):731-733.
  • Bridge JA, Sreekantaiah C, Mouron B, Neff JR, Sandberg AA, Wolman SR. Clonal chromosomal abnormalities in desmoid tumors. Implications for histopathogenesis. Cancer. 1992;69(2):430-436. doi:10.1002/1097-0142(19920115)69:2<430::aid-cncr2820690226>3.0.co;2-h
  • Salvi G, Menucci R, Scrivanti M, Valanzano R. [Hypertrophy of the pigment epithelium in familial intestinal polyposis]. Ophtalmologie. 1990;4(3):246-248.
  • Davies DR, Armstrong JG, Thakker N, et al. Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene. Am J Hum Genet. 1995;57(5):1151-1158.
  • Bell B, Mazzaferri EL. Familial adenomatous polyposis (Gardner's syndrome) and thyroid carcinoma. A case report and review of the literature. Dig Dis Sci. 1993;38(1):185-190. doi:10.1007/bf01296795
  • Naylor EW, Gardner EJ. Adrenal adenomas in a patient with Gardner's syndrome. Clin Genet. 1981;20(1):67-73. doi:10.1111/j.1399-0004.1981.tb01810.x
  • Zeze F, Ohsato K, Mitani H, Ohkuma R, Koide O. Hepatocellular carcinoma associated with familial polyposis of the colon. Report of case. Dis Colon Rectum. 1983;26(7):465-468. doi: 10.1007/bf02556528
  • Danes BS, Deschner EE. Detection of in vitro tetraploidy in heritable colon cancer syndromes. Confirmation by three different assays. Cancer. 1984;54(7):1353-1359. doi:10.1002/1097-0142(19841001)54:7<1353::aid-cncr2820540720>3.0.co;2-7
  • Heim S. In vitro growth characteristics of skin fibroblasts from patients with adenomatosis of the colon and rectum and their relatives. Clin Genet. 1983;23(1):41-48. doi:10.1111/j.1399-0004.1983.tb00436.x
  • Sams JS, Lynch HT, Burt RW, Boland CR. Abnormlities in lectin binding profiles in familial colon cancer and familial polyposis coli. Gastroenterology. 1985;88:1568.
  • Heim S, Johansen SG, Kolnig AM, Strömbeck B. Increased levels of spontaneous and mutagen-induced chromosome aberrations in skin fibroblasts from patients with adenomatosis of the colon and rectum. Cancer Genet Cytogenet. 1985;17(4):333-346. doi:10.1016/0165-4608(85)90117-7
  • Ponz de Leon M, Sassatelli R, Zanghieri G, et al. Hereditary adenomatosis of the colon and rectum: clinical features of eight families from northern Italy. Am J Gastroenterol. 1989;84(8):906-916.

Gardner Syndrome: Case Report

Yıl 1997, Cilt: 2 Sayı: 2, 45 - 47, 30.04.1997

Öz

Familial Adenomatous Polyposis Coli (FAPC) Syndromes are rare dominantly inherited syndromes characterized by hundreds to thousands of colonic adenomatous polyps. Extraintestinal abnormalities of Gardner syndrome are osteomas, soft tissue tumors, thyroid and adrenal tumors, hypertrophy of the retinal pigment epithelium. Management of FAPC is surgery

Kaynakça

  • Burt RW, Bishop DT, Lynch HT, Rozen P, Winawer SJ. Risk and surveillance of individuals with heritable factors for colorectal cancer. WHO Collaborating Centre for the Prevention of Colorectal Cancer. Bull World Health Organ. 1990;68(5):655-665.
  • Pathak S, Hopwood VL, Hughes JI, Jackson GL. Identification of colon cancer-predisposed individuals: a cytogenetic analysis. Am J Gastroenterol. 1991;86(6):679-684.
  • Tonelli F, Nardi F, Bechi P, Taddei G, Gozzo P, Romagnoli P. Extracolonic polyps in familial polyposis coli and Gardner's syndrome. Dis Colon Rectum. 1985;28(9):664-668. doi: 10.1007/bf02553447
  • Nannery WM, Barone JG, Abouchedid C. Familial polyposis coli & Gardner's syndrome. N J Med. 1990 ;87(9):731-733.
  • Bridge JA, Sreekantaiah C, Mouron B, Neff JR, Sandberg AA, Wolman SR. Clonal chromosomal abnormalities in desmoid tumors. Implications for histopathogenesis. Cancer. 1992;69(2):430-436. doi:10.1002/1097-0142(19920115)69:2<430::aid-cncr2820690226>3.0.co;2-h
  • Salvi G, Menucci R, Scrivanti M, Valanzano R. [Hypertrophy of the pigment epithelium in familial intestinal polyposis]. Ophtalmologie. 1990;4(3):246-248.
  • Davies DR, Armstrong JG, Thakker N, et al. Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene. Am J Hum Genet. 1995;57(5):1151-1158.
  • Bell B, Mazzaferri EL. Familial adenomatous polyposis (Gardner's syndrome) and thyroid carcinoma. A case report and review of the literature. Dig Dis Sci. 1993;38(1):185-190. doi:10.1007/bf01296795
  • Naylor EW, Gardner EJ. Adrenal adenomas in a patient with Gardner's syndrome. Clin Genet. 1981;20(1):67-73. doi:10.1111/j.1399-0004.1981.tb01810.x
  • Zeze F, Ohsato K, Mitani H, Ohkuma R, Koide O. Hepatocellular carcinoma associated with familial polyposis of the colon. Report of case. Dis Colon Rectum. 1983;26(7):465-468. doi: 10.1007/bf02556528
  • Danes BS, Deschner EE. Detection of in vitro tetraploidy in heritable colon cancer syndromes. Confirmation by three different assays. Cancer. 1984;54(7):1353-1359. doi:10.1002/1097-0142(19841001)54:7<1353::aid-cncr2820540720>3.0.co;2-7
  • Heim S. In vitro growth characteristics of skin fibroblasts from patients with adenomatosis of the colon and rectum and their relatives. Clin Genet. 1983;23(1):41-48. doi:10.1111/j.1399-0004.1983.tb00436.x
  • Sams JS, Lynch HT, Burt RW, Boland CR. Abnormlities in lectin binding profiles in familial colon cancer and familial polyposis coli. Gastroenterology. 1985;88:1568.
  • Heim S, Johansen SG, Kolnig AM, Strömbeck B. Increased levels of spontaneous and mutagen-induced chromosome aberrations in skin fibroblasts from patients with adenomatosis of the colon and rectum. Cancer Genet Cytogenet. 1985;17(4):333-346. doi:10.1016/0165-4608(85)90117-7
  • Ponz de Leon M, Sassatelli R, Zanghieri G, et al. Hereditary adenomatosis of the colon and rectum: clinical features of eight families from northern Italy. Am J Gastroenterol. 1989;84(8):906-916.
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Gastroenteroloji ve Hepatoloji
Bölüm Olgu Sunumu
Yazarlar

Altay Çelebi Bu kişi benim

Ömer Şentürk Bu kişi benim

Dilek Bayramgürler Bu kişi benim

Ergun Velidedeoğlu Bu kişi benim

Hülya Dal Bu kişi benim

Saadettin Hülagü Bu kişi benim

Yayımlanma Tarihi 30 Nisan 1997
Gönderilme Tarihi 12 Ocak 1997
Yayımlandığı Sayı Yıl 1997 Cilt: 2 Sayı: 2

Kaynak Göster

AMA Çelebi A, Şentürk Ö, Bayramgürler D, Velidedeoğlu E, Dal H, Hülagü S. Gardner Sendromu: Olgu Sunumu. Acta Med Nicomedia. Nisan 1997;2(2):45-47.

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