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EVALUATION OF CARDIAC CONDUCTION SYSTEM IN SUDDEN DEATH CASES

Yıl 2013, Cilt: 27 Sayı: 1, 10 - 15, 30.04.2013
https://izlik.org/JA76AB67XH

Öz

ABSTRACT
Objective:
In this study, revealing the regional characteristics of the cardiac
conduction system pathologies
in sudden death cases is aimed.
Besides, this is the first study of
Adana region forensic cases related to the cardiac conduction
system pathologies.
Methods:
Twenty seven cases of sudden
unexpected death and 4 cases
with known causes of death as a
control group have been included
in the study. Samples from sinoatrial node and atrioventicular
node were taken in total 31 cases.
Samples were evaluated with light
microscope after staining through
histochemical staining methods.
Results:
There were significant pathological
changes of the sinoatrial node
and atrioventricular node in
10 of the cases. And in 3 of all
cases (11.1%), the abnormalities
of the conduction system were
considered to have the possibility
for causing death.
Conclusion:
We have concluded that it is
of importance to evaluate the
cardiac conduction system in
sudden unexpected death cases
and this topic should be kept in
sight in forensic pathology

Kaynakça

  • Gordon I, Shapiro HA. Forensic Medicine, 2nd Ed., Edinburg, London, Melbourne, New York: Longman Group Limited, 1982.
  • Cohle SD, Saurez-Mier MP, Aguilera B. Sudden death resulting from lesions of the cardiac conduction system. Am J Foren Med Path 2002;23:83-9. Denfield SW, Garson A. Sudden death in children and young adults. Pediatric Clinics of North America 1990;37(1):215-31.
  • James TN, Kamb ML, Sandberg GA, Silver RM, Kilbourne EM. Postmortem studies of the heart in three fatal cases of the eosinophilia-myalgia syndrome. Ann Intern Med 1991;115:102-10.
  • Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Volta SD. Ventricular fibrillation without apparent heart disease: Description of six cases. American Heart Journal 1989;118:1203-9. Sheppard M, Davies JM. Practical Cardiovascular Pathology. 2nd Ed., New York: Oxford University Press, 1998.
  • Myerburg RJ, Kessler KM, Castellanos A. Sudden cardiac death: Epidemiology, transient risk, and intervention assessment. Ann Intern Med 1993;119:1187–97.
  • National Institutes of Health. Report of the Working Group on Arteriosclerosis of the National Heart, Lung, and Blood Institute (Volume 2): Patient Oriented Research. Fundamental and Applied, Sudden Cardiac Death. Washington, D.C. U.S. Government Printing Office Publication 1981;82:2035.
  • Basso C, Corrado D, Thiene G. Congenital coronary artery anomalies as an important cause of sudden death in the young. Cardiol Rev 2001;9:312–7.
  • Virmani R, Burke AP, Farb A. Sudden cardiac death. Cardiovasc Pathol 2001;10:211-8.
  • Hutchins GM. Special studies on the heart and lung. In, Collins KA, Hutchins GM. eds. Autopsy performance and reporting. 2nd Ed., Collage of American Pathologists 2003;219-28.
  • Gulino SP. Examination of the cardiac conduction system - forensic application in cases of sudden cardiac death. Am J Foren Med Path 2003;24:227-38.
  • Charlton I, Williams R. Cardiac conduction tissue, a simplified technique for examination of the SA and AV nodes. Am J Foren Med Path 1990;11:213-8.
  • Michaud K, Romain N, Taroni F, Horisberger B, Mangin P. Evaluation of a simplified method of the conduction system analysis in 110 forensic cases. Forensic Sci Int 2002;130:13-24.
  • Nishida N, Ikeda N, Kudo K, Tsuji A, Kiyoshima A. Forensic significance of conduction system abnormalities as a precise cause of accidental death. Int J Legal Med 2002;116:344-9.
  • Song Y, Zbu J, Laaksonen H, Saukko PA. Modified method for examining the cardiac conduction system. Forensic Sci Int 1997;86:135-8.
  • Goldman L. Ventricular Arrhythmias and Sudden Death. In, Goldman L, Bennett JC. eds. Cecil Textbook of Medicine. 21st Ed., Philadelphia, Pennsylvania: W. B. Saunders Company., 2000: 245-8.
  • Gülmen MK, Salaçin S; Tuncer İ. rhytmogenic right ventricular displasia and sudden young adult deaths. The Bulletin of Legal Medicine 1997;2:35-8.
  • James TN. The sinus node. Am J Cardiol 1977;40:965-86.
  • Johnson WD, Strong JP, Oalmann MC, Newman WP, Tracy RE, Rock WA. Sudden death from coronary heart disease in young man. Arch Pathol Lab Med 1981;105:227-32.
  • Lev M. The Conduction System. In, Gould SE. ed. Pathology of the Heart and Blood Vessels. 3rd Ed., Springfield, Illinois: Charles C Thomas-Publisher, 1968:180-209.
  • Malamou-Mitsi V, Pappa L, Vougiouklakis T, Peschos D, Kazakos N, Grekas G, Sideris D, Agnantis NJ. Sudden death due to an unrecognized cardiac hydatid cyst. J Forensic Sci 2002;47:1062-4.
  • Polson CY, Gee DJ. The Essentials of Forensic Medicine. 3rd Ed., Oxford, New York, Toronto, Sydney, Braunschweig. Pergamon Press, 1973:561-9.
  • Scala-Barnett DM, Donoghue ER. Sudden death in mitral valve prolapse. J Forensic Sci 1998;33:84-91.
  • Schwartz CJ, Gerrity RG. Anatomical pathology of sudden unexpected cardiac death. Circulation 1975;52:18-26.
  • Song Y, Yao Q, Zhu J, Bin L, Liang S. Agerelated variation in the intersiticial tissues of the cardiac conduction system, and autopsy study of 230 Han Chinese. Forensic Sci Int 1999;104:133-42. REFERENCES
  • Song Y, Laaksonen H, Saukko P, Tiovonen S, Zhu J. Histopathological findings of cardiac conduction system of 150 Finns. Forensic Sci Int 2001;119:310–7.
  • Burke AP, Farb A, Virmani R. Causes of sudden death in athletes. The Athlete’s Heart 1992;10:303-17.
  • Hilal A. Evaluation of chlamydia pneumonia antigen in various arteries. Forensic Medicine Speciality Thesis. Çukurova University, Adana, Turkey 1998
  • Bakker JMT, Capelle FJL, Janse MJ, Wilde AAM, Coronel R, Becker AE, Dingemans KP, Hemel NM, Hauer RNW. Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: Electrophysiologic and anatomic correlation. Circulation 1988;77:589-606.
  • Byard RW, Smith NM, Bourne AJ. Association of right coronary artery hypoplasia with sudden death in an eleven-year-old child. J Forensic Sci 1991;36:1234-9.
  • Cohle SD, Lie JT. Pathologic changes of the cardiac conduction tissue in sudden unexpected death: A review. Pathology Annual 1991;26:33-57.
  • Ferris JAJ, Parkin JM. Occlusion of the atrioventricular nodal artery in congenital heart block. Beitr Path Bd 1973;149:311-5.
  • Wreford FS, Conradi SE, Cohle SD, Lie JT, Dana SE, Puri S. Sudden death caused by coronary artery aneurysms: A late complication of Kawasaki disease. J Forensic Sci 1991;36:51-9.
  • Brown DL, Wetli CV, Davis JH. Sudden unexpected death from primary pulmonary hypertension. J Forensic Sci 1981;26:381-6.
  • Bromberg BI, Lindsay LD, Cain ME, Cox JL. Impact of clinical history and electrophysiologic characterization of accessory pathways on management strategies to reduce sudden death among children with Wolff-Parkinson-White Syndrome. J Am Coll Cardiol 1996;27:690- 5.
  • Cohle SD, Graham MA, Dowling G, Pounder DJ. Sudden death and left ventricular outflow disease. Pathology Annual 1988;2:97-124.
  • Waller BF, Gering LE, Branyas NA, Slack JD. Clinical, pathologic correlations - anatomy, histology and pathology of the cardiac conduction system – part VI. Clin Cardiol 1993;16:623-8.
  • Green JR, Korovezt MJ, Shanklin DR, DeVito JJ, Taylor WJ. Sudden unexpected death in three generations. Arch Intern Med 1969;124:359-63.
  • Lenegre J. Etiology of bilateral bundle branch fibrosis in relation to complete heart block. Prog Cardiovasc Dis 1964;6:317–20.
  • Ridolfi RL, Bulkley BH, Hutchins GM. The conduction system in cardiac amyloidosis. Am J Med 1977;62:677-86.
  • Corrado D, Thiene G, Nava A, Rossi L, Pennelli N. Sudden death in young competitive athletes: Clinicopathologic correlations in 22 cases. Am J Med, 1990;89:588-96.
  • James TN, MacLean WAH. Paroxysmal ventricular arrhythmias and familial sudden death associated with neural lesions in the heart. Chest 1980;78:24-30.
  • James TN, Martin ES, Willis PW, Lohr TO. Apoptosis as a possible cause of gradual development of complete heart block and fatal arrhythmias associated with absence of the AV node, sinus node, and internodal pathways. Circulation 1996;93:1424-38.
  • Virmani R, Burke AP, Farb A. Sudden cardiac death. Cardiovascular Pathology 2001;10(5):211-8.
  • Smith ET, Davis GJ. Sudden cardiac death associated with hypoplasia of the coronary arteries and conduction system alteration. Am J Foren Med Path 1997;18:189-93.

Yıl 2013, Cilt: 27 Sayı: 1, 10 - 15, 30.04.2013
https://izlik.org/JA76AB67XH

Öz

Kaynakça

  • Gordon I, Shapiro HA. Forensic Medicine, 2nd Ed., Edinburg, London, Melbourne, New York: Longman Group Limited, 1982.
  • Cohle SD, Saurez-Mier MP, Aguilera B. Sudden death resulting from lesions of the cardiac conduction system. Am J Foren Med Path 2002;23:83-9. Denfield SW, Garson A. Sudden death in children and young adults. Pediatric Clinics of North America 1990;37(1):215-31.
  • James TN, Kamb ML, Sandberg GA, Silver RM, Kilbourne EM. Postmortem studies of the heart in three fatal cases of the eosinophilia-myalgia syndrome. Ann Intern Med 1991;115:102-10.
  • Martini B, Nava A, Thiene G, Buja GF, Canciani B, Scognamiglio R, Daliento L, Volta SD. Ventricular fibrillation without apparent heart disease: Description of six cases. American Heart Journal 1989;118:1203-9. Sheppard M, Davies JM. Practical Cardiovascular Pathology. 2nd Ed., New York: Oxford University Press, 1998.
  • Myerburg RJ, Kessler KM, Castellanos A. Sudden cardiac death: Epidemiology, transient risk, and intervention assessment. Ann Intern Med 1993;119:1187–97.
  • National Institutes of Health. Report of the Working Group on Arteriosclerosis of the National Heart, Lung, and Blood Institute (Volume 2): Patient Oriented Research. Fundamental and Applied, Sudden Cardiac Death. Washington, D.C. U.S. Government Printing Office Publication 1981;82:2035.
  • Basso C, Corrado D, Thiene G. Congenital coronary artery anomalies as an important cause of sudden death in the young. Cardiol Rev 2001;9:312–7.
  • Virmani R, Burke AP, Farb A. Sudden cardiac death. Cardiovasc Pathol 2001;10:211-8.
  • Hutchins GM. Special studies on the heart and lung. In, Collins KA, Hutchins GM. eds. Autopsy performance and reporting. 2nd Ed., Collage of American Pathologists 2003;219-28.
  • Gulino SP. Examination of the cardiac conduction system - forensic application in cases of sudden cardiac death. Am J Foren Med Path 2003;24:227-38.
  • Charlton I, Williams R. Cardiac conduction tissue, a simplified technique for examination of the SA and AV nodes. Am J Foren Med Path 1990;11:213-8.
  • Michaud K, Romain N, Taroni F, Horisberger B, Mangin P. Evaluation of a simplified method of the conduction system analysis in 110 forensic cases. Forensic Sci Int 2002;130:13-24.
  • Nishida N, Ikeda N, Kudo K, Tsuji A, Kiyoshima A. Forensic significance of conduction system abnormalities as a precise cause of accidental death. Int J Legal Med 2002;116:344-9.
  • Song Y, Zbu J, Laaksonen H, Saukko PA. Modified method for examining the cardiac conduction system. Forensic Sci Int 1997;86:135-8.
  • Goldman L. Ventricular Arrhythmias and Sudden Death. In, Goldman L, Bennett JC. eds. Cecil Textbook of Medicine. 21st Ed., Philadelphia, Pennsylvania: W. B. Saunders Company., 2000: 245-8.
  • Gülmen MK, Salaçin S; Tuncer İ. rhytmogenic right ventricular displasia and sudden young adult deaths. The Bulletin of Legal Medicine 1997;2:35-8.
  • James TN. The sinus node. Am J Cardiol 1977;40:965-86.
  • Johnson WD, Strong JP, Oalmann MC, Newman WP, Tracy RE, Rock WA. Sudden death from coronary heart disease in young man. Arch Pathol Lab Med 1981;105:227-32.
  • Lev M. The Conduction System. In, Gould SE. ed. Pathology of the Heart and Blood Vessels. 3rd Ed., Springfield, Illinois: Charles C Thomas-Publisher, 1968:180-209.
  • Malamou-Mitsi V, Pappa L, Vougiouklakis T, Peschos D, Kazakos N, Grekas G, Sideris D, Agnantis NJ. Sudden death due to an unrecognized cardiac hydatid cyst. J Forensic Sci 2002;47:1062-4.
  • Polson CY, Gee DJ. The Essentials of Forensic Medicine. 3rd Ed., Oxford, New York, Toronto, Sydney, Braunschweig. Pergamon Press, 1973:561-9.
  • Scala-Barnett DM, Donoghue ER. Sudden death in mitral valve prolapse. J Forensic Sci 1998;33:84-91.
  • Schwartz CJ, Gerrity RG. Anatomical pathology of sudden unexpected cardiac death. Circulation 1975;52:18-26.
  • Song Y, Yao Q, Zhu J, Bin L, Liang S. Agerelated variation in the intersiticial tissues of the cardiac conduction system, and autopsy study of 230 Han Chinese. Forensic Sci Int 1999;104:133-42. REFERENCES
  • Song Y, Laaksonen H, Saukko P, Tiovonen S, Zhu J. Histopathological findings of cardiac conduction system of 150 Finns. Forensic Sci Int 2001;119:310–7.
  • Burke AP, Farb A, Virmani R. Causes of sudden death in athletes. The Athlete’s Heart 1992;10:303-17.
  • Hilal A. Evaluation of chlamydia pneumonia antigen in various arteries. Forensic Medicine Speciality Thesis. Çukurova University, Adana, Turkey 1998
  • Bakker JMT, Capelle FJL, Janse MJ, Wilde AAM, Coronel R, Becker AE, Dingemans KP, Hemel NM, Hauer RNW. Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: Electrophysiologic and anatomic correlation. Circulation 1988;77:589-606.
  • Byard RW, Smith NM, Bourne AJ. Association of right coronary artery hypoplasia with sudden death in an eleven-year-old child. J Forensic Sci 1991;36:1234-9.
  • Cohle SD, Lie JT. Pathologic changes of the cardiac conduction tissue in sudden unexpected death: A review. Pathology Annual 1991;26:33-57.
  • Ferris JAJ, Parkin JM. Occlusion of the atrioventricular nodal artery in congenital heart block. Beitr Path Bd 1973;149:311-5.
  • Wreford FS, Conradi SE, Cohle SD, Lie JT, Dana SE, Puri S. Sudden death caused by coronary artery aneurysms: A late complication of Kawasaki disease. J Forensic Sci 1991;36:51-9.
  • Brown DL, Wetli CV, Davis JH. Sudden unexpected death from primary pulmonary hypertension. J Forensic Sci 1981;26:381-6.
  • Bromberg BI, Lindsay LD, Cain ME, Cox JL. Impact of clinical history and electrophysiologic characterization of accessory pathways on management strategies to reduce sudden death among children with Wolff-Parkinson-White Syndrome. J Am Coll Cardiol 1996;27:690- 5.
  • Cohle SD, Graham MA, Dowling G, Pounder DJ. Sudden death and left ventricular outflow disease. Pathology Annual 1988;2:97-124.
  • Waller BF, Gering LE, Branyas NA, Slack JD. Clinical, pathologic correlations - anatomy, histology and pathology of the cardiac conduction system – part VI. Clin Cardiol 1993;16:623-8.
  • Green JR, Korovezt MJ, Shanklin DR, DeVito JJ, Taylor WJ. Sudden unexpected death in three generations. Arch Intern Med 1969;124:359-63.
  • Lenegre J. Etiology of bilateral bundle branch fibrosis in relation to complete heart block. Prog Cardiovasc Dis 1964;6:317–20.
  • Ridolfi RL, Bulkley BH, Hutchins GM. The conduction system in cardiac amyloidosis. Am J Med 1977;62:677-86.
  • Corrado D, Thiene G, Nava A, Rossi L, Pennelli N. Sudden death in young competitive athletes: Clinicopathologic correlations in 22 cases. Am J Med, 1990;89:588-96.
  • James TN, MacLean WAH. Paroxysmal ventricular arrhythmias and familial sudden death associated with neural lesions in the heart. Chest 1980;78:24-30.
  • James TN, Martin ES, Willis PW, Lohr TO. Apoptosis as a possible cause of gradual development of complete heart block and fatal arrhythmias associated with absence of the AV node, sinus node, and internodal pathways. Circulation 1996;93:1424-38.
  • Virmani R, Burke AP, Farb A. Sudden cardiac death. Cardiovascular Pathology 2001;10(5):211-8.
  • Smith ET, Davis GJ. Sudden cardiac death associated with hypoplasia of the coronary arteries and conduction system alteration. Am J Foren Med Path 1997;18:189-93.
Toplam 44 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Adli Biyoloji
Bölüm Araştırma Makalesi
Yazarlar

Ramazan Karanfil Bu kişi benim

Ahmet Hilal Bu kişi benim

Necmi Çekin Bu kişi benim

Gönderilme Tarihi 18 Haziran 2012
Yayımlanma Tarihi 30 Nisan 2013
IZ https://izlik.org/JA76AB67XH
Yayımlandığı Sayı Yıl 2013 Cilt: 27 Sayı: 1

Kaynak Göster

Vancouver 1.Ramazan Karanfil, Ahmet Hilal, Necmi Çekin. EVALUATION OF CARDIAC CONDUCTION SYSTEM IN SUDDEN DEATH CASES. ATD [Internet]. 01 Nisan 2013;27(1):10-5. Erişim adresi: https://izlik.org/JA76AB67XH

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