Primary hemangiomas are benign tumors that are very rare in the female genital tract and generally show an asymptomatic course.
CASE REPORT
A 44-year-old asymptomatic patient with a high ca125 level, transvaginal ultrasonography showed an irregular heterogeneous structure of 68 mm in size and fluid in the douglas pouch in the right ovary and right unilateral salpingooferectomy was performed. Morphologically tumoral lesion consisted of small, partially cuboid and depressed endothelial cells and proliferated vascular structures. As a result of supportive immunohistochemical studies, the case was diagnosed as "Ovarian Capillary Hemangioma".
DISCUSSION
We presented a rare case of ovarian capillary hemangioma, which was detected incidentally while being screened due to the high level of Ca 125 and we reviewed the histopathological features and differential diagnosis of this rare tumor in the light of the literature.
Mirilas, P., Georgiou, G., & Zevgolis, G. (1999). Ovarian cavernous hemangioma in an 8-year-old girl. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 9(2), 116–118. https://doi.org/10.1055/s-2008-1072225
Rodriguez M. A. (1979). Hemangioma of the ovary in an 81-year-old woman. Southern medical journal, 72(4), 503–504. https://doi.org/10.1097/00007611-197904000-00041
Akbulut, M., Bir, F., Colakoğlu, N., Soysal, M. E., & Düzcan, S. E. (2008). Ovarian hemangioma occurring synchronously with serous papillary carcinoma of the ovary and benign endometrial polyp. Annals of Saudi medicine, 28(2), 128–131. https://doi.org/10.5144/0256-4947.2008.1284.
Talerman A. (1967). Hemangiomas of the ovary and the uterine cervix. Obstetrics and gynecology, 30(1), 108–113.
Gehrig, P. A., Fowler, W. C., Jr, & Lininger, R. A. (2000). Ovarian capillary hemangioma presenting as an adnexal mass with massive ascites and elevated CA-125. Gynecologic oncology, 76(1), 130–132. https://doi.org/10.1006/gyno.1999.5648
Alvarez, M., & Cerezo, L. (1986). Ovarian cavernous hemangioma. Archives of pathology & laboratory medicine, 110(1), 77–78.
Kurman, R. J., Ellenson, L. H., & Ronnett, B. M. (2019). Nonspesific Tumors of the Ovary, Including Mesenchymal Tumors. In Blaustein's pathology of the female genital tract (pp. 1133–1134). essay, Springer. ISSBN 078-3-319-46334-6
Ziari, K., & Alizadeh, K. (2016). Ovarian Hemangioma: a Rare Case Report and Review of the Literature. Iranian journal of pathology, 11(1), 61–65.
DiOrio, J., Jr, & Lowe, L. C. (1980). Hemangioma of the ovary in pregnancy: a case report. The Journal of reproductive medicine, 24(5), 232–234.
Kaneta, Y., Nishino, R., Asaoka, K., Toyoshima, K., Ito, K., & Kitai, H. (2003). Ovarian
hemangioma presenting as pseudo-Meigs' syndrome with elevated CA125. The journal of obstetrics and gynaecology research, 29(3), 132–135. https://doi.org/10.1046/j.1341-8076.2003.00088.x
PRİMER UNİLATERAL OVERYAN KAPİLLER HEMANJİOM: OLGU SUNUMU
GİRİŞ
Primer hemanjiomlar, kadın genital traktında oldukça seyrek görülen, genellikle asemptomatik seyir
gösteren benign tümörlerdir.
OLGU SUNUMU
44 yaşında asemptomatik hastada, Ca125 düzeyinin yüksek gelmesi üzerine yapılan transvajinal ultrasonografisinde sağ overinde 68 mm boyutlarında düzensiz heterojen yapı ve douglas poşunda sıvı görülmüş ve sağ unilateral salpingooferektomi yapılmıştır. Morfolojik olarak; genel olarak küçük, bir kısmı küboidal ve basıklaşmış endotelyal hücreler ile döşeli prolifere vasküler yapılardan oluşan tümöral lezyon destekleyici immünhistokimyasal çalışmalar sonucunda “Overyan Kapiller Hemanjiom” tanısı almıştır.
TARTIŞMA
Biz burada; Ca 125 düzeyinin yüksekliği nedeniyle taranırken insidental olarak saptanan ve nadir bir antite olan overyan kapiller hemanjiom olgusunu sunup bu nadir tümörün histopatolojik özelliklerini ve ayırıcı tanısını literatür eşliğinde gözden geçirdik.
Mirilas, P., Georgiou, G., & Zevgolis, G. (1999). Ovarian cavernous hemangioma in an 8-year-old girl. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 9(2), 116–118. https://doi.org/10.1055/s-2008-1072225
Rodriguez M. A. (1979). Hemangioma of the ovary in an 81-year-old woman. Southern medical journal, 72(4), 503–504. https://doi.org/10.1097/00007611-197904000-00041
Akbulut, M., Bir, F., Colakoğlu, N., Soysal, M. E., & Düzcan, S. E. (2008). Ovarian hemangioma occurring synchronously with serous papillary carcinoma of the ovary and benign endometrial polyp. Annals of Saudi medicine, 28(2), 128–131. https://doi.org/10.5144/0256-4947.2008.1284.
Talerman A. (1967). Hemangiomas of the ovary and the uterine cervix. Obstetrics and gynecology, 30(1), 108–113.
Gehrig, P. A., Fowler, W. C., Jr, & Lininger, R. A. (2000). Ovarian capillary hemangioma presenting as an adnexal mass with massive ascites and elevated CA-125. Gynecologic oncology, 76(1), 130–132. https://doi.org/10.1006/gyno.1999.5648
Alvarez, M., & Cerezo, L. (1986). Ovarian cavernous hemangioma. Archives of pathology & laboratory medicine, 110(1), 77–78.
Kurman, R. J., Ellenson, L. H., & Ronnett, B. M. (2019). Nonspesific Tumors of the Ovary, Including Mesenchymal Tumors. In Blaustein's pathology of the female genital tract (pp. 1133–1134). essay, Springer. ISSBN 078-3-319-46334-6
Ziari, K., & Alizadeh, K. (2016). Ovarian Hemangioma: a Rare Case Report and Review of the Literature. Iranian journal of pathology, 11(1), 61–65.
DiOrio, J., Jr, & Lowe, L. C. (1980). Hemangioma of the ovary in pregnancy: a case report. The Journal of reproductive medicine, 24(5), 232–234.
Kaneta, Y., Nishino, R., Asaoka, K., Toyoshima, K., Ito, K., & Kitai, H. (2003). Ovarian
hemangioma presenting as pseudo-Meigs' syndrome with elevated CA125. The journal of obstetrics and gynaecology research, 29(3), 132–135. https://doi.org/10.1046/j.1341-8076.2003.00088.x
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